193 Result(s)
-
Article
Preclinical study and first-in-human imaging of [18F]FAP-2286, and comparison with 2-[18F]FDG PET/CT in various cancer patients
Fibroblast-activated protein (FAP) is highly expressed in cancer-associated fibroblasts (CAFs) of many solid cancers, but low or absent in normal tissues. Our study aimed to develop a novel FAP-specific tracer...
-
Article
Open AccessPhenotypic and genetic analysis of children with unexplained neurodevelopmental delay and neurodevelopmental comorbidities in a Chinese cohort using trio-based whole-exome sequencing
Trio-based whole-exome sequencing (trio-WES) enables identification of pathogenic variants, including copy-number variants (CNVs), in children with unexplained neurodevelopmental delay (NDD) and neurodevelopme...
-
Article
Pigmented villonodular synovitis detected by [68Ga]Ga-FAPI-04 PET/CT
-
Article
Clinical study of electroacupuncture improving sleep electroencephalogram and event-related potential in patients with somatoform disorders
To observe the effects of electroacupuncture (EA) on sleep electroencephalogram (EEG) and event-related potential (ERP) in patients with somatoform disorders (SFD).
-
Article
Open AccessAssessment of water enema PET/CT: an effective imaging technique for the diagnosis of incidental colorectal 18F-FDG uptake
To validate the feasibility of water enema PET/CT (WE-PET/CT) in incidental colorectal 18F-FDG uptake and improve the accuracy of diagnosing colorectal neoplastic lesions.
-
Article
Open AccessSARS-CoV-2 N protein enhances the anti-apoptotic activity of MCL-1 to promote viral replication
Viral infection in respiratory tract usually leads to cell death, impairing respiratory function to cause severe disease. However, the diversity of clinical manifestations of SARS-CoV-2 infection increases the...
-
Article
[68Ga]Ga-FAPI-04 PET/CT on assessing Crohn’s disease intestinal lesions
Fibrosis and inflammation are major pathological changes of Crohn’s disease (CD). Early detection and accurate severity evaluation of CD are critical for patient’s prognosis. Endoscopy is widely used to evalua...
-
Article
Mediastinum-type lung cancer on 68Ga-FAPI PET/CT with cardiac insufficiency as the first symptom
-
Article
The Superiority of 68 Ga-FAPI-04 over 18F-FDG in a Case of Gallbladder Cancer
A 56-year-old man presented with vague upper abdominal pain for more than 4 months. His abdominal ultrasound and MRI showed thickening of the neck and base of the gallbladder and nodule formation at the base o...
-
Article
Retraction Note: Patients with ankylosing spondylitis treatment by golimumab: a systematic review and meta‑analysis
-
Article
Propionic Acid-Based PET Imaging of Prostate Cancer
This study aimed to evaluate the potential value of 2-[18F]fluoropropionic acid ([18F]FPA) for PET imaging of prostate cancer (PCa) and to explore the relationship between [18F]FPA accumulation and fatty acid syn...
-
Article
RETRACTED ARTICLE: Osteotomy in lateral position for correcting severe thoracolumbar kyphosis combined with hip flexion contracture in ankylosing spondylitis: a case report and literature review
-
Article
Open AccessDiagnostic performance of ultrasonography, dual-phase 99mTc-MIBI scintigraphy, early and delayed 99mTc-MIBI SPECT/CT in preoperative parathyroid gland localization in secondary hyperparathyroidism
Secondary hyperparathyroidism (SHPT) usually requires parathyroidectomy when drug regimens fail. However, obtaining an exact preoperative map of the locations of the parathyroid glands is a challenge. The purp...
-
Article
RETRACTED ARTICLE: Patients with ankylosing spondylitis treatment by golimumab: a systematic review and meta-analysis
The goal of this study was to review relevant randomized controlled trials in order to determine the clinical efficacy of golimumab in the treatment of ankylosing spondylitis (AS).
-
Article
Targeting Phosphatidylethanolamine with Fluorine-18 Labeled Small Molecule Probe for Apoptosis Imaging
Externalization of phosphatidylethanolamine (PE) in dying cells makes the phospholipid an attractive target for apoptosis imaging. However, no ideal PE-targeted positron emission tomography (PET) radiotracer w...
-
Article
Validation of R-2-[18F]Fluoropropionic Acid as a Potential Tracer for PET Imaging of Liver Cancer
2-[18F]Fluoropropionic acid (RS-[18F]FPA) has shown potential value as a short-chain fatty acid positron emission tomography (PET) tracer for the detection of liver cancer. However, RS-[18F]FPA is a mixture of 2-
-
Article
Apoptotic PET Imaging of Rat Pulmonary Fibrosis with Small-Molecule Radiotracer
The purpose of this study was to assess the potential utility of small-molecule apoptotic radiotracer, 2-(5-[18F]fluoropentyl)-2-methyl malonic acid ([18F]ML-10), for positron emission tomography (PET)/computed t...
-
Article
Open AccessElevated tumor-to-liver uptake ratio (TLR) from 18F–FDG-PET/CT predicts poor prognosis in stage IIA colorectal cancer following curative resection
The prognostic value of the tumor-to-liver uptake ratio (TLR) from 18-fluoro-2-deoxyglucose positron emission tomography/computed tomography (18F–FDG-PET/CT) in the early stage of colorectal cancer (CRC) is uncle...
-
Article
Open AccessEndocrine complications in patients with thalassaemia major
-
Article
Downregulation of miR-383 promotes glioma cell invasion by targeting insulin-like growth factor 1 receptor
Invasiveness is a major clinical feature of glioma, an aggressive brain tumor with poor prognosis. Although there is emerging evidence that some microRNAs are involved in the glioma cell invasion process, it r...
