-
Article
Open AccessNon-rigid point cloud registration for middle ear diagnostics with endoscopic optical coherence tomography
Middle ear infection is the most prevalent inflammatory disease, especially among the pediatric population. Current diagnostic methods are subjective and depend on visual cues from an otoscope, which is limite...
-
Article
Open AccessStability bearing capacity of concrete filled steel tubular columns subjected to long-term load
Concrete-filled steel tube (CFST) are commonly used in modern building and bridge applications. Despite their popularity, studies on the investigation of the influence of long-term load on the stability bearin...
-
Article
Open AccessImproved Plasmonic Hot-Electron Capture in Au Nanoparticle/Polymeric Carbon Nitride by Pt Single Atoms for Broad-Spectrum Photocatalytic H2 Evolution
A hybrid co-catalysts system comprising Au nanoparticles (NPs) and PtSAs with different functions was constructed on the polymeric carbon nitride (PCN) surface by double-solven...
-
Article
Open AccessIsolated Fe-Co heteronuclear diatomic sites as efficient bifunctional catalysts for high-performance lithium-sulfur batteries
The slow redox kinetics of polysulfides and the difficulties in decomposition of Li2S during the charge and discharge processes are two serious obstacles to the practical application of lithium-sulfur batteries. ...
-
Article
Open AccessUnmasking the biological function and regulatory mechanism of NOC2L: a novel inhibitor of histone acetyltransferase
NOC2 like nucleolar associated transcriptional repressor (NOC2L) was recently identified as a novel inhibitor of histone acetyltransferase (INHAT). NOC2L is found to have two INHAT function domains and regulat...
-
Article
An innovative and convenient technique to reduce anastomotic leakage after double stapling anastomosis: laparoscopic demucositized suture the overlap** point of the “dog ear” area
Anastomotic leakage (AL) is a major cause of postoperative morbidity and mortality in the treatment of colorectal cancer. The aim of this study was to investigate an innovative and convenient technique of lapa...
-
Article
Influencing factors for the decline of limb muscle strength and the association with all-cause mortality: evidence from a nationwide population-based cohort study
The decline of muscle strength, a typical characteristic of sarcopenia, greatly affects aging-related health outcomes; however, prospective data on influencing factors and mortality in the Chinese population a...
-
Article
Experimental and DFT-D3 study of sensitivity and sensing mechanism of ZnSnO3 nanosheets to C3H6O gas
To find a new type of sensing material with high sensitivity to acetone gas, in this paper, a first-principles method based on density functional theory was used to study the gas-sensing mechanism of perovskit...
-
Chapter and Conference Paper
Shape Matters: Deformable Patch Attack
Though deep neural networks (DNNs) have demonstrated excellent performance in computer vision, they are susceptible and vulnerable to carefully crafted adversarial examples which can mislead DNNs to incorrect ...
-
Article
Open AccessConstipation induced gut microbiota dysbiosis exacerbates experimental autoimmune encephalomyelitis in C57BL/6 mice
Constipation is a common gastrointestinal dysfunction which has a potential impact on people's immune state and their quality of life. Here we investigated the effects of constipation on experimental autoimmun...
-
Article
Open AccessGinkgolic acid and anacardic acid are specific covalent inhibitors of SARS-CoV-2 cysteine proteases
In the urgent campaign to develop therapeutics against SARS-CoV-2, natural products have been an important source of new lead compounds.
-
Article
Open AccessFecal microbiota transplantation from patients with autoimmune encephalitis modulates Th17 response and relevant behaviors in mice
The significance of the microbiota-gut-brain axis has been increasingly recognized as a major modulator of autoimmunity. Here, we aim to characterize the gut microbiota of a large cohort of treatment-naïve anti-N
-
Chapter and Conference Paper
Experimental Study on Creep of Concrete Filled Steel Tube Under Eccentric Compression
Several concrete-filled steel tube (CFT) arch bridges have been built over the past few years around the world. Current design codes do not address the design of CFT arch bridges, particularly with considerat...
-
Article
A simple self-regulating permeability and selectivity of poly (arylene ether ketone) with amino groups for gas separation membrane
Poly (arylene ether ketone) containing different content of the amino groups (Am-PAEK) polymer membranes were prepared by nucleophilic polycondensation used as gas separation membranes. Am-PAEK was synthesized...
-
Article
Poly(arylene ether ketone) containing amino and fluorenyl groups for highly selective of gas separation
In this study, a series of poly(arylene ether ketone) containing amino and fluorenyl groups (Am-PAFEK-X) were successfully prepared by the polycondensation, which was confirmed by analizing its chemical struct...
-
Article
Traditional Chinese Medicine in Multiple Sclerosis: Theory and Practice
Multiple sclerosis (MS) is a disease with complex etiology and pathophysiology. Approved drugs for MS treatment are only partly effective, and some of them show obvious side effects and resistance. In this rev...
-
Article
Open AccessAerobic condition enhances bacteriostatic effects of silver nanoparticles in aquatic environment: an antimicrobial study on Pseudomonas aeruginosa
The intensive applications of silver nanoparticles (AgNPs) inevitably cause continuous release of such materials into environments, as a consequence posing potential risks to microbial communities in engineere...
-
Article
Open AccessCystatin C as a potential therapeutic mediator against Parkinson’s disease via VEGF-induced angiogenesis and enhanced neuronal autophagy in neurovascular units
Cystatin C (CYS C, Cst3) is an endogenous cysteine protease inhibitor that plays neuroprotective roles in neurodegenerative diseases. We aimed to explore the association of CYS C with Parkinson’s disease (PD) mod...
-
Chapter and Conference Paper
Research on Interactive Prototype Design and Experience Method Based on Open Source
This paper argues that, from the perspective of interactive prototy** and experience, the hardware technology based on open source and thinking, can promote further development of interaction design research...
-
Article
Open AccessNur77 exacerbates PC12 cellular injury in vitro by aggravating mitochondrial impairment and endoplasmic reticulum stress
The nuclear orphan receptor, Nur77 plays important roles in neuroimflammation, apoptosis, and dopaminergic neurodegeneration. We conducted a further mechanistic investigation into the association of Nur77 with...
