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Article
Open AccessUsing Crash Outcome Data Evaluation System (CODES) to examine injury in front vs. rear-seated infants and children involved in a motor vehicle crash in New York State
In New York State (NYS), motor vehicle (MV) injury to child passengers is a leading cause of hospitalization and emergency department (ED) visits in children aged 0–12 years. NYS laws require appropriate child...
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Chapter
Lower Breakpoint of Intracranial Amplitude-Pressure Relationship in Normal Pressure Hydrocephalus
The relationship between intracranial pulse amplitude (AMP) and mean intracranial pressure (ICP) has been previously described. Generally, AMP increases proportionally to rises in ICP. However, at low ICP a lo...
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Chapter
Global Cerebral Autoregulation, Resistance to Cerebrospinal Fluid Outflow and Cerebrovascular Burden in Normal Pressure Hydrocephalus
Introduction: We previously examined the relationship between global autoregulation pressure reactivity index (PRx), mean arterial blood pressure (ABP), Resistance to cerebral spinal fluid (CSF) outflow (Rout) a...
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Chapter
The Role of Cerebrospinal Fluid Dynamics in Normal Pressure Hydrocephalus Diagnosis and Shunt Prognostication
Background: Over the years, there have been several reports and trials of the resistance to cerebrospinal fluid (CSF) outflow (Rout) in normal pressure hydrocephalus (NPH). This work aimed to revisit the utility...
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Chapter
Single Center Experience in Cerebrospinal Fluid Dynamics Testing
Normal pressure hydrocephalus is more complex than a simple disturbance of the cerebrospinal fluid (CSF) circulation. Nevertheless, an assessment of CSF dynamics is key to making decisions about shunt insertio...
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Chapter
Differences in Cerebrospinal Fluid Dynamics in Posttraumatic Hydrocephalus Versus Atrophy, Including Effect of Decompression and Cranioplasty
Introduction: Challenges in diagnosing post-traumatic hydrocephalus (PTH) have created a need for an accurate diagnostic tool. We aim to report CSF dynamics in PTH and atrophy, along with differences before and ...
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Chapter
Comparison of Assessment for Shunting with Infusion Studies Versus Extended Lumbar Drainage in Suspected Normal Pressure Hydrocephalus
Introduction: Tools available for diagnosis of normal pressure hydrocephalus (NPH) and prediction of shunt-response are overnight ICP monitoring, infusion studies, and extended lumbar drainage (ELD). We investig...
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Article
Open AccessCerebrospinal fluid dynamics in non-acute post-traumatic ventriculomegaly
Post-traumatic hydrocephalus (PTH) is potentially under-diagnosed and under-treated, generating the need for a more efficient diagnostic tool. We aim to report CSF dynamics of patients with post-traumatic vent...
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Article
Value of computerized shunt infusion study in assessment of pediatric hydrocephalus shunt function—a two center cross-sectional study
Hydrocephalus shunt malfunction can—also in children—occur insidiously without clear symptoms of raised intracranial pressure (ICP) or changes in ventricular size, imposing a diagnostic challenge. Computerized...
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Article
Open AccessThresholds for identifying pathological intracranial pressure in paediatric traumatic brain injury
Intracranial pressure (ICP) monitoring forms an integral part of the management of severe traumatic brain injury (TBI) in children. The prediction of elevated ICP from imaging is important when deciding on whe...
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Article
Validation of Davson’s equation in patients suffering from idiopathic normal pressure hydrocephalus
The so-called Davson’s equation relates baseline intracranial pressure (ICP) to resistance to cerebrospinal fluid outflow (Rout), formation of cerebrospinal fluid (If) and sagittal sinus pressure (PSS) There is a...
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Chapter and Conference Paper
Are Slow Waves of Intracranial Pressure Suppressed by General Anaesthesia?
Objectives: Slow waves of intracranial pressure (ICP) are spontaneous oscillations with a frequency of 0.3–4 cycles/min. They are often associated with pathological conditions, following vasomotor activity in th...
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Chapter and Conference Paper
Is There a Link Between ICP-Derived Infusion Test Parameters and Outcome After Shunting in Normal Pressure Hydrocephalus?
Objective: The term “hydrocephalus” encompasses a range of disorders characterised by clinical symptoms, abnormal brain imaging and derangement of cerebrospinal fluid (CSF) dynamics. The ability to elucidate whi...
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Chapter
Shunt Testing In Vivo: Observational Study of Problems with Ventricular Catheter
Most shunt obstructions happen at the inlet of the ventricular catheter. Three hundred six infusion studies from 2007 to 2011 were classified as having a typical pattern of either proximal occlusion or patency...
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Article
Open AccessAre B waves of intracranial pressure suppressed by general anesthesia?
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Article
Open AccessNon-invasive assessment of ICP during infusion test using Transcranial Doppler Ultrasonography
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Article
Open AccessRelationship between CSF dynamics and outcome after shunting in NPH- 20 years of single centre experience
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Chapter
Hydrocephalus
Hydrocephalus is defined as the abnormal accumulation of cerebrospinal fluid (CSF), within all or part of the ventricular system, which is currently, or has been, at an abnormally high pressure. The increased ...
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Article
Epilepsy associated with shaken baby syndrome
The shaken baby syndrome (SBS) is an important cause of developmental delay in infants. Epileptic seizures are a common feature of this syndrome. The aim if this study is to analyse the impact of the early and...
