Search
Search Results
-
Surrogacy of one-year survival for overall survival in advanced hepatocellular carcinoma
BackgroundThe increasing number of sequential treatments complicates the evaluation of overall survival (OS) in clinical trials for hepatocellular...
-
Progression-free survival as a surrogate endpoint for overall survival in patients with relapsed or refractory multiple myeloma
ObjectivesThe goal of the research was to assess the quantitative relationship between median progression-free survival (PFS) and median overall...
-
Overall survival of patients with thyroid cancer in Martinique (2008–2018)
BackgroundThyroid cancer (TC) overall survival at 5 years was estimated at 97% in mainland France over 2010–2015. Its prognosis is known to be...
-
Real-world overall survival with abiraterone acetate versus enzalutamide in chemotherapy-naïve patients with metastatic castration-resistant prostate cancer
BackgroundThere are no large head-to-head phase 3 clinical trials comparing overall survival (OS) for abiraterone and enzalutamide. This study used...
-
Development and validation of a nomogram for predicting overall survival in patients with sinonasal mucosal melanoma
BackgroundSinonasal mucosal melanoma (SNMM) is a relatively rare malignant tumour with a poor prognosis. This study was designed to identify...
-
Correlation between overall survival and quality of life in colon cancer patients with chemotherapy
BackgroundPatients presenting with inoperable colon cancer at first onset (ICF) or at time of relapse (ICR) are considered in unrecoverable. The...
-
Effect of adjuvant radiotherapy on overall survival and breast cancer-specific survival of patients with malignant phyllodes tumor of the breast in different age groups: a retrospective observational study based on SEER
PurposeMalignant phyllodes tumor of the breast (MPTB) is a rare type of breast cancer, with an incidence of less than 1%. The value of adjuvant...
-
Overall survival of patients with hepatocellular carcinoma treated with sintilimab and disease outcome after treatment discontinuation
BackgroundThe use of Anti-PD-1 therapy has yielded promising outcomes in hepatocellular carcinoma (HCC). However, limited research has been conducted...
-
Tumor Growth Inhibition-Overall Survival (TGI-OS) Model for Subgroup Analysis Based on Post-Randomization Factors: Application for Anti-drug Antibody (ADA) Subgroup Analysis of Atezolizumab in the IMpower150 Study
Longitudinal changes of tumor size or tumor-associated biomarkers have been receiving growing attention as early markers of treatment benefits. Tumor...
-
Surgery versus no surgery in platinum-sensitive relapsed ovarian cancer: final overall survival analysis of the SOC-1 randomized phase 3 trial
Surgery for platinum-sensitive, relapsed ovarian cancer (PSROC) is widely practiced but had contradictory survival outcomes in previous studies. In...
-
Identification on surrogating overall survival with progression-free survival of first-line immunochemotherapy in advanced esophageal squamous cell carcinoma—an exploration of surrogate endpoint
BackgroundOverall survival (OS) is the gold standard to assess novel therapeutics to treat cancer. However, to identify early efficacy and speed up...
-
Functional genetic variants of GEN1 predict overall survival of Chinese epithelial ovarian cancer patients
BackgroundInherited variations in DNA double-strand break (DSB) repair pathway are known to influence ovarian cancer occurrence, progression and...
-
Machine learning models predict overall survival and progression free survival of non-surgical esophageal cancer patients with chemoradiotherapy based on CT image radiomics signatures
PurposeTo construct machine learning models for predicting progression free survival (PFS) and overall survival (OS) with esophageal squamous cell...
-
Machine learning prediction of pathological complete response and overall survival of breast cancer patients in an underserved inner-city population
BackgroundGeneralizability of predictive models for pathological complete response (pCR) and overall survival (OS) in breast cancer patients requires...
-
Factors associated with overall survival in breast cancer patients with leptomeningeal disease (LMD): a single institutional retrospective review
BackgroundBreast cancer-related leptomeningeal disease (BC-LMD) is a dire diagnosis for 5–8% of patients with breast cancer (BC). We conducted a...
-
Factors associated with overall survival, progression-free survival and toxicity in patients with small cell lung cancer and thoracic irradiation in a clinical real-world setting
BackgroundSmall-cell lung cancer (SCLC) is a malignant tumor known for its poor prognosis. In addition to chemotherapy and immunotherapy irradiation...
-
A multi-parametric prognostic model based on clinicopathologic features: vessels encapsulating tumor clusters and hepatic plates predict overall survival in hepatocellular carcinoma patients
BackgroundVessels encapsulating tumor clusters (VETC) is a newly described vascular pattern that is distinct from microvascular invasion (MVI) in...
-
Prognostic model on overall survival in elderly nasopharyngeal carcinoma patients: a recursive partitioning analysis identifying pre-treatment risk stratification
BackgroundWe aimed to evaluate the optimal management for elderly patients with nasopharyngeal carcinoma (NPC) with intensity-modulated radiotherapy...
-
Updated overall survival from the MONALEESA-3 trial in postmenopausal women with HR+/HER2− advanced breast cancer receiving first-line ribociclib plus fulvestrant
BackgroundThe phase III MONALEESA-3 trial included first- (1L) and second-line (2L) patients and demonstrated a significant overall survival (OS)...
-
Development of a well-defined tool to predict the overall survival in lung cancer patients: an African based cohort
BackgroundNomogram is a graphic representation containing the expressed factor of the mathematical formula used to define a particular phenomenon. We...
