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Article
Open AccessThe association of SOD and HsCRP with the efficacy of sulforaphane in schizophrenia patients with residual negative symptoms
Emerging evidence indicates a connection between oxidative stress, immune-inflammatory processes, and the negative symptoms of schizophrenia. In addition to possessing potent antioxidant and anti-inflammatory ...
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Article
Open AccessHigh circulating MIF levels indicate the association with atypical antipsychotic-induced adverse metabolic effects
Atypical antipsychotics (AAPs) are primary medications for schizophrenia (SZ). However, their use is frequently associated with the development of adverse metabolic effects, and the mechanisms behind these neg...
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Article
Open AccessAssociation of cytokines levels, psychopathology and cognition among CR-TRS patients with metabolic syndrome
Clozapine-resistant treatment-refractory schizophrenia (CR-TRS) patients face significant clinical challenges. While links between metabolic syndrome (MetS) and inflammatory cytokines in schizophrenia have bee...
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Article
Open AccessSmoking affects symptom improvement in schizophrenia: a prospective longitudinal study of male patients with first-episode schizophrenia
Patients with schizophrenia (SCZ) smoke up to three times more than general people. However, there are conflicting results regarding the relationship between tobacco smoke and clinical symptom severity in SCZ....
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Article
Open AccessThe neutrophil-to-Lymphocyte ratio is associated with clinical symptoms in first-episode medication-naïve patients with schizophrenia
Innate immunity has been shown to be associated with schizophrenia (Sch). This study explored the relationship between symptoms and neutrophil-to-lymphocyte ratio (NLR) (a marker of innate immunity) in patient...
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Article
Open AccessEfficacy of standard operating procedures for fall protection in hospitalized patients with schizophrenia
Fall-related injury is the most common cause of functional disability and mortality in the older population. Falls in patients with schizophrenia are one of the major concerns in psychiatric hospitals. This st...
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Article
Open AccessSex-based influential factors for dental caries in patients with schizophrenia
Schizophrenia is a common mental disorder that seriously affects patients’ daily lives and brings heavy psychological and economic burdens to their families and society. The oral problems of patients with schi...
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Open AccessDance/movement therapy for improving balance ability and bone mineral density in long-term patients with schizophrenia: a randomized controlled trial
Fractures are common accidents for long-term hospitalized patients with schizophrenia (SZ) in psychiatric hospitals, and once they occur, patients usually endure the pain of fractures for a long time. Accumula...
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Article
Open AccessDynamic functional thalamocortical dysconnectivity in schizophrenia correlates to antipsychotics response
Although many studies have showed abnormal thalamocortical networks in patients with schizophrenia (SCZ), the dynamic functional thalamocortical connectivity of individuals with SCZ and the effect of antipsych...
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Article
Sex differences in the association between suicidal ideation and neurocognitive function in Chinese patients with schizophrenia
There is increasing evidence that sex differences exist in many clinical manifestations of patients with schizophrenia, including suicidal ideation (SI) and neurocognitive function. The present study was perfo...
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Article
Open AccessThe percentage and clinical correlates of alexithymia in stable patients with schizophrenia
Alexithymia is a common, but less-recognized affective deficit in patients with schizophrenia. To date, no definitive conclusions have been drawn about the relationship between alexithymia and the clinical sym...
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Article
Ketamine induces rapid antidepressant effects via the autophagy-NLRP3 inflammasome pathway
Sub-anesthetic ketamine has rapid-onset effects for the treatment of major depressive disorder (MDD). However, the mechanism underlying ketamine’s antidepressant properties remains unclear. Recent studies have...
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Article
High On-Treatment Platelet Reactivity as Predictor of Long-term Clinical Outcomes in Stroke Patients with Antiplatelet Agents
The purpose was to explore the value of high on-treatment platelet reactivity (HTPR) in predicting long-term clinical outcomes for stroke patients. The platelet reactivity was assayed after being treated with ...
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Open AccessCorrection: The association of clinical correlates, metabolic parameters, and thyroid hormones with suicide attempts in first-episode and drug-naïve patients with major depressive disorder comorbid with anxiety: a large-scale cross-sectional study
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The prevalence and clinical correlates of metabolic syndrome and cardiometabolic alterations in 430 drug-naive patients in their first episode of schizophrenia
Although metabolic abnormalities and metabolic syndrome (MetS) have been extensively investigated in schizophrenia, few studies have examined them in first-episode drug-naive (FEDN) patients.
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Article
Open AccessSex difference in the interrelationship between TNF-α and oxidative stress status in first-episode drug-naïve schizophrenia
Increasing evidence indicates that dysregulated TNF-α and oxidative stress (OxS) contribute to the pathophysiology of schizophrenia. Additionally, previous evidence has demonstrated sex differences in many asp...
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Article
Correction to: Major Depressive Disorder: Advances in Neuroscience Research and Translational Applications
A correction to this paper has been published: https://doi.org/10.1007/s12264-021-00694-9
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Article
Disturbances of affective cognition in mood disorders
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Open AccessMajor Depressive Disorder: Advances in Neuroscience Research and Translational Applications
Major depressive disorder (MDD), also referred to as depression, is one of the most common psychiatric disorders with a high economic burden. The etiology of depression is still not clear, but it is generally ...
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Article
Open AccessThe association of clinical correlates, metabolic parameters, and thyroid hormones with suicide attempts in first-episode and drug-naïve patients with major depressive disorder comorbid with anxiety: a large-scale cross-sectional study
The associated factors of suicide attempts in patients with major depressive disorder (MDD) comorbid with anxiety remains unclear. To the best of our knowledge, this is the first study with a large sample size...