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    Article

    The pathogenetic significance of exhausted T cells in a mouse model of mature B cell neoplasms

    Dysfunctional anti-tumor immunity has been implicated in the pathogenesis of mature B cell neoplasms, such as multiple myeloma and B cell lymphoma; however, the impact of exhausted T cells on disease developme...

    Asuka Shibamiya, Yurie Miyamoto-Nagai, Shuhei Koide in Cancer Immunology, Immunotherapy (2023)

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    Article

    Genetic and transcriptional landscape of plasma cells in POEMS syndrome

    POEMS syndrome is a rare paraneoplastic disease associated with monoclonal plasma cells; however, the pathogenic importance of plasma cells remains unclear. We performed comprehensive genetic analyses of plasm...

    Yuhei Nagao, Naoya Mimura, June Takeda, Kenichi Yoshida, Yusuke Shiozawa in Leukemia (2019)

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    Open Access

    Cyclosporine is a potential curative treatment option for advanced thymoma

    Thymectomy can effectively cure most thymoma patients; however, patients with advanced thymoma typically require chemotherapy, which is associated with limited efficacy in this context. Here we provide the fir...

    Yusuke Isshiki, Hiroaki Tanaka, Yoshio Suzuki in Experimental Hematology & Oncology (2017)