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Immune-related lncRNAs signature and radiomics signature predict the prognosis and immune microenvironment of glioblastoma multiforme
BackgroundGlioblastoma multiforme (GBM) is the most common primary malignant brain tumor in adults. This study aimed to construct immune-related long...
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Anoikis-related signature predicts prognosis and characterizes immune landscape of ovarian cancer
Ovarian cancer (OV) is the most lethal gynecological malignancy worldwide, with high recurrence rates. Anoikis, a newly-acknowledged form of...
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Stemness related lncRNAs signature for the prognosis and tumor immune microenvironment of ccRCC patients
Long non-coding RNAs (lncRNAs) and cancer stem cells (CSCs) are crucial for the growth, migration, recurrence, and medication resistance of tumors....
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Suppressive stroma-immune prognostic signature impedes immunotherapy in ovarian cancer and can be reversed by PDGFRB inhibitors
BackgroundAs the most lethal gynecologic cancer, ovarian cancer (OV) holds the potential of being immunotherapy-responsive. However, only modest...
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Comment on “A novel super-enhancer-related gene signature predicts prognosis and immune microenvironment for breast cancer”
The primary aim of this study is to critically evaluate and comment on the research presented in the article titled “A Novel...
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A novel signature to predict thyroid cancer prognosis and immune landscape using immune-related LncRNA pairs
BackgroundThyroid cancer (TC) is the most common endocrine malignancy worldwide. The incidence of TC is high and increasing worldwide due to...
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A novel prognostic signature based on smoking-associated genes for predicting prognosis and immune microenvironment in NSCLC smokers
BackgroundAs a highly heterogeneous tumor, non-small cell lung cancer (NSCLC) is famous for its high incidence and mortality worldwide. Smoking can...
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A necroptosis-related gene signature to predict prognosis and immune features in hepatocellular carcinoma
Background and AimNecroptosis plays an important role in hepatocellular carcinoma (HCC) development, recurrence, and immunotherapy tolerance. We...
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Immune regulation and prognosis indicating ability of a newly constructed multi-genes containing signature in clear cell renal cell carcinoma
BackgroundClear cell renal cell carcinoma (ccRCC) is the most common renal malignancy, although newly develo** targeted therapy and immunotherapy...
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A novel super-enhancer-related gene signature predicts prognosis and immune microenvironment for breast cancer
BackgroundThis study targeted at develo** a robust, prognostic signature based on super-enhancer-related genes (SERGs) to reveal survival prognosis...
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The cuproptosis-related signature predicts the prognosis and immune microenvironments of primary diffuse gliomas: a comprehensive analysis
BackgroundEvidence has revealed a connection between cuproptosis and the inhibition of tumor angiogenesis. While the efficacy of a model based on...
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A ubiquitin–proteasome system-related signature to predict prognosis, immune infiltration, and therapy efficacy for breast cancer
The ubiquitin–proteasome system (UPS) is an essential regulatory system for maintaining homeostasis, and its dysfunction may cause various diseases....
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Identification of a basement membrane-related genes signature with immune correlation in bladder urothelial carcinoma and verification in vitro
BackgroundBladder urothelial carcinoma (BLCA) is the most common genitourinary cancer and the prognosis of patients is often poor. However, studies...
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Development and validation of ferroptosis-related lncRNA signature and immune-related gene signature for predicting the prognosis of cutaneous melanoma patients
Ferroptosis, a form of cell death caused by iron-dependent peroxidation of lipids, plays an important role in cancer. Recent studies have shown that...
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Clinical significance and immune infiltration analyses of a novel coagulation-related signature in ovarian cancer
Ovarian cancer (OV) is the most lethal gynecological malignancies worldwide. The coagulation cascade could induce tumor cell infiltration and...
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Immune characteristics analysis and construction of a four-gene prognostic signature for lung adenocarcinoma based on estrogen reactivity
Lung adenocarcinoma (LUAD) is a common type of malignant tumor with poor prognosis and high mortality. In our previous studies, we found that...
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The heterogeneity of tumour immune microenvironment revealing the CRABP2/CD69 signature discriminates distinct clinical outcomes in breast cancer
BackgroundIt has been acknowledged that the tumour immune microenvironment (TIME) plays a critical role in determining therapeutic responses and...
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Identification of a novel lymphangiogenesis signature associated with immune cell infiltration in colorectal cancer based on bioinformatics analysis
BackgroundLymphangiogenesis plays an important role in tumor progression and is significantly associated with tumor immune infiltration. However, the...
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A signature based on five immune-related genes to predict the survival and immune characteristics of neuroblastoma
BackgroundMYCN amplification (MNA) has been proved to be related to poor prognosis in neuroblastoma (NBL), but the MYCN-related immune signatures and...
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Construction of immune-related signature and identification of S100A14 determining immune-suppressive microenvironment in pancreatic cancer
Pancreatic cancer (PC) is a highly lethal and aggressive disease with its incidence and mortality quite discouraging. A robust prognostic signature...
