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Cardiac Disease Modeling with Engineered Heart Tissue
The rhythmically beating heart is the foundation of life-sustaining blood flow. There are four chambers and many different types of cell in the... -
3D Bioprinting of Skin Tissue Model
The challenges and potential of using tissue engineering and regenerative medicine to create functional skin tissue constructs. While traditional... -
Development of a tissue-engineered skin model with epidermal, dermal and hypodermal components
Tissue-engineered models of skin have evolved over the past 50 years, have successfully been translated to clinical use and continue to be improved...
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3D Bioprinting Strategies for Articular Cartilage Tissue Engineering
Articular cartilage is the avascular and aneural tissue which is the primary connective tissue covering the surface of articulating bone. Traumatic...
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Platelet lysate can support the development of a 3D-engineered skin for clinical application
Safety concerns associated with foetal bovine serum (FBS) have restricted its translation into clinics. We hypothesised that platelet lysate (PL) can...
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A tissue-engineered model of the blood-tumor barrier during metastatic breast cancer
Metastatic brain cancer has poor prognosis due to challenges in both detection and treatment. One contributor to poor prognosis is the blood–brain...
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Fused Deposition Modeling 3D-Printed Scaffolds for Bone Tissue Engineering Applications: A Review
The emergence of bone tissue engineering as a trend in regenerative medicine is forcing scientists to create highly functional materials and scaffold...
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Modulating cardiac physiology in engineered heart tissue with the bidirectional optogenetic tool BiPOLES
Optogenetic actuators are rapidly advancing tools used to control physiology in excitable cells, such as neurons and cardiomyocytes. In neuroscience,...
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Promoting Angiogenesis Using Immune Cells for Tissue-Engineered Vascular Grafts
Implantable tissue-engineered vascular grafts (TEVGs) usually trigger the host reaction which is inextricably linked with the immune system,...
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Modeling angiogenesis in the human brain in a tissue-engineered post-capillary venule
Angiogenesis plays an essential role in embryonic development, organ remodeling, wound healing, and is also associated with many human diseases. The...
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Osteocyte Spheroids as a Live-Cell Additive Proposed as a Component in the Compounding of Biofabricated Materials for Engineered Bone Tissue: Formation and Biological Performance
PurposeTo proposes osteocyte spheroids as a live-cell additive for biofabricated materials in engineered bone tissue.
MethodsThe osteocytes were...
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3D bioprinting using a new photo-crosslinking method for muscle tissue restoration
Three-dimensional (3D) bioprinting is a highly effective technique for fabricating cell-loaded constructs in tissue engineering. However, the...
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Hydrogels for Musculoskeletal Tissue Engineering
The advancements in scaffold-supported cell therapy for musculoskeletal tissue engineering have been truly dramatic in the last couple of decades.... -
Esophageal regeneration following surgical implantation of a tissue engineered esophageal implant in a pediatric model
Diseases of the esophagus, damage of the esophagus due to injury or congenital defects during fetal esophageal development, i.e., esophageal atresia...
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Decellularized Tissue-Induced Cellular Recruitment for Tissue Engineering and Regenerative Medicine
Biomaterials that recapitulate the native in vivo microenvironment are promising to facilitate tissue repair and regeneration when used in...
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Advancements in engineered mesenchymal stem cell exosomes for chronic lung disease treatment
Chronic lung diseases include an array of conditions that impact airways and lung structures, leading to considerable societal burdens. Mesenchymal...
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Engineered Polymeric Materials/Nanomaterials for Growth Factor/Drug Delivery in Bone Tissue Engineering Applications
Accelerating number of bone fractures/disorders, increased global burden, high demand, and limited availability of traditional bone grafts have... -
Breathing new life into tissue engineering: exploring cutting-edge vascularization strategies for skin substitutes
Tissue-engineered skin substitutes (TESS) emerged as a new therapeutic option to improve skin transplantation. However, establishing an adequate and...
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Semisolid Extrusion Printing and 3D Bioprinting
This chapter provides an insightful overview of two transformative technologies in the realm of additive manufacturing: semisolid extrusion printing... -
Design of a Mechanobioreactor to Apply Anisotropic, Biaxial Strain to Large Thin Biomaterials for Tissue Engineered Heart Valve Applications
Repair and replacement solutions for congenitally diseased heart valves capable of post-surgery growth and adaptation have remained elusive. Tissue...