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Open AccessWhen DNA-damage responses meet innate and adaptive immunity
When cells proliferate, stress on DNA replication or exposure to endogenous or external insults frequently results in DNA damage. DNA-Damage Response (DDR) networks are complex signaling pathways used by multi...
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Article
An amorphous FeMoO4 nanorod array enabled high-efficiency oxygen evolution electrocatalysis in alkaline seawater
The development of highly efficient and durable oxygen evolution reaction (OER) catalysts for seawater electrolysis is of great importance for applications. Here, an amorphous FeMoO4 nanorod array on Ni foam is r...
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Open AccessGut microbiota-dependent phenylacetylglutamine in cardiovascular disease: current knowledge and new insights
Phenylacetylglutamine (PAGln) is an amino acid derivate that comes from the amino acid phenylalanine. There are increasing studies showing that the level of PAGln is associated with the risk of different cardi...
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Article
Log-periodic power law hybrid model based on BP neural network
Stock market crashes bring about huge economic loss, so predicting the stock market crashes is extremely important for both the investors and practitioners. Back propagation (BP) neural network performed great...
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Open AccessAssociation between testosterone and cancers risk in women: a two-sample Mendelian randomization study
Previous observational studies have explored the correlation between testosterone and cancer risk. However, the causal association between testosterone and various cancer types in women remains inconclusive. T...
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Article
Multimodal Feature Association-based Stereo Visual SLAM Method
Much work has been done to improve visual SLAM systems by integrating point, line, and plane features into the bundle adjustment model, however little attention has been paid to explore the associations betwee...
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Article
Identification and Experimental Validation of Parkinson’s Disease with Major Depressive Disorder Common Genes
Parkinson’s disease (PD) is the second most common neurodegenerative disease that affects about 10 million people worldwide. Non-motor and motor symptoms usually accompany PD. Major depressive disorder (MDD) i...
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Open AccessLiver injury in children: signal analysis of suspected drugs based on the food and drug administration adverse event reporting system
Evidence of drug-induced liver injury is abundant in adults but is lacking in children. Our aim was to identify suspected drug signals associated with pediatric liver injury.
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Open AccessUsing disproportionality analysis to explore the association between periostitis and triazole antifungals in the FDA Adverse Event Reporting System Database
Though triazole antifungals are the first choice for preventing and treating invasive fungal infections, periostitis caused by voriconazole has been described in emerging case reports; however, no studies exis...
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Open AccessEfficacy and safety of intranasal midazolam versus intranasal ketamine as sedative premedication in pediatric patients: a meta-analysis of randomized controlled trials
Intranasal midazolam and ketamine have been widely used as sedative premedication in children. It is difficult to determine which one yields better sedative effects for clinical practice. We conducted the pres...
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Open AccessRetraction Note to: RIPK3 interactions with MLKL and CaMKII mediate oligodendrocytes death in the develo** brain
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Open AccessCL-ACP: a parallel combination of CNN and LSTM anticancer peptide recognition model
Anticancer peptides are defence substances with innate immune functions that can selectively act on cancer cells without harming normal cells and many studies have been conducted to identify anticancer peptide...
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Article
Apelin-36 Protects HT22 Cells Against Oxygen-Glucose Deprivation/Reperfusion-Induced Oxidative Stress and Mitochondrial Dysfunction by Promoting SIRT1-Mediated PINK1/Parkin-Dependent Mitophagy
Oxidative stress and mitochondrial dysfunction are involved in cerebral ischemia/reperfusion injury-induced neuronal apoptosis. Mitophagy is the main method to eliminate dysfunctional mitochondria. Apelin-36, ...
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Open AccessEndoscopically controlled surgery with open hemilaminectomy for the treatment of intradural extramedullary tumors: an operative technique and short-term outcomes of 20 consecutive cases
To present a surgical technique for the treatment of intradural extramedullary (IDEM) tumors by using endoscopically controlled surgery with open hemilaminectomy technique.
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miR-550a-3/NFIC plays a driving role in esophageal squamous cell cancer cells proliferation and metastasis partly through EMT process
In this study, the functional role of miR-550a-3 and its direct target nuclear factor IC (NFIC) in esophageal squamous cell cancer (ESCC) cells were explored. Differential expression of miR-550a-3 in ESCC tiss...
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Article
Susceptibility of Helicoverpa armigera to two Bt toxins, Cry1Ac and Cry2Ab, in northwestern China: toward develo** an IRM strategy
Extensive unofficial planting of Bt cotton expressing Cry1Ac toxin has occured for the past two decades in northwestern China, and no mandatory refuge policy has been adopted. The status of Cry1Ac susceptibili...
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Article
Climate change favours a destructive agricultural pest in temperate regions: late spring cold matters
Global climate change has profound consequences on survival and reproduction of arthropods. In particular, in temperate regions changes in spring temperatures have a major impact on crop pest population dynami...
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Open AccessRETRACTED ARTICLE: RIPK3 interactions with MLKL and CaMKII mediate oligodendrocytes death in the develo** brain
Oligodendrocyte progenitor cells (OPCs) death is a key contributor to cerebral white matter injury (WMI) in the develo** brain. A previous study by our group indicated that receptor-interacting proteins (RIP...
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Open AccessGlobal metabolomics reveals potential urinary biomarkers of esophageal squamous cell carcinoma for diagnosis and staging
We performed a metabolomics study using liquid chromatography-mass spectrometry (LC-MS) combined with multivariate data analysis (MVDA) to discriminate global urine profiles in urine samples from esophageal sq...
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Neonatal mortality in the urban and rural China between 1996 and 2013: a retrospective study
One of the proposed United Nations post-2015 sustainable development goals is to eliminate avoidable neonatal deaths by 2030. This study aims to examine changes in neonatal mortality rate (NMR) and cause-speci...