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CaPTure: Calcium PeakToolbox for analysis of in vitro calcium imaging data
BackgroundCalcium imaging is a powerful technique for recording cellular activity across large populations of neurons. However, analysis methods...
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In Vivo Calcium Imaging of Peripheral Ganglia
Calcium dynamics are a proxy for neuronal firing, yet studying those dynamics requires dissociation protocols that lead to cellular milieu that may...
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Calcium imaging of adult olfactory epithelium reveals amines as important odor class in fish
The odor space of aquatic organisms is by necessity quite different from that of air-breathing animals. The recognized odor classes in teleost fish...
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Characterization of Endo-Lysosomal Cation Channels Using Calcium Imaging
Endo-lysosomes are membrane-bound acidic organelles that are involved in endocytosis, recycling, and degradation of extracellular and intracellular...
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A one-photon endoscope for simultaneous patterned optogenetic stimulation and calcium imaging in freely behaving mice
Optogenetics and calcium imaging can be combined to simultaneously stimulate and record neural activity in vivo. However, this usually requires...
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A deep learning framework for inference of single-trial neural population dynamics from calcium imaging with subframe temporal resolution
In many areas of the brain, neural populations act as a coordinated network whose state is tied to behavior on a millisecond timescale. Two-photon...
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A Calcium Imaging Approach to Measure Functional Sensitivity of Neurons
Pain associated with chemotherapy and radiation therapy is one of the most common reasons for discontinuation of these treatments and has a dramatic...
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Pharmacogenomic Screening of Drug Candidates using Patient-Specific hiPSC-Derived Cardiomyocyte High-Throughput Calcium Imaging
Calcium imaging is an invaluable technique to detect and characterize calcium flux in cells. The use of calcium dye provides information on the...
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Imaging Somatosensory Cortex in Rodents
The rodent somatosensory cortex has been investigated using a range of electrophysiological techniques, from intracellular recordings to...
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CADENCE — Neuroinformatics Tool for Supervised Calcium Events Detection
CADENCE is an open Python 3-written neuroinformatics tool with Qt6 graphic user interface for supervised calcium events detection. In neuronal...
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Fiber photometry in striatum reflects primarily nonsomatic changes in calcium
Fiber photometry enables recording of population neuronal calcium dynamics in awake mice. While the popularity of fiber photometry has grown in...
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Iron-Calcium Crosstalk in Neurodegenerative Diseases
Iron and calcium have one thing in common: they are both required for appropriate neural activity. Neuronal calcium impulses drive neurochemical...
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A database and deep learning toolbox for noise-optimized, generalized spike inference from calcium imaging
Inference of action potentials (‘spikes’) from neuronal calcium signals is complicated by the scarcity of simultaneous measurements of action...
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Calcium channel inhibitor and extracellular calcium improve aminoglycoside-induced hair cell loss in zebrafish
Aminoglycosides are commonly used antibiotics for treatment of gram-negative bacterial infections, however, they might act on inner ear, leading to...
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A Simple Ca2+-Imaging Approach of Network-Activity Analyses for Human Neurons
Rapid advances in light microscopy and development of all-optical electrophysiological imaging tools have greatly leveraged the speed and the depth...
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Cisplatin Provokes Peripheral Nociception and Neuronal Features of Therapy-Induced Senescence and Calcium Dysregulation in Rats
Therapy-Induced Senescence (TIS) is a form of senescence that is typically described in malignant cells in response to the exposure of cancer...
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Elevated Calcium after Acute Ischemic Stroke Predicts Severity and Prognosis
The aim of this study is to investigate whether there is a correlation between serum calcium levels and clinical severity or functional outcome at...
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Ca2+ Imaging in Immature Cortical Neurons
Ca2+ signaling plays a central role in various neurodevelopmental steps, and immature neurons exhibit spontaneous Ca2+ activity. To analyze Ca2+...
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RCN2 promotes Nasopharyngeal carcinoma progression by curbing Calcium flow and Mitochondrial apoptosis
ObjectiveEvidence suggests that calcium release from the endoplasmic reticulum (ER) can be induced to cause calcium overload, which in turn can...
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TNFα Enhances Calcium Influx by Interacting with AMPA Receptors in the Spinal Dorsal Horn Neurons
Tumor necrosis factor alpha (TNFα) is a proinflammatory cytokine and has been implicated in pain regulation. Neuronal activity in the spinal dorsal...
