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1. RNA m6A methylation regulators in liver cancer

   Liver cancer is one of the most common cancers in the world and a primary cause of cancer-related death. In recent years, despite the great...

   Qiao** Xu, Ning Ren, ... Hongkai Shang in Cancer Cell International

   Article Open access 02 January 2024
   

2. Morphine-Driven m6A Epitranscriptomic Neuroadaptations in Primary Cortical Cultures

   Opioid overdose is the leading cause of accidental death in the United States and remains a major public health concern, despite significant...

   Konrad R. Dabrowski, Stephanie E. Daws in Molecular Neurobiology

   Article Open access 23 May 2024
   

3. Role of m6A RNA Methylation in Ischemic Stroke

   Ischemic stroke is a prominent contributor to global morbidity and mortality rates. The intricate and diverse mechanisms underlying...

   Yayun Xu, Wenqiang Liu, Lijie Ren in Molecular Neurobiology

   Article 16 February 2024
   

4. Recent advances of m6A methylation in skeletal system disease

   Skeletal system disease (SSD) is defined as a class of chronic disorders of skeletal system with poor prognosis and causes heavy economic burden....

   Jianhui Liang, Qian Yi, ... Weichao Sun in Journal of Translational Medicine

   Article Open access 14 February 2024
   

5. METTL14/YTHDC1-Mediated m6A Modification in Hippocampus Improves Pentylenetetrazol-Induced Acute Seizures

   Epilepsy is a common neurological disorder which can cause significant morbidity and mortality. N6-methyladenosine (m6A), the most common chemical...

   **aolin Zhong, Ling Chen, ... Xuyu Zu in Molecular Neurobiology

   Article 30 May 2024
   

6. Comprehensive analysis of m6A modification in immune infiltration, metabolism and drug resistance in hepatocellular carcinoma

   N6-methyladenosine (m6A) is important in regulating mRNA stability, splicing, and translation, and it also contributes to tumor development. However,...

   Yunxing Shi, Kai Li, ... Wei He in Cancer Cell International

   Article Open access 16 April 2024
   

7. Comprehensive analysis of m6A modification in lipopolysaccharide-induced acute lung injury in mice

   Background

   N6-Methyladenosine (m6A) methylation is the most prevalent post-transcriptional modification in mRNA, and plays significant roles in...

   Chenzhen Xu, Congkuan Song, ... Qing Geng in Molecular Medicine

   Article Open access 22 January 2024
   

8. Implication of m6A Methylation Regulators in the Immune Microenvironment of Bronchopulmonary Dysplasia

   N ⁶ -methyladenosine (m6A) regulates gene expression and governs many important biological processes. However, the function of m6A in the development...

   Tian** Bao, Haiyan Zhu, ... Zhaofang Tian in Biochemical Genetics

   Article 23 February 2024
   

9. Direct Analysis of HIV mRNA m6A Methylation by Nanopore Sequencing

   The post-transcriptional processing and chemical modification of HIV RNA are understudied aspects of HIV virology, primarily due to the limited...

   Ethan Honeycutt, Fredrick Kizito, ... Thomas Sweet in HIV Protocols

   Protocol 2024
   

10. m6A reader IGF2BP2 promotes lymphatic metastasis by stabilizing DPP4 in papillary thyroid carcinoma

    Lymph node metastasis (LNM) is a major cause of locoregional recurrence of papillary thyroid carcinoma (PTC). However, the mechanisms responsible for...

    Wenlong Wang, Ying Ding, ... **nying Li in Cancer Gene Therapy

    Article 15 December 2023
    

11. m6A-YTHDF1 Mediated Regulation of GRIN2D in Bladder Cancer Progression and Aerobic Glycolysis

    The modification of N6-methyladenosine (m6A), primarily orchestrated by the reader protein YTHDF1, is a pivotal element in the post-transcriptional...

    Meixian Le, Meiying Qing, ... Shunhua Cheng in Biochemical Genetics

    Article 29 June 2024
    

12. Profiling the role of m6A effectors in the regulation of pluripotent reprogramming

    The N ⁶ -methyladenosine (m ⁶ A) RNA modification plays essential roles in multiple biological processes, including stem cell fate determination. To...

    Wenjun Wang, Lei Zhou, ... Jiuwei Cui in Human Genomics

    Article Open access 02 April 2024
    

13. Construction of a Prognostic Risk Prediction Model Based on m6A-Associated Long Non-Coding RNAs in Cholangiocarcinoma

    Abstract

    To screen long non-coding RNAs (lncRNAs) associated with the N6-methyladenosine (m6A) gene and create a prognostic risk model for...

    Y. Dai, S. Zhang, ... Q. He in Russian Journal of Genetics

    Article 21 May 2024
    

14. Altered m6A RNA methylation governs denervation-induced muscle atrophy by regulating ubiquitin proteasome pathway

    Background

    Denervation-induced muscle atrophy is complex disease involving multiple biological processes with unknown mechanisms. N6-methyladenosine...

    Junjie Sun, Hai Zhou, ... Hualin Sun in Journal of Translational Medicine

    Article Open access 23 November 2023
    

15. The role of m6A methylation in therapy resistance in cancer

    Cancer therapy resistance is the main cause of cancer treatment failure. The mechanism of therapy resistance is a hot topic in epigenetics. As one of...

    Hengzhao Zhuang, Bo Yu, ... Lili Wang in Molecular Cancer

    Article Open access 01 June 2023
    

16. m6A-regulated tumor glycolysis: new advances in epigenetics and metabolism

    Glycolytic reprogramming is one of the most important features of cancer and plays an integral role in the progression of cancer. In cancer cells,...

    Shi-Wei Yue, Hai-Ling Liu, ... Wei Zhang in Molecular Cancer

    Article Open access 15 August 2023
    

17. Transcriptome-wide map of N6-methyladenosine (m6A) profiling in coronary artery disease (CAD) with clopidogrel resistance

    Background

    Clopidogrel resistance profoundly increases the risk of major cardiovascular events in coronary artery disease (CAD) patients. Here, we...

    Ruoyan Yu, Qinglin Yu, ... Jia Su in Clinical Epigenetics

    Article Open access 15 December 2023
    

18. The m6A reader IGF2BP2 promotes esophageal cell carcinoma progression by enhancing EIF4A1 translation

    Esophageal squamous cell carcinoma (ESCC) is one of most prevalent cancers worldwide, especially in China. Lacking in depth mechanism study,...

    Yuan Li, Zhuya **ao, ... Zuhua Chen in Cancer Cell International

    Article Open access 09 May 2024
    

19. The Landscape of m6A Regulators in Multiple Brain Regions of Alzheimer’s Disease

    Alzheimer’s disease research has been conducted for many years, yet no effective cure methods have been found. N6-methyladenosine (m6A) RNA...

    ZiJie Liu, Qing **a, ... Xu Gao in Molecular Neurobiology

    Article 05 June 2023
    

20. ALKBH5 facilitates CYP1B1 mRNA degradation via m6A demethylation to alleviate MSC senescence and osteoarthritis progression

    Improving health and delaying aging is the focus of medical research. Previous studies have shown that mesenchymal stem cell (MSC) senescence is...

    Guiwen Ye, **teng Li, ... Huiyong Shen in Experimental & Molecular Medicine

    Article Open access 01 August 2023