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Article
Open AccessCorrection: Sirt1 coordinates with ERα to regulate autophagy and adiposity
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Chapter and Conference Paper
Measurement and Application of Industrial Robot Jitter
Industrial robots are widely used in automobile and auto parts manufacturing, mechanical processing industry, electronic and electrical industry, rubber and plastic industry and many other critical areas. The ...
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Protocol
Assessing the Activity of Transcription Factor FoxO1
The transcription factor FoxO1 (forkhead box O1) regulates genes that are involved in development, metabolism, cellular innovation, longevity, and stress responses. Assessment of FoxO1 activity is therefore cr...
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Article
Open AccessControllable synthesis of conjugated microporous polymer films for ultrasensitive detection of chemical warfare agents
Nerve agents, one of the most toxic chemical warfare agents, seriously threaten human life and public security. The high toxicity of nerve agents makes the development of fluorescence sensors with suitable lim...
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Article
Assessing learning engagement based on facial expression recognition in MOOC’s scenario
Online learning has become one of the most important learning styles, yet with the need of supervisors to consistently keep the learners motivated and on-task. Some learners could be supervised by outer factor...
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Chapter
Backward Designing a Lab Course to Promote Authentic Research Experience According to Students’ Gains in Research Abilities
The consensus among educators across the science disciplines is for undergraduate education to include authentic research and scientific practices in science, technology, engineering, and mathematics courses. ...
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Article
Open AccessSirt1 coordinates with ERα to regulate autophagy and adiposity
Sex difference in adiposity has long been recognized but the mechanism remains incompletely understood. Previous studies suggested that adiposity was regulated by autophagy in response to energy status change....
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Article
Obesity-associated inflammation induces androgenic to estrogenic switch in the prostate gland
Our patient cohort revealed that obesity is strongly associated with steroid-5α reductase type 2 (SRD5A2) promoter methylation and reduced protein expression. The underlying mechanism of prostatic growth in this ...
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Article
Electrochemical and Tribological Properties of CrAlN, TiAlN, and CrTiN Coatings in Water-Based Cutting Fluid
CrAlN, TiAlN, CrTiN coatings were prepared using magnetron sputtering system. The mechanical and tribological properties of the coatings were investigated. TiAlN coating showed the highest nanohardness of 16.1...
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Protocol
Autophagy in Adipocyte Differentiation
Adipose tissue regulates metabolic homeostasis by acting as an endocrine organ and energy reservoir. Adipose tissue development and functional maintenance are dependent on adipocyte differentiation, in which a...
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Article
Music auto-tagging based on the unified latent semantic modeling
We proposed a music auto-tagging approach based on the latent space modeling both for music context and content. First, we introduce the latent semantic analysis for music tags with Sparse Nonnegative Matrix F...
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Article
Open AccessEstradiol signaling mediates gender difference in visceral adiposity via autophagy
Excessive adiposity (particularly visceral fat mass) increases the risks of develo** metabolic syndrome. Women have lower deposit of visceral fat than men, and this pattern becomes diminished postmenopausall...
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Chapter
Forkhead Box O (FoxO) Transcription Factors in Autophagy, Metabolic Health, and Tissue Homeostasis
As transcription factors, the forkhead box O family proteins control the expression of genes that are involved in the regulation of autophagy and metabolism. The FoxO–autophagy axis has been shown to mediate c...
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Protocol
Isolation of Mouse Stromal Vascular Cells for Monolayer Culture
Positive energy balance contributes to adipose tissue expansion and dysfunction, which accounts largely for obesity and related metabolic disorders. Thermogenic fat can dissipate energy, activation or inductio...
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Chapter and Conference Paper
Multi-Task Multi-modal Semantic Hashing for Web Image Retrieval with Limited Supervision
As an important element of social media, social images become more and more important to our daily life. Recently, smart hashing scheme has been emerging as a promising approach to support fast social image se...
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Article
Open AccessGPR30 regulates diet-induced adiposity in female mice and adipogenesis in vitro
Recent studies showed that GPR30, a seven-transmembrane G-protein-coupled receptor, is a novel estrogen receptor (ER) that mediates some biological events elicited by estrogen in several types of cancer cells....
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Article
Open AccessFoxO1 interacts with transcription factor EB and differentially regulates mitochondrial uncoupling proteins via autophagy in adipocytes
Mitochondrial uncoupling proteins (UCPs) are inducible and play an important role in metabolic and redox homeostasis. Recent studies have suggested that FoxO1 controls mitochondrial biogenesis and morphology, ...
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Article
The effects of multiple query evidences on social image retrieval
System performance assessment and comparison are fundamental for large-scale image search engine development. This article documents a set of comprehensive empirical studies to explore the effects of multiple ...
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Article
Open AccessInsulin resistance is associated with epigenetic and genetic regulation of mitochondrial DNA in obese humans
Mitochondrial alterations have been observed in subjects with metabolic disorders such as obesity and diabetes. Studies on animal models and cell cultures suggest aberrant glucose and lipid levels, and impaire...
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Chapter and Conference Paper
The Evolution of Research on Multimedia Travel Guide Search and Recommender Systems
The importance of multimedia travel guide search and recommender systems has led to a substantial amount of research spanning different computer science and information system disciplines in recent years. The ...