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Malignant Glioma
This chapter provides a comprehensive overview of malignant gliomasMalignant glioma, the most common primary brain tumorPrimary brain tumor in...
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Benign Glioma
BenignBenign gliomaGliomas broadly refers to a heterogeneousHeterogeneous group of slow-growing glial tumors with low proliferative rates and a more...
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NMDA Glutamate Receptor Expression Activity in Anaplastic Astrocytomas
Objectives . To study the relationship between the expression activity of NMDA glutamate receptors and the proliferative activity and genetic...
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Temozolomide and flavonoids against glioma: from absorption and metabolism to exosomal delivery
Patients with glioblastoma multiforme and anaplastic astrocytoma are treated with temozolomide. Although it has been demonstrated that temozolomide...
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Ibuprofen inhibits anaplastic thyroid cells in vivo and in vitro by triggering NLRP3-ASC-GSDMD-dependent pyroptosis
Pyroptosis is a novel type of proinflammatory programmed cell death that is associated with inflammation, immunity, and cancer. Anaplastic thyroid...
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From bench to bedside: the application of cannabidiol in glioma
Glioma is the most common malignant tumor in central nervous system, with significant health burdens to patients. Due to the intrinsic...
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Forkhead box transcription factors (FOXOs and FOXM1) in glioma: from molecular mechanisms to therapeutics
Glioma is the most aggressive and malignant type of primary brain tumor, comprises the majority of central nervous system deaths, and is categorized...
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Tracking tumor alteration in glioma through serum fibroblast activation protein combined with image
PurposeDetecting tumor progression of glioma continues to pose a formidable challenge. The role of fibroblast activation protein (FAP) in gliomas has...
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Reactive Oxygen Species in Glioma
Glioma represents the lethal neoplasm of the brain with dismal progression in its most aggressive form, that is, glioblastoma. Hypoxia is well...
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Reactive Oxygen Species in Glioma
Glioma represents the lethal neoplasm of the brain with dismal progression in its most aggressive form, that is, glioblastoma. Hypoxia is well...
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IDH1 mutation is detectable in plasma cell-free DNA and is associated with survival outcome in glioma patients
BackgroundCirculating cell-free DNA (cfDNA, liquid biopsy) is a powerful tool to detect molecular alterations. However, depending on tumor...
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Seizure control by adding on other anti-seizure medication on seizure during levetiracetam administration in patients with glioma-related epilepsy
BackgroundEpilepsy is a major symptom in patients with glioma. Levetiracetam (LEV) is recognized as a first-line treatment for glioma-related...
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Ibrutinib disrupts blood-tumor barrier integrity and prolongs survival in rodent glioma model
In malignant glioma, cytotoxic drugs are often inhibited from accessing the tumor site due to the blood-tumor barrier (BTB). Ibrutinib, FDA-approved...
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Serum lipids concentration on prognosis of high-grade glioma
ObjectiveTo investigate the effect of serum lipids concentration on the prognosis of high-grade glioma patients undergoing postoperative radiotherapy.
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Glycosylation spectral signatures for glioma grade discrimination using Raman spectroscopy
BackgroundGliomas are the most common brain tumours with the high-grade glioblastoma representing the most aggressive and lethal form. Currently,...
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Integrated bioinformatics analysis and experimental validation reveal ISG20 as a novel prognostic indicator expressed on M2 macrophage in glioma
BackgroundGlioma is the most common malignant primary brain tumor and is characterized by a poor prognosis and limited therapeutic options. ISG20...
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Role of TP53 Gene in Glioma
Wild-type (wt) p53 protein conditional expression in the glioblastoma tumor cell line inhibited its growth at the restriction point in the cell cycle...
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Graded Differentiation of Glioma in GSK-3 β: The Study and Analysis of the Expression Difference and Its Significance in the Endoplasmic Reticulum Stress Apoptosis Pathway
AbstractGlioma accounts for 80% of malignant central nervous system, with high incidence and extremely difficult to cure. However, for the role of ER...
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LncRNA SNHG25 Promotes Glioma Progression Through Activating MAPK Signaling
Numerous studies indicated that long non-coding RNAs (lncRNAs) play critical roles in glioma initiation and progression. SNHG25 is a newly identified...
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Auto-Segmentation and Classification of Glioma Tumors with the Goals of Treatment Response Assessment Using Deep Learning Based on Magnetic Resonance Imaging
Glioma is the most common primary intracranial neoplasm in adults. Radiotherapy is a treatment approach in glioma patients, and Magnetic Resonance...
