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Article
Open AccessDynamic radiomics based on contrast-enhanced MRI for predicting microvascular invasion in hepatocellular carcinoma
To exploit the improved prediction performance based on dynamic contrast-enhanced (DCE) MRI by using dynamic radiomics for microvascular invasion (MVI) in hepatocellular carcinoma (HCC).
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Article
Open AccessDevelopment and testing of a polygenic risk score for breast cancer aggressiveness
Aggressive breast cancers portend a poor prognosis, but current polygenic risk scores (PRSs) for breast cancer do not reliably predict aggressive cancers. Aggressiveness can be effectively recapitulated using ...
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Article
Development and external validation of a multiparametric MRI-based radiomics model for preoperative prediction of microsatellite instability status in rectal cancer: a retrospective multicenter study
To establish and validate a radiomics model based on multiparametric magnetic resonance imaging (MRI), and to predict microsatellite instability (MSI) status in rectal cancer patients.
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Article
Open AccessTransfer efficiency and impact on disease phenotype of differing methods of gut microbiota transfer
To test causal relationships between complex gut microbiota (GM) and host outcomes, researchers frequently transfer GM between donor and recipient mice via embryo transfer (ET) rederivation, cross-fostering (C...
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Article
Open AccessAutomatic Measurement of Silicon Lattice Spacings in High-Resolution Transmission Electron Microscopy Images Through 2D Discrete Fourier Transform and Inverse Discrete Fourier Transform
Line width (i.e., critical dimension, CD) is a crucial parameter in integrated circuits. To accurately control the CD in manufacturing, a reasonable CD measurement algorithm is required. We develop an automati...
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Article
Open AccessPerformance determinants of unsupervised clustering methods for microbiome data
In microbiome data analysis, unsupervised clustering is often used to identify naturally occurring clusters, which can then be assessed for associations with characteristics of interest. In this work, we syste...
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Article
Open AccessNodal immune flare mimics nodal disease progression following neoadjuvant immune checkpoint inhibitors in non-small cell lung cancer
Radiographic imaging is the standard approach for evaluating the disease involvement of lymph nodes in patients with operable NSCLC although the impact of neoadjuvant immune checkpoint inhibitors (ICIs) on lym...
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Article
Open AccessProgPerm: Progressive permutation for a dynamic representation of the robustness of microbiome discoveries
Identification of features is a critical task in microbiome studies that is complicated by the fact that microbial data are high dimensional and heterogeneous. Masked by the complexity of the data, the problem...
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Article
A dependent Dirichlet process model for survival data with competing risks
In this paper, we first propose a dependent Dirichlet process (DDP) model using a mixture of Weibull models with each mixture component resembling a Cox model for survival data. We then build a Dirichlet proce...
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Article
Precise measurement of particle size in colloid system based on the development of multiple-angle dynamic light scattering apparatus
Dynamic light scattering (DLS) is a widely used, non-invasive and in-situ method for particle size measurement. However, the precision of the measurement results is still under discussion. Theoretically, the a...
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Article
Aberrant interhemispheric functional connectivity in first-episode, drug-naïve major depressive disorder
Many studies have indicated that depression is associated with impairment of the topological organization of the brain functional network, which may lead to disruption of mood and cognition in depressive patie...
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Article
Fractures in a nationwide population-based cohort of users of breast cancer hormonal therapy
Although users of aromatase inhibitors have higher total fracture risk in some randomized trials, little is known about their risk outside of clinical trials or in older higher-risk cohorts.
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Article
Active coherent control of nanoscale light confinement: Modulation of plasmonic modes and position of hotspots for surface-enhanced Raman scattering detection
Multistep plasmonic nanostructures can induce the deep modulation of electromagnetic-field interactions on the nanoscale for positioning hotspots, and this generation of enhanced fields is important in many op...
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Article
Photoelectrochemical determination of Hg(II) via dual signal amplification involving SPR enhancement and a folding-based DNA probe
The authors describe a highly sensitive and selective photoelectrochemical (PEC) assay for mercury(II) ions. It is based on a dual signal amplification strategy. The first enhancement results from the surface ...
