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  1. No Access

    Chapter

    Lower Breakpoint of Intracranial Amplitude-Pressure Relationship in Normal Pressure Hydrocephalus

    The relationship between intracranial pulse amplitude (AMP) and mean intracranial pressure (ICP) has been previously described. Generally, AMP increases proportionally to rises in ICP. However, at low ICP a lo...

    Zofia H. Czosnyka, Afroditi D. Lalou in Intracranial Pressure and Neuromonitoring … (2021)

  2. No Access

    Chapter

    External Hydrocephalus After Traumatic Brain Injury: Retrospective Study of 102 Patients

    Introduction: External hydrocephalus (EH) refers to impairment of extra-axial cerebrospinal fluid flow with enlargement of the subarachnoid space (SAS) and concomitant raised intracranial pressure (ICP). It is o...

    Laurent Gergelé, Romain Manet, A. Kolias in Intracranial Pressure and Neuromonitoring … (2021)

  3. No Access

    Chapter

    Global Cerebral Autoregulation, Resistance to Cerebrospinal Fluid Outflow and Cerebrovascular Burden in Normal Pressure Hydrocephalus

    Introduction: We previously examined the relationship between global autoregulation pressure reactivity index (PRx), mean arterial blood pressure (ABP), Resistance to cerebral spinal fluid (CSF) outflow (Rout) a...

    Afroditi D. Lalou, Shadnaz Asgari in Intracranial Pressure and Neuromonitoring … (2021)

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    Chapter

    The Role of Cerebrospinal Fluid Dynamics in Normal Pressure Hydrocephalus Diagnosis and Shunt Prognostication

    Background: Over the years, there have been several reports and trials of the resistance to cerebrospinal fluid (CSF) outflow (Rout) in normal pressure hydrocephalus (NPH). This work aimed to revisit the utility...

    Afroditi D. Lalou, Shadnaz Asgari in Intracranial Pressure and Neuromonitoring … (2021)

  5. No Access

    Chapter

    Analysis of Intracranial Pressure Pulse–Pressure Relationship: Experimental Validation

    The slope of linear relationship between the amplitude of pulsations in intracranial pressure (ICP) versus mean ICP has recently been suggested as a useful guide for selecting patients for shunt surgery in nor...

    Katarzyna Kaczmarska, Piotr Śmielewski in Intracranial Pressure and Neuromonitoring … (2021)

  6. No Access

    Chapter

    Single Center Experience in Cerebrospinal Fluid Dynamics Testing

    Normal pressure hydrocephalus is more complex than a simple disturbance of the cerebrospinal fluid (CSF) circulation. Nevertheless, an assessment of CSF dynamics is key to making decisions about shunt insertio...

    Zofia H. Czosnyka, Marek Czosnyka in Intracranial Pressure and Neuromonitoring … (2021)

  7. No Access

    Chapter

    Differences in Cerebrospinal Fluid Dynamics in Posttraumatic Hydrocephalus Versus Atrophy, Including Effect of Decompression and Cranioplasty

    Introduction: Challenges in diagnosing post-traumatic hydrocephalus (PTH) have created a need for an accurate diagnostic tool. We aim to report CSF dynamics in PTH and atrophy, along with differences before and ...

    Virginia Levrini, Afroditi D. Lalou in Intracranial Pressure and Neuromonitoring … (2021)

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    Chapter

    Comparison of Assessment for Shunting with Infusion Studies Versus Extended Lumbar Drainage in Suspected Normal Pressure Hydrocephalus

    Introduction: Tools available for diagnosis of normal pressure hydrocephalus (NPH) and prediction of shunt-response are overnight ICP monitoring, infusion studies, and extended lumbar drainage (ELD). We investig...

    Virginia Levrini, Matthew Garnett in Intracranial Pressure and Neuromonitoring … (2021)

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    Article

    Correlation between the total number of features of paediatric pseudotumour cerebri syndrome and cerebrospinal fluid pressure

    Accurate diagnosis of pseudotumour cerebri syndrome (PTCS) in children is challenging. We aimed to see if the clinical and radiological assessment that is carried out before lumbar puncture could predict subse...

