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5,977 Result(s)
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Article
Acetylcytidine modification of Amotl1 by N-acetyltransferase 10 contributes to cardiac fibrotic expansion in mice after myocardial infarction
Cardiac fibrosis is a pathological scarring process that impairs cardiac function. N-acetyltransferase 10 (Nat10) is recently identified as the key enzyme for the N4-acetylcytidine (ac4C) modification of mRNAs...
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Article
Study on the Arrangement of Roller Sets in the Transition Segment of the Pipe Belt Conveyor
The pipe belt conveyor is one of the most important bulk material transportation equipment in the world nowadays, which has great advantages compared with traditional belt conveyor and meets the requirements a...
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Article
Efficiency of PGK1 proteins delivered to the brain via a liposomal system through intranasal route administration for the treatment of spinocerebellar ataxia type 3
A patient-friendly and efficient treatment method for patients with spinocerebellar ataxia type 3 (SCA3) was provided through a nose-to-brain liposomal system. Initially, PGK1 was overexpressed in HEK 293-84Q-...
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Optimizing FeCoNiCrTi high-entropy alloy with hydrogen pum** effect to boost de/hydrogenation performance of magnesium hydride
The exploration of efficient, long-lived and cost-effective transition metal catalysts is highly desirable for the practical hydrogen storage of magnesium hydride (MgH2) in sustainable energy devices. Herein, FeC...
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Radiofrequency ablation for capsular-located versus noncapsular-located papillary thyroid microcarcinoma: a propensity score matching study of 1095 patients
To assess the safety and efficacy of radiofrequency ablation (RFA) for capsular-located papillary thyroid microcarcinoma (PTMC) in a large cohort and to compare its outcomes with those of noncapsular-located P...
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Article
Abnormal phosphorylation / dephosphorylation and Ca2+ dysfunction in heart failure
Heart failure (HF) can be caused by a variety of causes characterized by abnormal myocardial systole and diastole. Ca2+ current through the L-type calcium channel (LTCC) on the membrane is the initial trigger sig...
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Short- and long-term post-nephrectomy outcomes for retroperitoneal liposarcoma from a high-volume sarcoma center: a propensity score matching analysis
Multivisceral en bloc resection with the ipsilateral kidney is commonly performed in patients with retroperitoneal liposarcoma (RLPS). We evaluated the effect of nephrectomy on short- and long-term outcomes in...
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Design and analysis of a memristive Hopfield switching neural network and application to privacy protection
This paper considers the problem of making Hopfield neural networks (HNNs) generate multi-scroll chaotic attractors (MSCAs) and applying them to privacy protection. To this end, based on HNNs and memristors, a...
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Article
Entropy based optimal scale selection and attribute reduction in multi-scale interval-set decision tables
One of the current research gaps in multi-scale data analysis is studying information systems characterized by attributes with interval sets as attribute values and multiple scales. To address this gap, we fir...
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Article
Myocardial Transit Time Map** by CMR: A Novel Indicator of Microcirculatory Dysfunction in Cardiac Amyloidosis
Cardiac amyloidosis (CA) is characterized by the deposition of amyloid fibrils within the myocardium, resulting in a restrictive physiology. Although microvascular dysfunction is a common feature, it is diffic...
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Article
Towards integrated textile display systems
We receive approximately 80% of our external environmental information through vision, making display technology an essential component of modern life. The evolution of device structures has led to the iterati...
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Article
Open AccessA broad neutralizing nanobody against SARS-CoV-2 engineered from an approved drug
SARS-CoV-2 infection is initiated by Spike glycoprotein binding to the human angiotensin-converting enzyme 2 (ACE2) receptor via its receptor binding domain. Blocking this interaction has been proven to be an ...
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miR-338-5p regulated the NF-κB/MAPK pathway to alleviate inflammation and oxidative stress by targeting IL-6 in rats with atrial fibrillation
The aim of this study was to investigate the functional effect of miR-338-5p targeting IL-6 on NF-κB/MAPK pathway-mediated inflammation and oxidative stress in atrial fibrillation (AF) rats. AF model rats were...
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Article
Open AccessSubsurface A-site vacancy activates lattice oxygen in perovskite ferrites for methane anaerobic oxidation to syngas
Tuning the oxygen activity in perovskite oxides (ABO3) is promising to surmount the trade-off between activity and selectivity in redox reactions. However, this remains challenging due to the limited understandin...
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Article
Nonlinear dynamics of fault electromechanical coupling transmission system in electrical vehicles
To analyze the vibration characteristics of the electromechanical coupling transmission system of electrical vehicles under gear faults, an electromechanical coupling transmission system including two-stage me...
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Article
SG-NeRF: Sparse-Input Generalized Neural Radiance Fields for Novel View Synthesis
Traditional neural radiance fields for rendering novel views require intensive input images and pre-scene optimization, which limits their practical applications. We propose a generalization method to infer sc...
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Open AccessIdentification of lipid metabolism-related gene signature in the bone marrow microenvironment of multiple myelomas through deep analysis of transcriptomic data
Dysregulated lipid metabolism in the bone marrow microenvironment (BMM) plays a vital role in multiple myeloma (MM) development, progression, and drug resistance. However, the exact mechanism by which lipid me...
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Ensemble successor representations for task generalization in offline-to-online reinforcement learning
In reinforcement learning (RL), training a policy from scratch with online experiences can be inefficient because of the difficulties in exploration. Recently, offline RL provides a promising solution by givin...
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Article
Perfectionism and suicidal ideation: the serial mediating roles of appearance-based rejection sensitivity and loneliness
Guided by the perfectionism social disconnection model (PSDM), this study focused on understanding the perfectionism-suicidality link by including appearance-based rejection sensitivity and loneliness as media...
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Study on Parallel Bond and Smooth Joint Dual Model Parameter Calibration of Mechanical Properties of Shale Under Pressure
Employing a rational numerical model to characterize the compressive mechanical properties of shale is highly significant for large-scale shale-related engineering demonstrations. By analyzing the effects of t...