28 Result(s)

Article

MiR-653-5p drives osteoarthritis pathogenesis by modulating chondrocyte senescence

Due to the unclear pathogenesis of osteoarthritis (OA), effective treatment for this ailment is presently unavailable. Accumulating evidence points to chondrocyte senescence as a key driver in OA development. ...

Yucheng Lin, Lu Zhang, Mingliang Ji, Sinuo Shen, Yuzhi Chen… in Arthritis Research & Therapy (2024)

Article

CDCA5 promoted cell invasion and migration by activating TGF-β1 pathway in human ovarian cancer cells

The gene cell division cycle associated 5 (CDCA5), also called sororin, has oncogenic characteristics and is upregulated in various carcinomas. Nevertheless, the involvement of CDCA5 in ovarian cancer (OC), a ...

Qingsong Zhang, Rong Zhang, Yuzhi Li, **aojun Yang in Journal of Ovarian Research (2024)

Article

Efficacy and safety of anticoagulant for treatment and prophylaxis of VTE patients with renal insufficiency: a systemic review and meta-analysis

Patients with venous thromboembolism (VTE) comorbid renal insufficiency (RI) are at higher risk of bleeding and thrombosis. Recommendations in guidelines on anticoagulation therapy for those patients remain am...

Shuangshuang Ma, Guohui Fan, Feiya Xu, **aomeng Zhang, Yinong Chen… in Thrombosis Journal (2024)

Article

Association of preoperative frailty with the risk of postoperative delirium in older patients undergoing hip fracture surgery: a prospective cohort study

This study aimed to explore the correlation between preoperative frailty and the risk of postoperative delirium (POD) in older patients undergoing hip fracture surgery.

Chunyu Feng, Haotian Wu, Ziheng Qi, Yuzhi Wei… in Aging Clinical and Experimental Research (2024)

Article

Structural transition of parenthood among Chinese nulliparous couples with planned pregnancies, 2013–2019

The postponement of parenthood is a global public health issue that has received attention of many public health experts. However, few studies have investigated the postponement in marriage age, marriage and c...

Long Wang, Chunying Han, **nyi Lv, Shuai Zeng, Rongwei Mu, Yuzhi Deng… in BMC Public Health (2023)

Article

Complications and hospitalization costs in patients with hypothyroidism following total hip arthroplasty

Hypothyroidism is a common disease in the US population. The impact of hypothyroidism on perioperative complications of total hip arthroplasty is poorly understood. To examine risk factors and hospitalization ...

Yuanyuan Huang, Yuzhi Huang, Yuhang Chen… in Journal of Orthopaedic Surgery and Research (2023)

Article

Descriptions of sham acupuncture in randomised controlled trials: a critical review of the literature

Sham acupuncture is usually used to assess the specific effects of acupuncture. However, the reporting quality of sham acupuncture remains unclear despite its critical importance in understanding and analyzing...

Yixuan **e, **aoyu Liu, Tinglan Liu, Chiyun Sun… in BMC Complementary Medicine and Therapies (2023)

Article

FBXW7β loss-of-function enhances FASN-mediated lipogenesis and promotes colorectal cancer growth

Continuous de novo fatty acid synthesis is required for the biosynthetic demands of tumor. FBXW7 is a highly mutated gene in CRC, but its biological functions in cancer are not fully characterized. Here, we re...

Wenxia Wei, Baifu Qin, Weijie Wen, Boyu Zhang… in Signal Transduction and Targeted Therapy (2023)

Article

A cross-sectional study on knowledge and behavior regarding medication usage among guardians of left-behind children: evidence from China

The primary objective of this study was to evaluate knowledge and behavior of medication use among guardians of left-behind children (LBC) and non-left-behind children (NLBC).

Qiaoyue Ge, Yao Zhou, Zeyuan Sun, **a Jiang, Lu Zhang, Chunsong Yang… in BMC Public Health (2023)

Article

Efficacy and safety of intranasal midazolam versus intranasal ketamine as sedative premedication in pediatric patients: a meta-analysis of randomized controlled trials

Intranasal midazolam and ketamine have been widely used as sedative premedication in children. It is difficult to determine which one yields better sedative effects for clinical practice. We conducted the pres...

