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Article
Open AccessStructure and genome editing of type I-B CRISPR-Cas
Type I CRISPR-Cas systems employ multi-subunit effector Cascade and helicase-nuclease Cas3 to target and degrade foreign nucleic acids, representing the most abundant RNA-guided adaptive immune systems in prok...
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Article
Remodel the perifollicular microenvironment via Minoxidil-loaded microneedle patch and cold atmospheric plasma for treating androgenetic alopecia
Androgenetic alopecia (AGA) is a chronic and progressive form of hair loss characterized by vascular degeneration in the perifollicular microenvironment, leading to cell apoptosis and eventual loss of hair fol...
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Article
Open AccessO-sialoglycoprotein Endopeptidase (OSGEP) Suppresses Hepatic Ischemia-Reperfusion Injury-Induced Ferroptosis Through Modulating the MEK/ERK Signaling Pathway
Hepatic ischemia–reperfusion injury (HIRI) was widely accepted as a critical complication of liver resection and transplantation. A growing body of evidence suggested that O-sialoglycoprotein endopeptidase (OS...
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Article
Open AccessElevated peripheral levels of receptor-interacting protein kinase 1 (RIPK1) and IL-8 as biomarkers of human amyotrophic lateral sclerosis
Amyotrophic lateral sclerosis (ALS) is a devastating fatal neurodegenerative disease with no cure. Receptor-interacting protein kinase 1 (RIPK1) has been proposed to mediate pathogenesis of ALS. Primidone has ...
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Article
Open AccessA modified chain-based sponge dressing controls junctional hemorrhage in the tactical combat casualty care simulation of pigs
Hemorrhage has always been the focus of battlefield and pre-hospitalization treatment. With the increasing fatality rates associated with junctional bleeding, treatment of bleeding at junctional sites has grad...
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Article
Parental psychological and behavioral control and positive youth development among young Chinese adolescents: The mediating role of basic psychological needs satisfaction
Previous studies indicate that parental psychological control and behavioral control play crucial roles in the positive development of adolescents. However, little is known about the underlying mechanism of th...
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Article
Advances in graphene oxide membranes for water treatment
Graphene oxide (GO), a derivative of graphene, is a novel carbon material that has attracted a lot of attention in the field of membrane materials as its ability to achieve layer-by-layer stacking and the form...
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Article
Fully self-powered instantaneous wireless liquid level sensor system based on triboelectric nanogenerator
Self-powered sensors are highly sought for wireless sensing applications in space exploration, industries, and environmental monitoring, etc. However, most current self-powered sensor technologies are based on...
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Article
Open AccessThe burden of aortic aneurysm in China from 1990 to 2019: findings from the Global Burden of Disease Study 2019
Aortic aneurysm (AA) is a global public health concern. However, little is known about the disease burden of AA in China.
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Article
Open AccessComparison of growth performance among channel-blue hybrid catfish, ccGH transgenic channel catfish, and channel catfish in a tank culture system
Fish is an essential source of high-quality protein for people worldwide. The present study was designed to compare the growth performance among the channel-blue hybrid catfish, channel catfish transgenic for ...
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Chapter and Conference Paper
Studies on the Temperature Characteristics of an Ultrasonic Atomization Feed Direct Methanol Fuel Cell
Direct methanol fuel cell (DMFC) is the most promising portable energy device to replace traditional lithium cell. However, the development of DMFC is limited by methanol crossover (MCO) and product management...
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Chapter and Conference Paper
Numerical Study on Seismic Behavior of Shield Tunnel Crossing Saturated Sand Strata with Different Densities
This study investigated the seismic response of a shield tunnel crossing two saturated sand stratums with different relative densities using a finite difference method. A bounding surface plasticity model was ...
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Article
Growth Differences of Growth Hormone Transgenic Female and Male Channel Catfish, Ictalurus punctatus, Grown in Earthen Ponds to Sexual Maturation
This study compared growth performance between female and male transgenic channel catfish, Ictalurus punctatus, containing channel catfish growth hormone full-length cDNA driven by the ocean pout antifreeze prote...
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Article
Green-synthesized nanosize Mont-supported Fe0 via tea extract for enhanced transport and in situ remediation of Pb(II) in soil
Lead (Pb(II)) can be accumulated in soil and transferred to humans via the food chain. Therefore, it is essential to improve Pb(II) immobilization during soil remediation.
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Article
Direct and pleiotropic effects of the Masou Salmon Delta-5 Desaturase transgene in F1 channel catfish (Ictalurus punctatus)
Channel catfish (Ictalurus punctatus) is the primary culture species in the US along with its hybrid made with male blue catfish, I. furcatus. In an effort to improve the nutritional value of channel catfish, the...
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Article
Comparative Genomic and Transcriptomic Analyses Revealed Twenty-Six Candidate Genes Involved in the Air-Breathing Development and Function of the Bighead Catfish Clarias macrocephalus
The bighead catfish (Clarias macrocephalus) and channel catfish (Ictalurus punctatus) are freshwater species in the Siluriformes order. C. macrocephalus has both gills and modified gill structures serving as an a...
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Article
Effect of humic acid on the sedimentation and transport of nanoparticles silica in water-saturated porous media
Nano silicon particles (nSiO2) is one of the most widely used industrial engineered nanomaterials (ENMs). The extensive applications of nSiO2 may pose potential risks to aquatic ecosystems and human health. Humic...
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Chapter and Conference Paper
Non-directional Learning Strategy Particle Swarm Optimization Algorithm
In conventional particle swarm optimization (PSO) algorithm, each particle adjusts their position and velocity to achieve an optimal solution by iteration, but it has the tendency to fall into the local optimu...
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Article
Open AccessEffects of CRISPR/Cas9 dosage on TICAM1 and RBL gene mutation rate, embryonic development, hatchability and fry survival in channel catfish
The current study was conducted to assess the effects of microinjection of different dosages of guide RNA (gRNA)/Cas9 protein on the mutation rate, embryo survival, embryonic development, hatchability and earl...
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Article
Irinotecan Alters the Disposition of Morphine Via Inhibition of Organic Cation Transporter 1 (OCT1) and 2 (OCT2)
The organic cation transporters (OCTs) and multidrug and toxin extrusions (MATEs) together are regarded as an organic cation transport system critical to the disposition and response of many organic cationic d...
