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    Chapter

    P450—mediated Insecticide Detoxification and Its Implication in Insecticide Efficacy

    Insecticides have been extensively used to control insect pests that transmit human diseases and damage our crops by feeding or indirectly by transmitting plant diseases. However, insect pests still pose serio...

    Zhimou Wen, **ng Zhang, Yalin Zhang in Recent Advances in Entomological Research (2011)

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    Article

    Enhanced Toxicity and Induction of Cytochrome P450s Suggest a Cost of “Eavesdrop**” in a Multitrophic Interaction

    The inducibility of cytochrome P450 monooxygenases (P450s) and other xenobiotic-metabolizing enzymes is thought to reflect material and energy costs of biosynthesis. Efforts to detect such costs of detoxificat...

    Ren Sen Zeng, Zhimou Wen, Guodong Niu, Mary A. Schuler in Journal of Chemical Ecology (2009)

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    Article

    Ecological Significance of Induction of Broad-Substrate Cytochrome P450s by Natural and Synthetic Inducers in Helicoverpa zea

    The polyphagous corn earworm Helicoverpa zea relies on cytochrome P450 monooxygenases with broad substrate specificities to cope with the wide diversity of phytochemicals it encounters among its numerous host pla...

    Zhimou Wen, Ren Sen Zeng, Guodong Niu, May R. Berenbaum in Journal of Chemical Ecology (2009)

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    Article

    Allelochemical Induction of Cytochrome P450 Monooxygenases and Amelioration of Xenobiotic Toxicity in Helicoverpa zea

    Polyphagous herbivores encounter allelochemicals as complex mixtures in their host plants, and the toxicity of an individual compound may be influenced by the chemical matrix in which it is encountered. Certai...

    Ren Sen Zeng, Zhimou Wen, Guodong Niu, Mary A. Schuler in Journal of Chemical Ecology (2007)

  5. Article

    Toxicity of Aflatoxin B1 to Helicoverpa zea and Bioactivation by Cytochrome P450 Monooxygenases

    Ren Sen Zeng, Guodong Niu, Zhimou Wen, Mary A. Schuler in Journal of Chemical Ecology (2007)

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    Article

    Toxicity of Aflatoxin B1 to Helicoverpa zea and Bioactivation by Cytochrome P450 Monooxygenases

    Infestation of corn (Zea mays) by corn earworm (Helicoverpa zea) predisposes the plant to infection by Aspergillus fungi and concomitant contamination with the carcinogenic mycotoxin aflatoxin B1 (AFB1). Although...

    Ren Sen L. Zeng, Guodong Niu, Zhimou Wen, Mary A. Schuler in Journal of Chemical Ecology (2006)

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    Article

    Inhibition of CYP6B1-Mediated Detoxification of Xanthotoxin by Plant Allelochemicals in the Black Swallowtail (Papilio polyxenes)

    The structural and biosynthetic diversity of allelochemicals in plants is thought to arise from selection for additive toxicity as a consequence of toxin mixture or for enhanced toxicity as a result of synergi...

    Zhimou Wen, May R. Berenbaum, Mary A. Schuler in Journal of Chemical Ecology (2006)