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Immunogenicity of Therapeutic Proteins
The use of proteins for medical applications has revolutionized therapies of many diseases/disorders that were often incurable with small-molecule... -
Presynaptic Cytomatrix Proteins
The Cytomatrix Assembled at the active Zone (CAZ) of a presynaptic terminal displays electron-dense appearance and defines the center of the synaptic... -
Utilization and prospect of purification technologies in natural proteins, peptides and recombinant proteins
Protein, being a fundamental biological macromolecule, assumes a critical function in various vital activities of cellular growth, heredity,...
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BioID Analysis of Actin-Binding Proteins
Proteins often exist and function as part of higher-order complexes or networks. A challenge is to identify the universe of proximal and interacting... -
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Proximity Ligation Assay to Detect the Proximity Between Host Proteins and Viral Proteins of HIV-1
The study of host-pathogen interaction often requires interrogating the protein-protein interactions and examining post-translational modifications... -
Therapeutic Fusion Proteins
Therapeutic fusion proteins are a class of hybrid constructs that combine distinct biomolecules into a single platform with the additive effects of...
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Biophysical and Biochemical Characteristics of Therapeutic Proteins
Pharmaceutical proteins are large, folded structures stabilized by weak physical/chemical forces. An appreciation of the factors that may influence... -
Fucosylated Proteins as Cancer Biomarkers
Fucosylation, a type of glycosylation associated with cancer and inflammation, involves the attachment of fucose residues to glycans. Fucosylation is... -
Cell Wall-Anchored Surface Proteins of Staphylococcus aureus
Staphylococcus aureus expresses a plethora of proteins that are covalently anchored to cell wall peptidoglycan. They are classified on the basis of... -
Proteins Associated with Neurodevelopmental Disorders
This book comprehensively reviews the proteins associated with neurodevelopmental disorders, including autism spectrum disorder (ASD) and attention...
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Production and Purification of Recombinant Proteins
The growing demand for therapeutic proteins, especially monoclonal antibodies, increases the need for practical and economical processing techniques.... -
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The Role of RNA-Binding Proteins in Cancers
RNA-binding proteins (RBPs) play fundamental roles in most aspects of cell regulation, specifically in post-transcriptional modifications, thanks to... -
S100 proteins: a new frontier in fibromyalgia research
Fibromyalgia (FM) is a chronic condition that causes widespread pain, fatigue, and other symptoms that significantly affect quality of life. The...
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Absolute quantification of DNA damage response proteins
BackgroundDNA damage response (DDR) and repair are vital for safeguarding genetic information and ensuring the survival and accurate transmission of...
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Therapeutic Applications of Snake Venom Proteins as Anti-cancer Agents
Cancer is a life debilitating fatal disease that affects millions of lives annually across the world. The current cancer treatments include invasive...