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Localization of natriuretic peptide receptors A, B, and C in healthy and diseased mouse kidneys
The natriuretic peptides (NPs) ANP (atrial natriuretic peptide) and BNP (B-type natriuretic peptide) mediate their widespread effects by activating...
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Synthesis and Excretion of Atrial Natriuretic Peptide in Secretory Cardiomyocytes in Experimental Hypertension
The intensity of accumulation and excretion of atrial natriuretic peptide in myocytes of the right atrium in rat models of renovascular hypertension...
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Chamber-specific regulation of atrial natriuretic peptide secretion in cardiac hypertrophy: atrial wall dynamics in the ANP secretion
The heart is involved in the regulation of blood pressure and body fluid homeostasis. As a blood volume sensor and effector for the regulation of the...
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Treatment of murine colitis by Saccharomyces boulardii secreting atrial natriuretic peptide
AbstractInflammatory bowel disease is a lifelong disorder that involves chronic inflammation in the small and large intestines. Current therapies,...
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Gene duplication of C-type natriuretic peptide-4 (CNP4) in teleost lineage elicits subfunctionalization of ancestral CNP
The diversified natriuretic peptide (NP) family, consisting of four CNPs (CNP1-4), ANP, BNP, and VNP, has been identified in the eel. Here, we...
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Platelet Analysis in the Thrombus Plus Serum BNP for Detecting Clot-Related Atrial Fibrillation. Results From the ITACAT Multicentric Registry
Occult atrial fibrillation (AF) is a common cause of cryptogenic stroke. This study aimed to investigate the utility of surrogate markers within the...
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Paracrine and endocrine pathways of natriuretic peptides assessed by ligand-receptor map** in the Japanese eel brain
The natriuretic peptide (NP) family consists of cardiac NPs (ANP, BNP, and VNP) and brain NPs (CNPs) in teleosts. In addition to CNP1-4, a paralogue...
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Role of natriuretic peptides in the cardiovascular-adipose communication: a tale of two organs
Natriuretic peptides have long been known for their cardiovascular function. However, a growing body of evidence emphasizes the role of natriuretic...
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Peptide Acylation in Aliphatic Polyesters: a Review of Mechanisms and Inhibition Strategies
Biodegradable polyesters are widely employed in the development of controlled release systems for peptide drugs. However, one of the challenges in...
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Therapeutic advances in atrial fibrillation based on animal models
Atrial fibrillation (AF) is the most prevalent sustained cardiac arrhythmia among humans, with its incidence increasing significantly with age....
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Causal effects between atrial fibrillation and heart failure: evidence from a bidirectional Mendelian randomization study
BackgroundObservational studies have suggested a close association between atrial fibrillation (AF) and heart failure (HF), yet the causal effect...
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Identification of Plasmatic MicroRNA-206 as New Predictor of Early Recurrence of Atrial Fibrillation After Catheter Ablation Using Next-generation Sequencing
BackgroundCatheter ablation (CA) of atrial fibrillation (AF) is indicated in patients with recurrent and symptomatic AF episodes. Despite the strict...
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Comparison of Protective Effect of Tri-circulator and Coenzyme Q10 on Myocardial Injury and the Mechanism Study by Zebrafish Model
Tri-Circulator (TC) is a product comprising coenzyme Q10 (CoQ10), Salvia miltiorrhiza , and Panax notoginseng . Individually, each of these...
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Bleeding risk factors and real-world antithrombotic therapies in elderly patients with atrial fibrillation undergoing percutaneous coronary intervention: a retrospective study
BackgroundBleeding risk factors in elderly patients with atrial fibrillation undergoing percutaneous coronary intervention (PCI) are unclear and data...
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Cyanidin prevents cardiomyocyte apoptosis in mice after myocardial infarction
Myocardial infarction is a worldwide disease with high morbidity and mortality and a major cause of chronic heart failure, seriously affecting...
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Predicting Atrial Fibrillation with High Risk of Embolization with Atrial Strain and NT-proBNP
The aim of the study was to determine markers of atrial dysfunction in patients with cryptogenic stroke to predict episodes of paroxysmal atrial...