1,897 Result(s)
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Zhen-**ang Zhao
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Article
Correction to: (+)-Catechin Alleviates CCI-Induced Neuropathic Pain in Rats by Modulating the IL34/CSFIR Axis and Attenuating the Schwann Cell-Macrophage Cascade Response in the DRG
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Article
(+)-Catechin Alleviates CCI-Induced Neuropathic Pain in Rats by Modulating the IL34/CSFIR Axis and Attenuating the Schwann Cell-Macrophage Cascade Response in the DRG
The aim of this study was to investigate the potential therapeutic applications of (+)-catechin in the treatment of neuropathic pain. In vivo study, 32 SD rats were randomly divided into four groups: sham grou...
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Article
Innovative coaxial high-temperature thin-film sensor with core–shell structure surpassing traditional multilayer films
High-temperature thin-film sensors (TFSs) often suffer from inadequate tolerance to elevated temperatures. In this study, an innovative approach is presented to fabricate in situ integrated TFSs with a core–sh...
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Article
Clinical characteristics of membranous nephropathy after allogeneic hematopoietic stem cell transplantation: A real-world multicenter study
Membranous nephropathy (MN) is a rare complication that can occur after allogeneic hematopoietic stem cell transplantation (allo-HSCT). MN patients may develop nephrotic syndrome or even kidney failure, which ...
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Article
Electrosynthesis of urea by using Fe2O3 nanoparticles encapsulated in a conductive metal–organic framework
The synthesis of urea by the electrochemical co-reduction of CO2 and nitrate is a crucial and challenging task. Catalysts typically suffer from either low Faradaic efficiency (FE) or inadequate current density, l...
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Open AccessSelf-powered triboelectric-responsive microneedles with controllable release of optogenetically engineered extracellular vesicles for intervertebral disc degeneration repair
Excessive exercise is an etiological factor of intervertebral disc degeneration (IVDD). Engineered extracellular vesicles (EVs) exhibit excellent therapeutic potential for disease-modifying treatments. Herein,...
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Open AccessAutomating psychological hypothesis generation with AI: when large language models meet causal graph
Leveraging the synergy between causal knowledge graphs and a large language model (LLM), our study introduces a groundbreaking approach for computational hypothesis generation in psychology. We analyzed 43,312...
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Article
The effect of Ti contents on energy storage properties of PLZST antiferroelectric ceramics
The effect of Ti contents on the microstructure, dielectric, and energy storage properties of prepared (Pb0.97La0.02) (Zr0.53Sn0.47)1-xTixO3 (PLZST) antiferroelectric ceramics by a traditional solid-state sinteri...
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Article
Successful treatment with efgartigimod as an add-on therapy in acute attack of anti-AQP4 antibody-positive NMOSD: a case report
Neuromyelitis Optica Spectrum Disorder (NMOSD) is an autoimmune demyelinating disease characterized by recurrent myelitis and optic neuritis. It is associated with high rates of relapse and disability. The mai...
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Open AccessReformulating lipid nanoparticles for organ-targeted mRNA accumulation and translation
Fully targeted mRNA therapeutics necessitate simultaneous organ-specific accumulation and effective translation. Despite some progress, delivery systems are still unable to fully achieve this. Here, we reformu...
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Open AccessNon-invasively identifying candidates of active surveillance for prostate cancer using magnetic resonance imaging radiomics
Active surveillance (AS) is the primary strategy for managing patients with low or favorable-intermediate risk prostate cancer (PCa). Identifying patients who may benefit from AS relies on unpleasant prostate ...
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Open AccessVisible and invisible factors affecting the job satisfaction of agency home caregivers in the UK
This qualitative study investigates the factors that affect the job satisfaction of home caregivers. It draws upon a thematic analysis of data from in-depth interviews with home caregivers in the UK and finds ...
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Article
Open AccessMETTL14 contributes to the progression of nasopharyngeal carcinoma through regulating the stability of AOC1 mRNA
Nasopharyngeal carcinoma (NPC) is a malignant epithelial tumor of the nasopharyngeal mucosa with a high incidence rate all over the world. Methyltransferase-like 14 (METTL14) is a major RNA N6-adenosine methyl...
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Article
Acetylcytidine modification of Amotl1 by N-acetyltransferase 10 contributes to cardiac fibrotic expansion in mice after myocardial infarction
Cardiac fibrosis is a pathological scarring process that impairs cardiac function. N-acetyltransferase 10 (Nat10) is recently identified as the key enzyme for the N4-acetylcytidine (ac4C) modification of mRNAs...
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Open AccessPerformance improvements in complementary metal oxide semiconductor devices and circuits based on fin field-effect transistors using 3-nm ferroelectric Hf0.5Zr0.5O2
In this work, a conventional HfO2 gate dielectric layer is replaced with a 3-nm ferroelectric (Fe) HZO layer in the gate stacks of advanced fin field-effect transistors (FinFETs). Fe-induced characteristics, e.g....
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Article
ROCK1 inhibition improves wound healing in diabetes via RIPK4/AMPK pathway
Refractory wounds are a severe complication of diabetes mellitus that often leads to amputation because of the lack of effective treatments and therapeutic targets. The pathogenesis of refractory wounds is com...
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Article
A DNA origami device spatially controls CD95 signalling to induce immune tolerance in rheumatoid arthritis
DNA origami is capable of spatially organizing molecules into sophisticated geometric patterns with nanometric precision. Here we describe a reconfigurable, two-dimensional DNA origami with geometrically patte...
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Article
Characterization of a pangolin SARS-CoV-2-related virus isolate that uses the human ACE2 receptor
Various SARS-CoV-2-related coronaviruses have been increasingly identified in pangolins, showing a potential threat to humans. Here we report the infectivity and pathogenicity of the SARS-CoV-2-related virus, ...
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Article
Biocatalytic desymmetrization for synthesis of chiral enones using flavoenzymes
Efficient methods for achieving desaturation of carbonyl compounds are highly sought after in organic chemistry. In contrast to synthetic approaches, enzymatic desaturation systems offer the potential to enhan...
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Article
Hole inhibition mechanisms of Mg/steel lap joint by pinless friction stir spot welding
Pinless friction stir spot welding (P-FSSW) was performed to manufacture Mg/steel lap joints. Orthogonal tests for P-FSSW of Mg/steel were investigated, and the main factors affecting the properties of Mg/stee...
