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Article
Open AccessExtracellular vesicles from UTX-knockout endothelial cells boost neural stem cell differentiation in spinal cord injury
Vascular endothelial cells are pivotal in the pathophysiological progression following spinal cord injury (SCI). The UTX (Ubiquitously Transcribed Tetratripeptide Repeat on Chromosome X) serves as a significan...
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Article
Open AccessInhibition of UTX/KDM6A improves recovery of spinal cord injury by attenuating BSCB permeability and macrophage infiltration through the MLCK/p-MLC pathway
Spinal cord injury (SCI) can prompt an immediate disruption to the blood–spinal cord barrier (BSCB). Restoring the integrity of this barrier is vital for the recovery of neurological function post-SCI. The UTX...
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Article
Open AccessUTX deletion promotes M2 macrophage polarization by epigenetically regulating endothelial cell-macrophage crosstalk after spinal cord injury
Macrophages polarized to the M2 subtype after spinal cord injury (SCI) are beneficial for promoting neurological recovery. The crosstalk between endothelial cells (ECs) and macrophages is crucial for the imbal...
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Chapter and Conference Paper
Enhancing Adversarial Transferability from the Perspective of Input Loss Landscape
The transferability of adversarial examples enables the black-box attacks and poses a threat to the application of deep neural networks in real-world, which has attracted great attention in recent years. Regar...
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Chapter and Conference Paper
UIA-ViT: Unsupervised Inconsistency-Aware Method Based on Vision Transformer for Face Forgery Detection
Intra-frame inconsistency has been proved to be effective for the generalization of face forgery detection. However, learning to focus on these inconsistency requires extra pixel-level forged location annotati...
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Article
Open AccessA topology-preserving dimensionality reduction method for single-cell RNA-seq data using graph autoencoder
Dimensionality reduction is crucial for the visualization and interpretation of the high-dimensional single-cell RNA sequencing (scRNA-seq) data. However, preserving topological structure among cells to low di...
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Article
Open AccessA combinatorial method to visualize the neuronal network in the mouse spinal cord: combination of a modified Golgi-Cox method and synchrotron radiation micro-computed tomography
Exploring the three-dimensional (3D) morphology of neurons is essential to understanding spinal cord function and associated diseases comprehensively. However, 3D imaging of the neuronal network in the broad r...
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Article
Open AccessThe protective effect of microRNA-21 in neurons after spinal cord injury
Experimental animal study.
