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1. Colorectal Cancer

   Carcinomas of the colon and rectum (colorectal cancer, CRC) are among the most prevalent cancers worldwide. Colorectal cancers develop through a...

   Wolfgang A. Schulz in Molecular Biology of Human Cancers

   Chapter 2023
   

2. Multi-Omics Data Analysis for Cancer Research: Colorectal Cancer, Liver Cancer and Lung Cancer

   Cancer is a multifactorial disease caused by the malfunction and modification of numerous biological entities, including genes, proteins, mRNAs,...

   Hantao Zhang, Xun Gong, Min Tang in Methodologies of Multi-Omics Data Integration and Data Mining

   Chapter 2023
   

3. Challenges of Onco-therapeutics in Early-Onset Colorectal Cancer

   The incidence of colorectal cancer among adults aged less than 50 is rising. Patients with early-onset colorectal cancer are more likely to present...

   Katie Doogan, Alexandra M. Zaborowski, Des C. Winter in Gastrointestinal Cancers: An Interdisciplinary Approach

   Chapter 2023
   

4. Azoxymethane/Dextran Sodium Sulfate (AOM/DSS) Model of Colorectal Cancer

   Recent progress in develo** new vaccination strategies against cancer requires the production of complex and reliable animal models reflecting the...

   Mariangela De Robertis, Emanuela Signori in Mouse Models of Cancer

   Protocol 2024
   

5. Role of Circulating Tumor DNA in Colorectal Cancer

   Colorectal cancer (CRC) is a very common gastrointestinal tumor, ranking second in the global cause of cancer death. Because of the invasive nature...

   Haotian Li, Sheng Lu, ... Yong Shao in Liquid Biopsies

   Protocol 2023
   

6. Preclinical Models in Colorectal Cancer Drug Discovery

   Currently, colorectal cancer (CRC) remains one of the most common causes of cancer-related death worldwide despite advances in medical therapies of...

   Ying Yang, Wen-Jian Meng, Zi-Qiang Wang in Handbook of Animal Models and its Uses in Cancer Research

   Reference work entry 2023
   

7. Renin-Angiotensin System: A Potential Therapeutic Target for Colorectal Cancer

   The Renin-Angiotensin System (RAS) is associated with regulation of blood pressure, electrolyte balance, and hemostasis. It is implicated in cancer...

   Lokesh Kumar Bhatt, Niraj Parihar, Kedar S. Prabhavalkar in The Renin Angiotensin System in Cancer, Lung, Liver and Infectious Diseases

   Chapter 2023
   

8. Polysaccharide-Based Nano-delivery Systems for the Treatment of Colorectal Cancer

   Use of nano-delivery systems for the treatment of colorectal cancer has been tried successfully for almost all known varieties of such delivery...

   Leander Corrie, Monica Gulati, ... Harish Dureja in Handbook of Oncobiology: From Basic to Clinical Sciences

   Reference work entry 2024
   

9. Development of Biocompatible Nanocarriers for the Treatment of Colorectal Cancer

   Colorectal cancer is one of the top three cancers with highest incidence in the world. Therapies using medication remain one of the common treatment...

   Bibi Noorheen Haleema Mooneerah Neeroa, Nurshafida Adzlin Shamsul Anuar, ... Sin-Yeang Teow in Gastrointestinal Cancers: An Interdisciplinary Approach

   Chapter 2023
   

10. Colorectal Cancer and Role of Biomarkers in Diagnosis, Prognostification and Personalized Treatment

    Colorectal cancer (CRC) is the second leading cause of cancer-related mortality worldwide as per GLOBOCAN 2020. One out of five patients is diagnosed...

    Divya Khosla, Aditya Kumar Singla, ... Rakesh Kapoor in Molecular Biomarkers for Cancer Diagnosis and Therapy

    Chapter 2024
    

11. Heavy-metal associated breast cancer and colorectal cancer hot spots and their demographic and socioeconomic characteristics

    Purpose

    Cancer registries offer an avenue to identify cancer clusters across large populations and efficiently examine potential environmental harms...

    Madeline M. Tomlinson, Felicia Pugh, ... Natalie C. DuPré in Cancer Causes & Control

    Article Open access 25 June 2024
    

12. Germline NPAT inactivating variants as cause of hereditary colorectal cancer

    Two independent exome sequencing initiatives aimed to identify new genes involved in the predisposition to nonpolyposis colorectal cancer led to the...

    Mariona Terradas, Stephanie A. Schubert, ... Tom van Wezel in European Journal of Human Genetics

    Article 22 May 2024
    

13. Role of Chemokines in Colorectal Cancer

    Colorectal cancer (CRC) is one of the most common causes for cancer-related deaths worldwide. Chemokines, structurally related cytokines, are present...

    Manisha Mathur, Sonal Gupta, ... Obul Reddy Bandapalli in Colon Cancer Diagnosis and Therapy Vol. 3

    Chapter 2022
    

14. Sexual dimorphism in colorectal cancer: molecular mechanisms and treatment strategies

    Introduction

    Sexual dimorphism significantly influences cancer incidence and prognosis. Notably, females exhibit a lower risk and favorable prognosis...

    Yair Rodríguez-Santiago, Claudia Angelica Garay-Canales, ... Jorge Morales-Montor in Biology of Sex Differences

    Article Open access 12 June 2024
    

15. STK16 promoted colorectal cancer progress in a c-MYC signaling-dependent manner

    Background

    Colorectal cancer standed as a global health challenge, ranking third in cancer incidence and second in cancer-related deaths worldwide. A...

    Li Peng, Liu Guangshi, ... Li Tao in Molecular Medicine

    Article Open access 15 April 2024
    

16. Polysaccharide-Based Nano-Delivery Systems for the Treatment of Colorectal Cancer

    Use of nano-delivery systems for the treatment of colorectal cancer has been tried successfully for almost all known varieties of such delivery...

    Leander Corrie, Monica Gulati, ... Harish Dureja in Handbook of Oncobiology: From Basic to Clinical Sciences

    Living reference work entry 2023
    

17. Recent Advancements in the Inhibition of Metastasis of Colorectal Cancer Using Anticancer Compounds

    Colorectal cancer (CRC) is the second most common cancer with a high mortality rate. CRC is a multistep process that begins with genetic and...

    Dibyashree Chhetri, Ilango Kaliappan, ... Dhanavathy Gnanasampanthapandian in Handbook of Oncobiology: From Basic to Clinical Sciences

    Reference work entry 2024
    

18. Atovaquone inhibits colorectal cancer metastasis by regulating PDGFRβ/NF-κB signaling pathway

    Background

    Colorectal cancer is a common malignant tumour. Invasive growth and distant metastasis are the main characteristics of its malignant...

    Bin Liu, ** Zhao in BMC Cancer

    Article Open access 06 November 2023
    

19. A Comprehensive Review on the Effect of Natural Products on Colorectal Cancer

    Purpose of Review

    This article provides insight and information on selected natural products against colorectal cancer and its mechanism of action.

    ...

    V. A. Afrose Farzana, Sekar Kumaran, Ashok Kumar Pandurangan in Current Pharmacology Reports

    Article 13 December 2023
    

20. Probing the diabetes and colorectal cancer relationship using gene – environment interaction analyses

    Background

    Diabetes is an established risk factor for colorectal cancer. However, the mechanisms underlying this relationship still require...

    Niki Dimou, Andre E. Kim, ... Ulrike Peters in British Journal of Cancer

    Article Open access 26 June 2023