Bingchen Lang, Huiqing Wang, Yuzhi Fu, Linan Zeng, Liang Huang… in BMC Anesthesiology (2022)

Article

Comparison of malignancy and spatial distribution between latent and clinical prostate cancer: an 8-year biopsy study

Current prostate cancer (PCa) screening may detect nonprogressive lesion, leading to overdiagnosis and overtreatment. The purpose of the present study is to investigate whether the tumor pathological origin of...

Liang Zhen, Zhou Zhien, Huang Hanzi, Wu **ngcheng… in European Journal of Medical Research (2022)

Article

Correction to: Bariatric Surgery Does Not Improve Semen Quality: Evidence from a Meta-analysis

Zhiguang Gao, Yuzhi Liang, Sen Yang, Tao Zhang, Zuyuan Gong, Min Li… in Obesity Surgery (2022)

Article

Paternal smoking and preterm birth: a population-based retrospective cohort study among non-smoking women aged 20–49 years in rural China

To comprehensively evaluate the association of paternal smoking and preterm birth (PTB).

Long Wang, Yuzhi Deng, Ying Yang, Fangchao Liu, Qin Xu, Zuoqi Peng… in Reproductive Health (2022)

Article

Association of parental prepregnancy BMI with neonatal outcomes and birth defect in fresh embryo transfer cycles: a retrospective cohort study

Parental body mass index (BMI) is associated with pregnancy outcomes. But the effect of parental prepregnancy BMI on offspring conceived via in vitro fertilization (IVF) or intracytoplasmic sperm injection (IC...

Ruixue Chen, Lifen Chen, Yifeng Liu, Feixia Wang… in BMC Pregnancy and Childbirth (2021)

Article

Regulatory B cells improve ventricular remodeling after myocardial infarction by modulating monocyte migration

Overactivated inflammatory responses contribute to adverse ventricular remodeling after myocardial infarction (MI). Regulatory B cells (Bregs) are a newly discovered subset of B cells with immunomodulatory rol...

Jiao Jiao, Shujie He, Yiqiu Wang, Yuzhi Lu, Muyang Gu… in Basic Research in Cardiology (2021)

Article

Neoadjuvant chemoradiotherapy improves survival in locally advanced adenocarcinoma of esophagogastric junction compared with neoadjuvant chemotherapy: a propensity score matching analysis

To analyze whether neoadjuvant chemoradiotherapy (nCRT) could improve the survival for patients with adenocarcinoma of the esophagogastric junction compared with neoadjuvant chemotherapy (nCT). Both neoadjuvan...

**g Li, Qun Zhao, Xueke Ge, Yuzhi Song, Yuan Tian, Shuoshuo Wang, Ming Liu… in BMC Surgery (2021)

Article

Multiple inferior vena cava aneurysms mimic a retroperitoneal tumor: a case report

Inferior vena cava (IVC) aneurysms are extremely rare with variable clinical manifestations. Patients are usually asymptomatic or present with complications of thrombosis and rupture. To date, there have been ...

Yuzhi Zuo, Zhenyu Zhang, Bingbing Shi, Zhigang Ji, Zhongming Huang in BMC Urology (2020)

Article

Spectrum of activity of dasatinib against mutant KIT kinases associated with drug-sensitive and drug-resistant gastrointestinal stromal tumors

The majority of GISTs express mutationally activated KIT. Imatinib and sunitinib are approved KIT-inhibiting therapies. Their efficacy is usually hampered by the acquired multiple secondary drug-resistance KIT mu...

Chunling Zeng, Li Zhu, **aona Jia, Yuzhi Pang, Zhang Li, **ao**g Lu… in Gastric Cancer (2020)

Article

Change in the cause of inpatient mortality after arthroplasty: a retrospective study

Although arthroplasty has been proved to be a safe and effective procedure, data regarding inpatient mortality rates associated with arthroplasty in China is unclear. We aimed to investigate the inpatient mort...

Yuzhi Zuo, ** Lin, ** **, Wenwei Qian… in Journal of Orthopaedic Surgery and Research (2019)

Article

Atypical GATA transcription factor TRPS1 represses gene expression by recruiting CHD4/NuRD(MTA2) and suppresses cell migration and invasion by repressing TP63 expression

Transcriptional repressor GATA binding 1 (TRPS1), an atypical GATA transcription factor, functions as a transcriptional repressor and is also implicated in human cancers. However, the underlying mechanism of T...

Yuzhi Wang, Xue Lin, Xue Gong, Lele Wu, Jun Zhang, Weiguang Liu, Jian Li… in Oncogenesis (2018)