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    Article

    The high level food-grade expression of glutamate decarboxylase in Bacillus subtilis through combination of genomic integration and free plasmid

    γ-Aminobutyric acid (GABA) is a bioactive compound with diverse physiological functions. It has a wide range of applications in food and medicine and mainly biosynthesized through glutamate decarboxylase (GAD)...

    Huihui Lv, **nrui Yu, Tongle Liu, **g Wu in Systems Microbiology and Biomanufacturing (2024)

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    High On-Treatment Platelet Reactivity as Predictor of Long-term Clinical Outcomes in Stroke Patients with Antiplatelet Agents

    The purpose was to explore the value of high on-treatment platelet reactivity (HTPR) in predicting long-term clinical outcomes for stroke patients. The platelet reactivity was assayed after being treated with ...

    Huihui Lv, Zidong Yang, Haibo Wu, Mingyuan Liu in Translational Stroke Research (2022)

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    Enhancement of FK520 production in Streptomyces hygroscopicus by combining traditional mutagenesis with metabolic engineering

    FK520 (ascomycin), a 23-membered macrolide with immunosuppressive activity, is produced by Streptomyces hygroscopicus. The problem of low yield and high impurities (mainly FK523) limits the industrialized product...

    Zhituo Yu, Huihui Lv, Yuanjie Wu, Tengyun Wei in Applied Microbiology and Biotechnology (2019)