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  1. No Access

    Chapter and Conference Paper

    TrieKV: Managing Values After KV Separation to Optimize Scan Performance in LSM-Tree

    Persistent key-value(KV) stores are mainly designed based on the Log-Structured Merge-tree(LSM-tree) for high write performance, yet the LSM-tree suffers from the inherently high I/O amplification which influe...

    Zekun Yao, Yang Song, Yinliang Yue, **zhou Liu, Zhixin Fan in Web and Big Data (2024)

  2. No Access

    Chapter and Conference Paper

    HTStore: A High-Performance Mixed Index Based Key-Value Store for Update-Intensive Workloads

    In this paper, we propose a high-performance Mixed Index based key-value store named HTStore to improve the write and read performance in update-intensive workloads of LSM-tree based key-value stores. The key ...

    **zhou Liu, Yinliang Yue, Jiang Zhou, Zhixin Fan, Zekun Yao in Web and Big Data (2024)

  3. No Access

    Chapter and Conference Paper

    LayerBF: A Space Allocation Policy for Bloom Filter in LSM-Tree

    LSM-Tree based key-value stores commonly suffer from the issue of read amplification, as the retrieval of a particular key typically requires examination of multiple layers of SSTables. To enhance query perfor...

    Jiaoyang Li, Zhixin Fan, Yinliang Yue, Zekun Yao, **zhou Liu in Web and Big Data (2024)

  4. Article

    Open Access

    Causal relationships between blood lipids and major psychiatric disorders: Univariable and multivariable mendelian randomization analysis

    Whether the positive associations of blood lipids with psychiatric disorders are causal is uncertain. We conducted this two-sample Mendelian randomization (MR) analysis to comprehensively investigate associati...

    Bozhi Li, Yue Qu, Zhixin Fan, **ayu Gong, Hanfang Xu, Lili Wu in BMC Medical Genomics (2023)

  5. Article

    Open Access

    The superposition effects of air pollution on government health expenditure in China— spatial evidence from GeoDetector

    As the fifth-largest global mortality risk factor, air pollution has caused nearly one-tenth of the world’s deaths, with a death toll of 5 million. 21% of China’s disease burden was related to environmental po...

    Qi **a, **yu Zhang, Yanmin Hu, Wanxin Tian, Wenqing Miao, Bing Wu in BMC Public Health (2022)

  6. No Access

    Article

    Artemisinin suppresses myocardial ischemia–reperfusion injury via NLRP3 inflammasome mechanism

    Artemisinin is known for its pharmaceutical effect against malaria and received increased attention for its other potential function. Mounting evidence suggest that artemisinin could also exert cardioprotectiv...

    Fengyue Wang, Qian** Gao, **g Yang, Can Wang in Molecular and Cellular Biochemistry (2020)

  7. No Access

    Article

    Dynamic Analysis of Planetary Gear Transmission System Considering the Flexibility of Internal Ring Gear

    A rigid-flexible coupled dynamic model of the planetary gear transmission system was developed considering the flexibility of the internal ring gear (flexible internal ring gear) and the sun shaft based on the...

    Zhixin Fan, Caichao Zhu, Chaosheng Song in Iranian Journal of Science and Technology,… (2020)

  8. No Access

    Article

    Porcine circovirus type 2 ORF5 protein induces endoplasmic reticulum stress and unfolded protein response in porcine alveolar macrophages

    Porcine circovirus type 2 (PCV2) is the essential infectious agent causing porcine circovirus-associated disease (PCVD) in pigs and one of the important viruses that severely jeopardize the swine husbandry ind...

    Yueling Ouyang, Lei Xu, Jiangman Lv, Yufeng Hou, Zhixin Fan in Archives of Virology (2019)

  9. Article

    Open Access

    Protective effect of hydrogen-rich saline on pressure overload-induced cardiac hypertrophyin rats: possible role of JAK-STAT signaling

    Molecular hydrogen has been shown to have antioxidant effect and have been used to prevent oxidative stress-related diseases. The goal of this study was to explore if hydrogen-rich saline (HRS) plays a cardiop...

    Zhixin Fan, Yufei Gao, Zhiwei Huang, Fenghua Xue in BMC Cardiovascular Disorders (2018)