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Article
Biomimetic design of highly flexible metal oxide nanofibrous membranes with exceptional mechanical performance for superior phosphopeptide enrichment
Develo** free-standing and mechanical robust membrane materials capable of superior enrichment of phosphopeptides for analyzing and identifying the specific phosphoproteome of cancer cells is significant in ...
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Article
Open AccessPrevalence of metabolic syndrome among patients with hepatocellular carcinoma of different etiologies: a retrospective study
This study compared the prevalences of metabolic syndrome and of cardiac or kidney comorbidities among patients with hepatocellular carcinoma (HCC) associated with metabolic dysfunction-related fatty liver dis...
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Article
Open AccessTranscranial alternating current stimulation improves quality of life in Parkinson’s disease: study protocol for a randomized, double-blind, controlled trial
The neural cells in the brains of patients with Parkinson’s disease (PWP) display aberrant synchronized oscillatory activity within the beta frequency range. Additionally, enhanced gamma oscillations may serve...
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Article
A machine learning approach to differentiate wide QRS tachycardia: distinguishing ventricular tachycardia from supraventricular tachycardia
Differential diagnosis of wide QRS tachycardia (WQCT) has been a challenging issue. Published algorithms to distinguish ventricular tachycardia (VT) and supraventricular tachycardia (SVT) have limited diagnost...
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Chapter and Conference Paper
Star Point Target Extraction with High Noise Background Based on Morphology
Star sensor positioning accuracy is the most important performance index of Star Sensor. However, noise is also an important factor affecting the positioning accuracy of star sensor. In order to extract the sm...
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Article
Semi-quantum ring signature protocol based on multi-particle GHZ state
The emergence of semi-quantum protocols reduces the conditions for the implementation of quantum signatures, so that users without quantum capabilities can communicate securely. As a kind of quantum signature,...
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Article
JMJD6 protects against isoproterenol-induced cardiac hypertrophy via inhibition of NF-κB activation by demethylating R149 of the p65 subunit
Histone modification plays an important role in pathological cardiac hypertrophy and heart failure. In this study we investigated the role of a histone arginine demethylase, Jumonji C domain-containing protein...
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Article
Asymmetric Circular Controlled Quantum State Transmission Scheme in Ideal and Noisy Environment
We present a four-participant scheme for the asymmetric circular controlled quantum states transmission. David is the controller, Alice, Bob and Charlie can complete the transmission of single-qubit, two-qubit...
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Article
Open AccessCorrection: CRISPR FISHer enables high-sensitivity imaging of nonrepetitive DNA in living cells through phase separation-mediated signal amplification
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Article
CircHIPK3 Regulates Vascular Smooth Muscle Cell Calcification Via the miR-106a-5p/MFN2 Axis
Atherosclerosis is the most common arterial disease and is closely related to vascular calcification. CircHIPK3 has been implicated in atherosclerosis development, but the possible downstream regulatory mechan...
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Article
GDH promotes isoprenaline-induced cardiac hypertrophy by activating mTOR signaling via elevation of α-ketoglutarate level
Numerous studies reveal that metabolism dysfunction contributes to the development of pathological cardiac hypertrophy. While the abnormal lipid and glucose utilization in cardiomyocytes responding to hypertro...
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Article
Open AccessCRISPR FISHer enables high-sensitivity imaging of nonrepetitive DNA in living cells through phase separation-mediated signal amplification
The dynamic three-dimensional structures of chromatin and extrachromosomal DNA molecules regulate fundamental cellular processes and beyond. However, the visualization of specific DNA sequences in live cells, ...
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Article
Quantum sealed-bid auction protocol based on quantum secret sharing
A quantum sealed-bid auction (QSA) with post-confirmation can realize the public verification of the honesty of bidders. In this paper, we apply the quantum secret sharing (QSS) into the post-confirmation. Sur...
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Article
Quantum Signature Scheme Based on Secret Sharing
Characterized by integrity and non-repudiation, digital signatures play an essential role in real life. Quantum digital signatures, which outperform classical types generally in safety, have been widely used i...
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Article
Quantum multi-proxy blind signature based on cluster state
Different from traditional digital signatures, quantum blind signatures can implement a signature without knowing the specific content, and their security is guaranteed by the basic principles of quantum mecha...
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Article
Tweety-Homolog 1 Facilitates Pain via Enhancement of Nociceptor Excitability and Spinal Synaptic Transmission
Tweety-homolog 1 (Ttyh1) is expressed in neural tissue and has been implicated in the generation of several brain diseases. However, its functional significance in pain processing is not understood. By disrupt...
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Article
Open AccessSpinal CCL2 Promotes Pain Sensitization by Rapid Enhancement of NMDA-Induced Currents Through the ERK-GluN2B Pathway in Mouse Lamina II Neurons
Previous studies have shown that CCL2 (C–C motif chemokine ligand 2) induces chronic pain, but the exact mechanisms are still unknown. Here, we established models to explore the potential mechanisms. Behaviora...
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Article
Learning to select pseudo labels: a semi-supervised method for named entity recognition
Deep learning models have achieved state-of-the-art performance in named entity recognition (NER); the good performance, however, relies heavily on substantial amounts of labeled data. In some specific areas s...
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Article
Open AccessThe sequence and de novo assembly of hog deer genome
Hog deer (Axis porcinus) is a small deer species in family Cervidae and has been undergoing a serious and global decline during the past decades. Chengdu Zoo currently holds a captive population of hog deer with ...
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Article
Open AccessA phase 1, open-label study of LCAR-B38M, a chimeric antigen receptor T cell therapy directed against B cell maturation antigen, in patients with relapsed or refractory multiple myeloma
Chimeric antigen receptor (CAR) T cell therapy has demonstrated proven efficacy in some hematologic cancers. We evaluated the safety and efficacy of LCAR-B38M, a dual epitope-binding CAR T cell therapy directe...
