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Immunostimulant, hepatoprotective, and nephroprotective potential of Bacillus subtilis (NMCC-path-14) in comparison to dexamethasone in alleviating CFA-induced arthritis
To investigate and compare efficacy as well as safety of Bacillus subtilis and dexamethasone (Dexa) in complete Freund’s adjuvant (CFA)-induced...
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Subdivisions of Neural Tube along the Rostrocaudal Axis: Neuromeric Models
This chapter discusses the transverse subdivisions, which are positioned perpendicular to the longitudinal axis of the neural tube. The medaka neural...
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Enhanced antichemobrain activity of amino acid assisted ferulic acid solid dispersion in adult zebrafish (Danio rerio)
Chemotherapy-induced cognitive impairment (CICI), also known as “chemobrain,” is a common side effect of breast cancer therapy which causes oxidative...
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Presepsin as a prognostic biomarker in COVID-19 patients: combining clinical scoring systems and laboratory inflammatory markers for outcome prediction
BackgroundThere is still limited research on the prognostic value of Presepsin as a biomarker for predicting the outcome of COVID-19 patients....
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Assessment of lipolysis biomarkers in adipose tissue of patients with gastrointestinal cancer
BackgroundAdipose tissue metabolism may be impaired in patients with cancer. In particular, increased lipolysis was described in cancer-promoting...
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Association between metabolic syndrome and early-stage colorectal cancer
BackgroundAccumulating studies have suggested metabolic syndrome (MetS) contributed to colorectal cancer (CRC) development. However, advanced CRC...
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Unifying gamma passing rates in patient-specific QA for VMAT lung cancer treatment based on data assimilation
This study aimed to identify systematic errors in measurement-, calculation-, and prediction-based patient-specific quality assurance (PSQA) methods...
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Synaptic vesicle glycoprotein 2 A in serum is an ideal biomarker for early diagnosis of Alzheimer’s disease
BackgroundPrevious studies have demonstrated that early intervention was the best plan to inhibit the progression of Alzheimer’s disease (AD), which...
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Effect of serum lactate dehydrogenase-to-albumin ratio (LAR) on the short-term outcomes and long-term prognosis of colorectal cancer after radical surgery
BackgroundWhether serum lactate dehydrogenase-to-albumin ratio (LAR) influenced the outcomes of colorectal cancer (CRC) patients after radical...
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Advanced gastrointestinal stromal tumor: reliable classification of imatinib plasma trough concentration via machine learning
AimPatients with advanced gastrointestinal stromal tumors (GISTs) exhibiting an imatinib plasma trough concentration (IM C min ) under 1100 ng/ml may...
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Monoamine Oxidase B (MAO-B): A Target for Rational Drug Development in Schizophrenia Using PET Imaging as an Example
Monoamine oxidase B (MAO-B) is an important high-density enzyme involved in the generation of oxidative stress and central in the catabolism of...
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Recommended Resources for Biomarkers in Diabetes: Methods, Discoveries, and Applications
Diabetes mellitus is a treatable disease characterized by persistent hyperglycemia. Its prevalence is spiraling out of control, resulting in...
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Single-Cell Sequencing Reveals the Expression of Immune-Related Genes in Macrophages of Diabetic Kidney Disease
Diabetic kidney disease (DKD) is characterized by macrophage infiltration, which requires further investigation. This study aims to identify...
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Macrolides for Cancer
Macrolides exert their antitumor effects through various mechanisms. Clarithromycin markedly reduced the incidence of mucosa-associated lymphoid...
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Engineered exosomes as an in situ DC-primed vaccine to boost antitumor immunity in breast cancer
BackgroundDendritic cells (DCs) are central for the initiation and regulation of innate and adaptive immunity in the tumor microenvironment. As such,...
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Renaming of genera Ebolavirus and Marburgvirus to Orthoebolavirus and Orthomarburgvirus, respectively, and introduction of binomial species names within family Filoviridae
The International Committee on Taxonomy of Viruses (ICTV) Filoviridae Study Group continues to prospectively refine the established nomenclature for...
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Prevalence, clinical significance, and persistence of autoantibodies in COVID-19
BackgroundInterest in complications and sequelae following Coronavirus disease 2019 (COVID-19) is increasing. Several articles have reported...
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Semaphorin 3 a restores the ability of type 1 regulatory T cells to suppress food allergy
Food allergy (FA) is a common immune disorder that involves dysfunctional immune regulation. More remedies for restoring immune regulation are...
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Troponin as a Biomarker: Use in Non-cardiac Surgery
The growing demand for surgical procedures associated with an aging population raises concerns about the risk of perioperative complications. In...
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Clinical significance of genetic profiling based on different anatomic sites in patients with mucosal melanoma who received or did not receive immune checkpoint inhibitors
BackgroundTo date, data on the efficacy of targeted therapies for mucosal melanoma (MM) are limited. In this study, we analyzed genetic alterations...