    James S. McTaggart, Afroditi-Despina Lalou, Nicholas J. Higgins in Child's Nervous System (2020)

  10. Article

    Open Access

    Coupling of CSF and sagittal sinus pressure in adult patients with pseudotumour cerebri

    Pseudotumour cerebri syndrome (PTCS including idiopathic intracranial hypertension) is characterised by the symptoms and signs of raised cerebrospinal fluid pressure (CSFp) in the absence of ventricular dilata...

    Afroditi-Despina Lalou, Marek Czosnyka, Zofia H. Czosnyka in Acta Neurochirurgica (2020)

  11. Article

    Open Access

    Cerebrospinal fluid dynamics in pediatric pseudotumor cerebri syndrome

    There is a growing body of evidence highlighting the importance of comprehensive intracranial pressure (ICP) values in pseudotumor cerebri syndrome (PTCS). Due to the highly dynamic nature of ICP, several meth...

    Afroditi-Despina Lalou, James S. McTaggart, Zofia H. Czosnyka in Child's Nervous System (2020)

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    Living Reference Work Entry In depth

    Cerebrospinal Fluid Pressure Dynamics

    Although hydrocephalus is much more than CSF dynamics disorder, components of disturbed CSF circulation and volume-pressure compensation are omnipotent in almost all types of this disease. CSF infusion test or...

    Marek Czosnyka, Martin U. Schuhmann, Zofia H. Czosnyka in Pediatric Hydrocephalus

  13. No Access

    Reference Work Entry In depth

    Cerebrospinal Fluid Pressure Dynamics

    Although hydrocephalus is much more than CSF dynamics disorder, components of disturbed CSF circulation and volume-pressure compensation are omnipotent in almost all types of this disease. CSF infusion test or...

    Marek Czosnyka, Martin U. Schuhmann, Zofia H. Czosnyka in Pediatric Hydrocephalus (2019)

  14. Article

    Brain pulsations enlightened

    Olivier Balédent, Marek Czosnyka, Zofia H. Czosnyka in Acta Neurochirurgica (2018)

  15. Article

    Overdrainage of cerebrospinal fluid and hydrocephalus shunts

    Marek Czosnyka, Zofia H. Czosnyka in Acta Neurochirurgica (2017)

  16. No Access

    Chapter

    Shunt Testing In Vivo: Observational Study of Problems with Ventricular Catheter

    Most shunt obstructions happen at the inlet of the ventricular catheter. Three hundred six infusion studies from 2007 to 2011 were classified as having a typical pattern of either proximal occlusion or patency...

    Zofia H. Czosnyka, Rohitiwa Sinha in Intracranial Pressure and Brain Monitoring… (2016)

  17. No Access

    Chapter

    Waveform Analysis of Intraspinal Pressure After Traumatic Spinal Cord Injury: An Observational Study (O-64)

    Following a traumatic brain injury (TBI), intracranial pressure (ICP) increases, often resulting in secondary brain insults. After a spinal cord injury, here the cord may be swollen, leading to a local increas...

    Marek Czosnyka PhD, Georgios V. Varsos in Intracranial Pressure and Brain Monitoring… (2016)

  18. Article

    Open Access

    Investigation of the hydrodynamic properties of a new MRI-resistant programmable hydrocephalus shunt

    The Polaris valve is a newly released hydrocephalus shunt that is designed to drain cerebrospinal fluid (CSF) from the brain ventricles or lumbar CSF space. The aim of this study was to bench test the properti...

    David M Allin, Marek Czosnyka, Hugh K Richards in Cerebrospinal Fluid Research (2008)

  19. Article

    Open Access

    In vitro hydrodynamic properties of the Miethke proGAV hydrocephalus shunt

    Adjustable shunts are very popular in the management of hydrocephalus and are believed to help in minimizing the number of surgical revisions. The drawback with almost all constructions is that they may be acc...

    David M Allin, Zofia H Czosnyka, Marek Czosnyka in Cerebrospinal Fluid Research (2006)

  20. No Access

    Chapter

    Cerebrospinal Fluid Dynamics

    Historically, the saga of cerebrospinal fluid (CSF) dynamics almost always starts with the Monro-Kellie doctrine. This states that the sum of volumes of brain, blood and CSF (although in the time of Kellie, i....

    Marek Czosnyka, Zofia H. Czosnyka, Peter C. Whitfield in Pediatric Hydrocephalus (2005)

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