90 Result(s)
within
Zhao **-Shan
Chemistry
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Article
A novel dual-signal output strategy for POCT of CEA based on a smartphone electrochemical aptasensing platform
A smartphone-based electrochemical aptasensing platform was developed for the point-of-care testing (POCT) of carcinoembryonic antigen (CEA) based on the ferrocene (Fc) and PdPt@PCN-224 dual-signal labeled st...
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Article
Two-color emissive AIEgens with anti-Kasha property for dual-organelle imaging and phototherapy
Despite the rapid development of probes for targeting single organelle, the construction of robust dual-organelle targeting probes with multicolor emission was rarely reported. Herein, two dual-emissive aggreg...
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Open AccessHydralazine loaded nanodroplets combined with ultrasound-targeted microbubble destruction to induce pyroptosis for tumor treatment
Pyroptosis, a novel type of programmed cell death (PCD), which provides a feasible therapeutic option for the treatment of tumors. However, due to the hypermethylation of the promoter, the critical protein Gas...
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Recent advances in chemical protein synthesis: method developments and biological applications
The central dogma of modern biology underscores the pivotal roles proteins play in diverse biological processes, the study of which necessitates advanced methods to produce proteins with precision and versatil...
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The Interplay Between Epilepsy and Parkinson’s Disease: Gene Expression Profiling and Functional Analysis
The results of many epidemiological studies suggest a bidirectional causality may exist between epilepsy and Parkinson’s disease (PD). However, the underlying molecular landscape linking these two diseases rem...
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Recent Progress in Fabrication and Structural Design of Thermal Conductive Polymer Composites
In recent years, the demand direction for electronic equipment has expanded into embedded and miniaturized devices. The heat radiation problem has become one of the most significant factors for hindering the d...
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Research on accelerating the corrosion of 7B04 aluminium alloy in the Lacticaseibacillus paracasei environment
Microbially influenced corrosion is one of the main issues of concern in industries due to its significant economic impact. In this work, we focused on Lacticaseibacillus paracasei, a typical microorganism identi...
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Open AccessTargeted delivery of organic small-molecule photothermal materials with engineered extracellular vesicles for imaging-guided tumor photothermal therapy
Imaging-guided photothermal therapy (PTT) for cancers recently gathered increasing focus thanks to its precise diagnosis and potent therapeutic effectiveness. Croconaine (CR) dyes demonstrate potential in expa...
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A novel monospecific tetravalent IgG1-(scFv)2 version shown enhanced neutralizing and Fc-mediated effector functions against SARS-CoV-2
Neutralizing monoclonal antibodies (nMABs) have been proved to be effective therapeutics in treating coronavirus disease (COVID-19). To enhance the potency of nMAB 553–15, we generated a novel monospecific tet...
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Article
Open AccessCAFs targeted ultrasound-responsive nanodroplets loaded V9302 and GLULsiRNA to inhibit melanoma growth via glutamine metabolic reprogramming and tumor microenvironment remodeling
Despite rapid advances in metabolic therapies over the past decade, their efficacy in melanoma has been modest, largely due to the interaction between cancer-associated fibroblasts (CAFs) and cancer cells to p...
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Article
Synthesis, characterization of CdII-based complexes for efficient detection of copper(II) ions and antibiotics
In this work, two compounds, namely [Cd2(HL)(4,4′-bpy)(H2O)]n (1), [Cd2(HL)(bpa)(H2O)·2H2O]n (2) (2,3-bis(3,5-dicarboxylphenxoy)benzoic acid (H5L), 4,4′-bipyridine (4,4'-bpy) and 1,2-bi(4-pyridyl)ethane (bpa)), h...
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Cytochalasins from the Endophytic Fungus Fusarium sp. GDGJ-366
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Copper-catalysed convergent regio- and enantioselective alkynylallylic substitution
Asymmetric allylic and propargylic substitutions have seen numerous applications in synthetic chemistry, constructing stereogenic centres vicinal to unsaturated C–C bonds. However, the merger of these two subs...
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Article
The improvement effect of surfactants on hydrogenation at condition containing water for Cu/SiO2 catalysts
In the industrial production, water exists inevitably into feed stocks in the form of impurity, and it can produce a negative effect in the hydrogenation reaction due to the preferential adsorption of water on...
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Article
Knitted structural design of MXene/Cu2O based strain sensor for smart wear
Electronic textiles present an enticing prospect for personal health assessment and physical monitoring, owing to their strong stretchability, high flexibility, mechanical robustness and high capacity in sensi...
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Thermal and mechanical properties of poly(latic acid) reinforced with silanized basalt scales
Biodegradable poly(lactic acid) (PLA)-based composites were prepared using PLA and basalt scale (BS) via a solution-blending method. BS surfaces were treated using a silane coupling agent, and their surface pr...
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Open AccessOral vaccination with recombinant Lactobacillus casei expressing Aha1 fused with CTB as an adjuvant against Aeromonas veronii in common carp (Cyprinus carpio)
Aeromonas veronii (A. veronii) is a pathogenic that can infect human, animal and aquatic organisms, in which poses a huge threat to the health of many aquatic organisms such as Cyprinus carpio. In this study, Lac...
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Reconfiguring perovskite interface via R4NBr addition reaction toward efficient and stable FAPbI3-based solar cells
Defect states in perovskite films restrict the interfacial stability and open-circuit voltage of perovskite solar cells. Here, aiming at superior interfacial passivation, we investigate the reconfiguration of ...
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Article
Fiber Bending Flexibility Evaluation by Worm-like Chain Model
A new method for characterizing fiber bending flexibility was developed by worm-like chain model proposed by Kratky-Porod,[1] which was first introduced to the pulp and paper field in this study. For the three ty...
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Article
Computational study reveals substituted benzimidazole derivatives’ binding selectivity to PI3Kδ and PI3Kγ
Phosphatidylinositol 3-kinase (PI3K) is a key regulatory kinase in the PI3K/AKT/mTOR signaling pathway, which is involved in the regulation of cell proliferation, differentiation, apoptosis, and angiogenesis. ...
