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Open AccessVNP20009-Abvec-Igκ-MIIP suppresses ovarian cancer progression by modulating Ras/MEK/ERK signaling pathway
Ovarian cancer poses a significant threat to women’s health, with conventional treatment methods encountering numerous limitations, and the emerging engineered bacterial anti-tumor strategies offer newfound ho...
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Article
Open AccessAuthor Correction: A shared neural basis underlying psychiatric comorbidity
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Article
Open AccessA shared neural basis underlying psychiatric comorbidity
Recent studies proposed a general psychopathology factor underlying common comorbidities among psychiatric disorders. However, its neurobiological mechanisms and generalizability remain elusive. In this study,...
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Article
Open AccessApplication of machine learning algorithm in predicting distant metastasis of T1 gastric cancer
Distant metastasis (DM) is relatively uncommon in T1 stage gastric cancer (GC). The aim of this study was to develop and validate a predictive model for DM in stage T1 GC using machine learning (ML) algorithms...
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Article
Correction: Tanshinol Inhibits Periodontitis Through IκBα Promotion
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Article
Tanshinol Inhibits Periodontitis Through IκBα Promotion
The main pharmacological strategy for the treatment of periodontitis is inhibition of the inflammatory process. The aim of this study was to investigate whether tanshinol could suppress inflammatory factors an...
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Article
Federated Analysis in COINSTAC Reveals Functional Network Connectivity and Spectral Links to Smoking and Alcohol Consumption in Nearly 2,000 Adolescent Brains
With the growth of decentralized/federated analysis approaches in neuroimaging, the opportunities to study brain disorders using data from multiple sites has grown multi-fold. One such initiative is the Neurom...
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Article
Multi-hierarchical spatial clustering for characteristic towns in China: An Orange-based framework to integrate GIS and Geodetector
As China’s economy and society continue to expand, urbanization in China has reached a new stage. In this context, China’s characteristic town development plans, from the national to the local level, provide a...
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Article
Function of the GABAergic System in Diabetic Encephalopathy
Diabetes is a common metabolic disease characterized by loss of blood sugar control and a high rate of complications. γ-Aminobutyric acid (GABA) functions as the primary inhibitory neurotransmitter in the adul...
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Article
Spatial Patterns, Dependencies, and Disparities of Characteristic Towns and Taobao Towns in China
Small town development plays a crucial role in urban-rural systems, especially in develo** countries. Recently, characteristic towns (CTs) and Taobao towns (TTs), which are two kinds of newly-develo** indu...
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Article
Neuritin Promotes Bone Marrow-Derived Mesenchymal Stem Cell Migration to Treat Diabetic Peripheral Neuropathy
The purpose of this study is to explore the effect and mechanism of neuritin overexpression in the bone marrow on peripheral neuropathy in type 2 diabetic (db/db) mice. We analyzed the impact of bone marrow ne...
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Article
Characterization of chikusetsusaponin IV and V induced apoptosis in HepG2 cancer cells
Chikusetsusaponin IV and V (CsIV and CsV), two typical oleanolic acid saponins, are mainly derived from the rhizome of Panax japonicus C.A. Mey. To reveal the anti-cancer effect of CsIV and CsV on liver cancer ce...
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Article
Structural characterization and biological activities of a new polysaccharide isolated from Morchella Sextelata
Morchella is the famous medicinal fungi in the ascomycetes. In this study, a new water-soluble polysaccharide (MSP-3-1) with an average molecular weight of 2.35 × 107 Da was extracted and purified from fruiting b...
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Article
The impacts of urban land expansion on ecosystem services in Wuhan, China
A clear understanding of the impacts of urban land expansion on ecosystem services is crucial for sustainable urban planning. Although various studies have shown that urban land expansion caused a degradation ...
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Article
Decentralized Multisite VBM Analysis During Adolescence Shows Structural Changes Linked to Age, Body Mass Index, and Smoking: a COINSTAC Analysis
There has been an upward trend in develo** frameworks that enable neuroimaging researchers to address challenging questions by leveraging data across multiple sites all over the world. One such open-source f...
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Chapter and Conference Paper
A GIS-Based K-Mean Clustering Algorithm for Characteristic Towns in China
The unbalanced development among regions and city-towns has attracted considerable attention due to the rapid China’s urbanization process. What promote the characteristic town, a key node in China's urban sys...
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Book and Conference Proceedings
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Article
Differential Modulators of NG2-Glia Differentiation into Neurons and Glia and Their Crosstalk
As the fifth main cell population in the brain, NG2-glia are also known as oligodendrocyte precursor cells. NG2-glia express receptors and ion channels for fast modulation of neuronal activities and signaling ...
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Chapter and Conference Paper
Enlightenment of the Kennedy Space Center of the United States to Development of Space Tourism in Hainan, China
The international influence of Hainan International Tourism Island is not high, which need to create special tourism products to increase their international influence and competitiveness. Aerospace tourism is...
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Article
Regional differences and rural public expenditure cyclicality: evidence from transitory and persistent shocks in China
This paper focuses on the cyclicality of rural public expenditure in China. We employed two types of instrumental variables to estimate the effects of fluctuations in GDP on rural public expenditure based on C...
