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Clinical features, treatment, and outcomes of cavernous sinus dural arteriovenous fistulas: a cohort study of 141 patients
PurposeThe cavernous sinus (CS) region is a common region of dural arteriovenous fistula (DAVF). Over time, treatment strategies are gradually...
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Carotid Cavernous Fistulas
Carotid cavernous fistulas (CCFs) are pathologic connections between the cavernous segment of the carotid artery and the cavernous venous sinus. It... -
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Intracranial extra-axial chondromas: clues to computed tomography and magnetic resonance imaging diagnosis
AimWe aimed to describe the computed tomography (CT) and magnetic resonance (MR) imaging findings of intracranial extra-axial chondroma.
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Characteristics of patients with cerebral sinus venous thrombosis and JAK2 V617F mutation
ObjectivesJanus kinase 2 (JAK2–V617F) mutations can cause thrombocytosis, polycythemia and hyper viscosity leading to cerebral sinus venous...
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Efficacy and safety of direct oral anticoagulants versus warfarin in the treatment of cerebral venous sinus thrombosis
BackgroundGiven the evolving application and promising outcomes of direct oral anticoagulants (DOACs) in various thromboembolic conditions, we aimed...
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Endothelial hyperactivation of mutant MAP3K3 induces cerebral cavernous malformation enhanced by PIK3CA GOF mutation
Cerebral cavernous malformations (CCMs) refer to a common vascular abnormality that affects up to 0.5% of the population. A somatic gain-of-function...
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Unraveling the patterns and pathways of local recurrence of nasopharyngeal carcinoma: evidence for individualized clinical target volume delineation
BackgroundsDespite publication of international guidelines, there are notable controversial points of clinical target volume (CTV) delineation in...
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CCNB1 affects cavernous sinus invasion in pituitary adenomas through the epithelial–mesenchymal transition
BackgroundTo investigate the relationship between cyclin B1 (CCNB1) gene expression and cavernous sinus invasion in pituitary adenomas.
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Pediatric cerebral sinus venous thrombosis: clinical characterization of a Portuguese cohort
IntroductionPediatric cerebral sinus venous thrombosis (CSVT) is a rare entity. Risk factors differ from the adults, and treatment is not consensual....
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A novel BRAF::PTPRN2 fusion in meningioma: a case report
Gene fusion events have been linked to oncogenesis in many cancers. However, gene fusions in meningioma are understudied compared to somatic...
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Rhombomere 5 r5
The structures of the auditory pathways (see Sect. 9.1.6 Nuclei of the superior olivary complex) have been dealt together with the cochlear nuclei... -
A Novel Mouse Model for Cerebral Venous Sinus Thrombosis
Cerebral venous sinus thrombosis (CVST) is an uncommon cause of stroke resulting in parenchymal injuries associated with heterogeneous clinical...
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Monogenic Causes in Familial Stroke Across Intracerebral Hemorrhage and Ischemic Stroke Subtypes Identified by Whole-Exome Sequencing
Whole exome sequencing (WES) has been used to detect rare causative variants in neurological diseases. However, the efficacy of WES in genetic...
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Research Advances in Stem Cell Therapy for Erectile Dysfunction
Erectile dysfunction (ED) is a common clinical condition that mainly affects men aged over 40 years. Various causes contribute to the progression of...
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Surgical Management of Brain Cavernous Malformations
Surgical removal of accessible lesions is the only direct therapeutic approach for cerebral cavernous malformations (CCMs). The approach should be... -
The dural angioleiomyoma harbors frequent GJA4 mutation and a distinct DNA methylation profile
The International Society for the Study of Vascular Anomalies (ISSVA) has defined four vascular lesions in the central nervous system (CNS):...
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Intracranial dural arteriovenous fistula: a comprehensive review of the history, management, and future prospective
Dural arteriovenous fistulas (DAVF) are abnormal acquired intracranial vascular malformations consisting of pathological connections located within...
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Brain Tumors Affecting the Orbit Globe and Orbit Tumors Affecting the Brain
Brain tumorsBrain tumor affecting the orbitOrbit and orbital tumorsOrbital tumors affecting the brain are a heterogeneousHeterogeneous group of...