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Article
Monomeric and self-assembled crystal phases of TNBT
(3,3′,5,5′-Tetranitro-4,4′-bi-1,2,4-Triazole) TNBT was designed and predicted more than three decades ago as a high energy material. As with many other designed molecules, TNBT has not been successfully synthe...
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Article
Open AccessGenetically programmable cell membrane-camouflaged nanoparticles for targeted combination therapy of colorectal cancer
Cell membrane-camouflaged nanoparticles possess inherent advantages derived from their membrane structure and surface antigens, including prolonged circulation in the bloodstream, specific cell recognition and...
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Article
Open AccessComprehensive characterization of B7 family members in breast cancer: B7-H5 switch reverses breast cancer from “immuno-cold” into “immuno-hot” status
The members of the classic B7 family regulate the immune microenvironment of several malignant tumors. However, the potential relationship between the B7 family and the breast cancer (BrCa) tumor immune microe...
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Article
Open AccessAn Overview of Coupled Lagrangian–Eulerian Methods for Ocean Engineering
Combining the strengths of Lagrangian and Eulerian descriptions, the coupled Lagrangian–Eulerian methods play an increasingly important role in various subjects. This work reviews their development and applica...
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Article
Is an academic justice climate effective? The moderation role of sensitivity and perceived organizational support on the impact of academic justice climate on innovation performance: a double-intermediary model of spiritual health system
In the realm of innovation, relying solely on the creativity of researchers may not fully unleash their potential. Previous studies revealed the positive impact of academic justice climate on researchers’ beha...
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Article
Cortico-muscular coherence of time–frequency and spatial characteristics under movement observation, movement execution, and movement imagery
Studies show that movement observation (MO), movement imagery (MI), or movement execution (ME) based brain–computer interface systems are promising in promoting the rehabilitation and reorganization of damaged...
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Article
Open AccessLow-Shear Stress Promotes Atherosclerosis via Inducing Endothelial Cell Pyroptosis Mediated by IKKε/STAT1/NLRP3 Pathway
Atherosclerosis is initiated by vascular endothelial dysfunction, and low-shear stress (LSS) of blood flow is a key factor leading to endothelial dysfunction. Growing evidence suggests that endothelial cell py...
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Article
Dissolved oxygen and ammonia affect ammonia production via GDH/AMPK signaling pathway and alter flesh quality in Chinese perch (Siniperca chuatsi)
The dissolved oxygen (DO) and ammonia are crucial to the growth of Chinese perch (Siniperca chuatsi). Information on the effects of DO and total ammonia nitrogen (TAN) in regulating ammonia nitrogen excretion and...
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Article
Open AccessSurface ligand-regulated renal clearance of MRI/SPECT dual-modality nanoprobes for tumor imaging
The general sluggish clearance kinetics of functional inorganic nanoparticles tend to raise potential biosafety concerns for in vivo applications. Renal clearance is a possible elimination pathway for function...
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Article
Preoperative supine pelvic incidence predicts standing pelvic incidence following S2AI fixation in patients with adult spinal deformity: a prospective study
A prospective study.
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Article
Open AccessEliminating sensing blind spots of field-enhanced Rydberg atomic antenna via an asymmetric parallel-plate resonator
Due to its large electric dipole moment, the Rydberg atom exhibits a strong response to weak electric fields, hence it is regarded as a highly promising atomic antenna. However, to enhance the reception sensit...
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Article
Preparation of nylon based magnetic adsorption materials and their adsorption properties for heavy metal ions
Wastewater containing heavy metal ions poses great harm to human health and the environment. The adsorption materials used in traditional adsorption methods, such as starch and cellulose, are prone to hydrolys...
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Article
Open AccessIncreasing the robustness of Escherichia coli for aromatic chemicals production through transcription factor engineering
Engineering microbial cell factories has been widely used to produce a variety of chemicals, including natural products, biofuels, and bulk chemicals. However, poor robustness limits microbial production on an...
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Article
Open AccessMETTL3-mediated RanGAP1 promotes colorectal cancer progression through the MAPK pathway by recruiting YTHDF1
Ran GTPase activating protein 1 (RanGAP1) has been implicated in various diseases, but its role in colorectal cancer (CRC) progression remains unclear. Using tumor tissues and public databases, we found that R...
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Article
Simulation of avascular tumor growth and drug response in a microfluidic device with a cellular automaton model
The microfluidic system is capable of recapitulating key attributes of in vivo circumstances and, therefore, becomes a valuable platform for better understanding tumor growth dynamics and evaluating drug effic...
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Article
Study on Precursor Distribution of a No-inner-wall Deposition Atmospheric Pressure Plasma Jet Used for Thin Film Deposition
An atmospheric pressure jet that effectively prevents inner wall deposition has been developed, and its precursor distribution and thin-film deposition characteristics have been studied. The laser scattering a...
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Article
Open AccessStrategies to increase the robustness of microbial cell factories
Engineering microbial cell factories have achieved much progress in producing fuels, natural products and bulk chemicals. However, in industrial fermentation, microbial cells often face various predictable and...
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Article
Open AccessAssessing peptic ulcer risk with the HAMPROW score in the general Chinese population
The timely identification of individuals at high risk for peptic ulcers (PUs) is vital in preventing gastrointestinal bleeding after antiplatelet therapy. This study was designed to determine PU risk factors a...
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Article
Numerical methods for the forward and backward problems of a time-space fractional diffusion equation
In this paper, we consider the numerical methods for both the forward and backward problems of a time-space fractional diffusion equation. For the two-dimensional forward problem, we propose a finite differenc...
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Article
Open AccessA promising target for breast cancer: B7-H3
Breast cancer (BC) is the second-leading factor of mortality for women globally and is brought on by a variety of genetic and environmental causes. The conventional treatments for this disease have limitations...
