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Article
Correction: Characteristics and evaluation of C1 posterior arch variation for transpedicular screw placement between patients with and without basilar invagination
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Article
Harnessing 3D in vitro systems to model immune responses to solid tumours: a step towards improving and creating personalized immunotherapies
In vitro 3D models are advanced biological tools that have been established to overcome the shortcomings of oversimplified 2D cultures and mouse models. Various in vitro 3D immuno-oncology models have been dev...
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Article
Multi-Parameter Influence Analysis of Interaction Between Internal Solitary Wave and Fixed Submerged Body
To obtain the interaction characteristics between Internal solitary waves (ISWs) and submerged bodies, a three-dimensional numerical model for simulating ISWs was established in the present study based on the ...
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Article
Transglutaminases are oncogenic biomarkers in human cancers and therapeutic targeting of TGM2 blocks chemoresistance and macrophage infiltration in pancreatic cancer
Transglutaminases (TGs) are multifunctional enzymes exhibiting transglutaminase crosslinking, as well as atypical GTPase/ATPase and kinase activities. Here, we used an integrated comprehensive analysis to asse...
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Article
Characteristics and evaluation of C1 posterior arch variation for transpedicular screw placement between patients with and without basilar invagination
C1 transpedicular screw (C1TS) placement provided satisfactory pullout resistance and 3D stability, but its application might be limited in patients with basilar invagination (BI) due to the high incidences of...
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Article
The SLITRK4-CNPY3 axis promotes liver metastasis of gastric cancer by enhancing the endocytosis and recycling of TrkB in tumour cells
Gastric cancer (GC) is a malignant tumour with high mortality, and liver metastasis is one of the main causes of poor prognosis. SLIT- and NTRK-like family member 4 (SLITRK4) plays an important role in the ner...
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Article
Dipyridamole enhances the anti-cancer ability of aspirin against colorectal cancer by inducing apoptosis in an unfolded protein response-dependent manner
Available evidence indicates that dipyridamole enhances the anti-thrombotic effects of aspirin for the prevention of secondary strokes. Aspirin is a well-known non-steroid anti-inflammatory drug. This anti-inf...
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Article
Open AccessCoadaptation fostered by the SLIT2-ROBO1 axis facilitates liver metastasis of pancreatic ductal adenocarcinoma
To explore the mechanism of coadaptation and the potential drivers of pancreatic ductal adenocarcinoma (PDAC) metastasis to the liver, we study key molecules involved in this process and their translational va...
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Article
Sb nanoparticles encapsulated in N-doped carbon nanotubes as freestanding anodes for high-performance lithium and potassium ion batteries
Sb-based materials with high specific capacity have targeted as an alternative anode material for alkali metal ion batteries. Herein, Sb nanoparticles embedded in hollow porous N-doped carbon nanotubes (Sb@N-C...
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Article
The genomic, transcriptomic, and immunological profiles of perineural invasion in pancreatic ductal adenocarcinoma
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Article
Distributed energy-efficient clustering routing protocol for wireless sensor networks using affinity propagation and fuzzy logic
Organizing nodes into clusters and forwarding data to the base station (BS) in clustering routing protocols have been widely utilized to improve the energy efficiency, scalability and stability of wireless sen...
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Article
A low amino acid environment promotes cell macropinocytosis through the YY1-FGD6 axis in Ras-mutant pancreatic ductal adenocarcinoma
Pancreatic ductal adenocarcinoma (PDAC), cancer with a high mortality rate and the highest rate of KRAS mutation, reportedly internalizes proteins via macropinocytosis to adapt to low amino acid levels in the tum...
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Chapter and Conference Paper
The Characterization of the Pre-carboniferous Karst Paleogeomorphology and Its Control on Ma5_(1+2) Reservoirs in the Middle Area of Sulige Gas Field
Closely combined with the exploration and development, based on drilling data, logging data, seismic data and so on, the weathering crust of Ordovician in Western Erdos basin was taken as the object, guided by...
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Chapter and Conference Paper
Distribution Types of Remaining Reserves in Strongly Heterogeneous and Compact Sandstone Gas Reservoirs and Technical Development Strategies
Sulige gas field is a typical representative of strong heterogeneous tight sandstone gas reservoirs in China. Its reserves are abundant. With the development of the gas field, all the development blocks under ...
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Article
CTHRC1 promotes liver metastasis by resha** infiltrated macrophages through physical interactions with TGF-β receptors in colorectal cancer
Metastasis is a major cause of cancer-related deaths. Tumor-intrinsic properties can determine whether tumor metastasis occurs or not. Here, by comparing the gene expression patterns in primary colorectal canc...
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Article
Open AccessSingle-cell RNA sequencing reveals that targeting HSP90 suppresses PDAC progression by restraining mitochondrial bioenergetics
Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest cancers, which lacks effective treatment strategies. There is an urgent need for the development of new strategies for PDAC therapy. The genetic ...
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Article
Open AccessIdentification of a subset of immunosuppressive P2RX1-negative neutrophils in pancreatic cancer liver metastasis
The immunosuppressive microenvironment that is shaped by hepatic metastatic pancreatic ductal adenocarcinoma (PDAC) is essential for tumor cell evasion of immune destruction. Neutrophils are important componen...
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Article
Open AccessAn alternative approach to match field production data from unconventional gas-bearing systems
Nowadays, the unconventional gas-bearing system plays an increasingly important role in energy market. The performances of the current history-matching techniques are not satisfied when applied to such systems...
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Article
Open AccessCorrection to: Platelets promote breast cancer cell MCF-7 metastasis by direct interaction: surface integrin α2β1-contacting-mediated activation of Wnt-β-catenin pathway
An amendment to this paper has been published and can be accessed via the original article.
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Article
LaCoO3-modified RuO2–TiO2/Ti electrode as an efficient electrocatalyst for oxygen evolution reaction
A RuO2–TiO2/Ti electrode modified with LaCoO3 was successfully fabricated by thermal decomposition and its electrochemical properties were evaluated by cyclic voltammetry (CV), electrochemical impedance spectrosc...
