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Antifungal Drug Resistance Methods and Protocols
This detailed volume aims to elucidate the molecular mechanisms that underlie antifungal resistance. The book highlights methods to identify and...
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Synthesis, structure-activity relationship and evaluation of antifungal activity of tryptanthrin derivatives against drug-resistant Candida albicans
With the increasing of Candida albicans infections year by year, and the widespread use of azole drugs, especially fluconazole has led to the...
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New Antifungal Drugs: Discovery and Therapeutic Potential
There has been an increase in invasive fungal infections, which are a universal problem due to the longer average lifespan, the number of...
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New Systemic Antifungal: Isavuconazole
Invasive fungal infections have been increasing with the increased use of immunosuppressive drugs for the treatment of cancer, organ, stem cell and...
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Biosynthesis, Structural, Spectroscopic, Photoluminescence, and Antifungal Activity of Ni-doped CeO2 Nanoparticles
Pedalium Murex leaf extract was used in this study to create Nickel-doped Cerium oxide (Ni-CeO 2 ) nanoparticles at 3 mol% and 5 mol% molar...
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Screening of Phyllanthus niruri Plant Active Constituents for Anticancer and Antifungal Activity by Insilico Methods
A large genus of shrubs, trees, and rare plants belonging to the Euphorbiaceae family, Phyllanthus contains 600–700 species. The Phyllanthus niruri...
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DOCK2 regulates antifungal immunity by regulating RAC GTPase activity
Fungal infections cause ~1.5 million deaths each year worldwide, and the mortality rate of disseminated candidiasis currently exceeds that of breast...
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Pulmonary surfactant impacts in vitro activity of selected antifungal drugs against Candida krusei and Candida albicans
PurposeThis study investigates how surfactants affect the in-vitro anti-infective efficacy of micafungin, caspofungin, anidulafungin, and...
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Para-Hydroxy Benzoic Acid Coformer Enable Enhanced Solubility, Dissolution, and Antifungal Activity of Ketoconazole Cocrystals
PurposeThe present investigation was aimed at preparing ketoconazole cocrystals using phenolic acid coformers.
MethodThe slow solvent evaporation...
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Emerging Antifungal Resistance in Fungal Pathogens
Purpose of ReviewOver recent decades, the number of outbreaks caused by fungi has increased for humans, plants (including important crop species) and...
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Analysis of Candida Antifungal Resistance Using Animal Infection Models
Candida frequently produces three general disease states, including mucosal candidiasis, disseminated candidiasis, and biofilm infection (which can...
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Luciferase-Based High-Throughput Screen with Aspergillus fumigatus to Identify Antifungal Small Molecules
Only three classes of contemporary antifungal drugs are routinely utilized in the clinic against filamentous fungal pathogens such as Aspergillus...
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Antifungal Susceptibility of Yeasts and Filamentous Fungi by CLSI Broth Microdilution Testing
Antifungal susceptibility testing is performed against yeasts and filamentous fungi (molds) for various purposes. In clinical settings, the results...
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Phytochemical analysis and antibacterial/antifungal activity of the essential oil of Phlomis olivieri Benth in Iran
Phlomis olivieri Benth. is an aromatic plant endemic to Iran belonging to the Lamiaceae family. It is used to treat pain, stomach ache and common...
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Antibacterial, antifungal activities and toxicity of new synthetic fatty acid salicylate esters
Microbial threats and their resistance to the available drugs are public health concerns that scientists worldwide are trying to solve. Before the...
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β-Tubulin of Fusarium as a Potential Target for Realization of Antifungal Activity of Ivermectin
The analysis of the effect of ivermectin on phytopathogenic strains of Fusarium graminearum (F‑55644, F-55748) and Fusarium oxysporum f. sp. lycopersici...
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Antifungal Susceptibility Testing and Drug Discovery in the Dimorphic Fungus Histoplasma Capsulatum
The thermal dimorphism of the fungal pathogen Histoplasma is linked to its virulence in mammalian hosts. Mammalian body temperature triggers...
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Synthesis, antifungal activity, and molecular dynamics study of novel geranyl aromatic sulfonamide compounds as potential complex III inhibitors
Essential oils ( EO s), as unique natural products, are promising resources for the discovery of green agrochemicals. The main ingredient geraniol of...
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In-vitro evaluation of Indigofera heterantha extracts for antibacterial, antifungal and anthelmintic activities
BackgroundMultidrug-resistant bacterial strains cause several serious infections that can be fatal, such as Enterococcus faecium , Staphylococcus...
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Pseudolaric acid B exerts an antifungal effect and targets SIRT1 to ameliorate inflammation by regulating Nrf2/NF-κB pathways in fungal keratitis
Fungal keratitis (FK) is a vision-threatening infection. We aimed to explore the antifungal and anti-inflammatory effects of pseudolaric acid B (PAB)...
