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Article
Compressed Least Squares Algorithm of Continuous-Time Linear Stochastic Regression Model Using Sampling Data
In this paper, the authors consider a sparse parameter estimation problem in continuous-time linear stochastic regression models using sampling data. Based on the compressed sensing (CS) method, the authors pr...
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Article
Correction: HDAC1 Promotes Mitochondrial Pathway Apoptosis and Inhibits the Endoplasmic Reticulum Stress Response in High Glucose-Treated Schwann Cells via Decreased U4 Spliceosomal RNA
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Article
Open AccessSHR-A1811 (antibody-drug conjugate) in advanced HER2-mutant non-small cell lung cancer: a multicenter, open-label, phase 1/2 study
A dose-escalation and expansion, phase 1/2 study (ClinicalTrials.gov, NCT04818333) was conducted to assess the novel antibody-drug conjugate SHR-A1811 in pretreated HER2-altered advanced non-small cell lung ca...
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Article
Open AccessEGFR mutations induce the suppression of CD8+ T cell and anti-PD-1 resistance via ERK1/2-p90RSK-TGF-β axis in non-small cell lung cancer
Non-small cell lung cancer (NSCLC) patients with EGFR mutations exhibit an unfavorable response to immune checkpoint inhibitor (ICI) monotherapy, and their tumor microenvironment (TME) is usually immunosuppressed...
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Article
Open AccessThe value of deep learning-based X-ray techniques in detecting and classifying K-L grades of knee osteoarthritis: a systematic review and meta-analysis
Knee osteoarthritis (KOA), a prevalent degenerative joint disease, is primarily diagnosed through X-ray imaging. The Kellgren-Lawrence grading system (K-L) is the gold standard for evaluating KOA severity thro...
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Article
Causal impact of statins on susceptibility to osteoarthritis: insights from a two-sample Mendelian randomization analysis
Osteoarthritis is a widely prevalent cause of pain and disability among older adults. It is an incurable condition, and most treatments are aimed at alleviating symptoms.
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Article
Reducing Hyperexponential Functions over Monomial Extensions
The authors extend the shell and kernel reductions for hyperexponential functions over the field of rational functions to a monomial extension. Both of the reductions are incorporated into one algorithm. As an...
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Article
Open AccessAgreement and repeatability of scotopic pupil size measurement with the 2WIN-S portable refractor in Chinese adults
To assess the agreement and repeatability of scotopic pupil size measurement using 2WIN-S (Adaptica, Padova, Italy) portable refractor in Chinese adults. This prospective non-randomized open-label controlled ...
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Article
Open AccessCausal relationship between bone mineral density and intervertebral disc degeneration: a univariate and multivariable mendelian randomization study
Although previous studies have suggested a possible association between bone mineral density (BMD) and intervertebral disc degeneration (IDD), the causal relationship between them remains unclear. Evidence fro...
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Article
Open AccessResearch progress and prospects of benefit-risk assessment methods for umbilical cord mesenchymal stem cell transplantation in the clinical treatment of spinal cord injury
Over the past decade, we have witnessed the development of cell transplantation as a new strategy for repairing spinal cord injury (SCI). However, due to the complexity of the central nervous system (CNS), ach...
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Article
Mechanism study and acoustic field simulation of high-energy ultrasonic vibration agitation for the preparation of cement slurry
The acoustic field calculation model of ultrasonic vibration-mixed cement slurry is established to investigate the preparation and optimization process of the slurry as well as to study the dispersion mechanis...
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Article
Open AccessA prognostic nomogram to predict the cancer-specific survival of patients with initially diagnosed metastatic gastric cancer: a validation study in a Chinese cohort
Few studies have been designed to predict the survival of Chinese patients initially diagnosed with metastatic gastric cancer (mGC). Therefore, the objective of this study was to construct and validate a new n...
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Article
HDAC1 Promotes Mitochondrial Pathway Apoptosis and Inhibits the Endoplasmic Reticulum Stress Response in High Glucose-Treated Schwann Cells via Decreased U4 Spliceosomal RNA
Dysfunction of Schwann cells, including cell apoptosis, autophagy inhibition, dedifferentiation, and pyroptosis, is a pivotal pathogenic factor in induced diabetic peripheral neuropathy (DPN). Histone deacetyl...
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Article
Genetic influence of meningioma on cisplatin resistance: a Mendelian randomization analysis
Although various aspects of cisplatin resistance have been studied, the impact of genetic variations still needs to be explored.
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Article
Open AccessLaser therapy for treating cleft lip or/and palate scarring—a systematic review and meta-analysis
This review aims to assess the efficacy and safety of laser therapy in managing scars resulting from cleft lip and/or palate (CL/P) repair surgeries, as well as to determine the optimal timing for intervention...
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Article
ZMNet: feature fusion and semantic boundary supervision for real-time semantic segmentation
Feature fusion module is an essential component of real-time semantic segmentation networks to bridge the semantic gap among different feature layers. However, many networks are inefficient in multi-level feat...
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Article
Event-triggered optimal tracking control for strict-feedback nonlinear systems with non-affine nonlinear faults
This article studies the control ideas of the optimal backstep** technique, proposing an event-triggered optimal tracking control scheme for a class of strict-feedback nonlinear systems with non-affine and n...
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Article
RNF144A-AS1 stabilizes TAF15 and promotes malignant biological behaviors of skin cutaneous melanoma
LncRNAs have been demonstrated to regulate biological processes in malignant tumors. In our previous study, we identified the immune-related LncRNA RNF144A-AS1 as a potential regulator in SKCM. However, its pr...
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Article
YOLOv8n-LSLW: a lightweight method for real-time detection of wild fishing behavior
With the development of the electric power industry, the laying of transmission lines covers various waters, which poses a great threat to the life safety of fishermen who intrude into high-voltage areas. To a...
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Article
Open AccessEvaluation of postoperative complications of hypospadias using high-frequency ultrasound imaging
Various complications following hypospadias surgery present distinct manifestations when examined with ultrasound. Utilizing high-frequency ultrasound, clinicians can promptly identify these complications and ...
