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Metabolism Pharmacology
Safety pharmacology defines studies that investigate the potential undesirable pharmacodynamic effects of a substance on physiological functions in...
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Drug Metabolism
Living systems have developed elimination mechanisms to dispose of waste products and protect themselves from exposure to potentially harmful...
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Cardiac Metabolism
The heart is composed of a heterogeneous mixture of cellular components perfectly intermingled and able to integrate common environmental signals to...
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Evaluation of Metabolism-Dependent Drug Toxicity
Drug metabolism is well-established to play key roles in drug toxicity. Drug toxicity can be enhanced via biotransformation of a parent drug to...
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Metabolism of Cancer Stem Cell
Nowadays, cancer is considered as a stem cell disease of altered metabolism. The metabolism of cancer stem cells (CSCs) is less well characterized...
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Exercise Metabolism
In this Edited Volume, a diverse group of exercise metabolism experts, assembled a multi-facetted collection of fascinating contributions. The...
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Perspectives on Retinal Dolichol Metabolism, and Visual Deficits in Dolichol Metabolism-Associated Inherited Disorders
De novo synthesis of dolichol (Dol) and dolichyl phosphate (Dol-P) is essential for protein glycosylation. Herein, we provide a brief overview of Dol...
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Dysregulations of amino acid metabolism and lipid metabolism in urine of children and adolescents with major depressive disorder: a case-control study
RationaleThe mechanisms underlying major depressive disorder (MDD) in children and adolescents are unclear. Metabolomics has been utilized to capture...
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RNA Metabolism Governs Immune Function and Response
Inflammation is a complex process that protects our body from various insults such as infection, injury, and stress. Proper inflammation is...
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Metabolism in Hematopoiesis and Its Malignancy
Hematopoietic stem cells (HSCs) are multipotent stem cells that can self-renew and generate all blood cells of different lineages. The system is...
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Serine metabolism in macrophage polarization
ObjectiveEmerging studies have revealed that macrophages possess different dependences on the uptake, synthesis, and metabolism of serine for their...
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A two-way street – cellular metabolism and myofibroblast contraction
Tissue fibrosis is characterised by the high-energy consumption associated with myofibroblast contraction. Although myofibroblast contraction relies...
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Lipid metabolism: the potential targets for toxoplasmosis treatment
Toxoplasmosis is a zoonosis caused by Toxoplasma gondii ( T. gondii ). The current treatment for toxoplasmosis remains constrained due to the absence...
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Tumor Metabolism: Challenges and Future Perspectives
Cancer can be characterized as a set of more than 200 diseases that have in common the capacity for disordered growth and increased invasive...
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Immune regulation through tryptophan metabolism
Amino acids are fundamental units of molecular components that are essential for sustaining life; however, their metabolism is closely interconnected...
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Cancer cell metabolism and antitumour immunity
Accumulating evidence suggests that metabolic rewiring in malignant cells supports tumour progression not only by providing cancer cells with...
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Phosphate Metabolism From Physiology to Toxicity
This contributed volume discusses the most important physiological aspects of phosphate metabolism, and how its pathological dysregulation can induce...
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Identification and validation of iron metabolism genes in osteoporosis
BackgroundOsteoporosis is the most common metabolic bone disease in humans. Exploring the expression difference of iron metabolism-related genes in...
