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Article
Open AccessRAISING is a high-performance method for identifying random transgene integration sites
Both natural viral infections and therapeutic interventions using viral vectors pose significant risks of malignant transformation. Monitoring for clonal expansion of infected cells is important for detecting ...
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Article
Open AccessCloning-free CRISPR/Cas system facilitates functional cassette knock-in in mice
Although the CRISPR/Cas system has enabled one-step generation of knockout mice, low success rates of cassette knock-in limit its application range. Here we show that cloning-free, direct nuclear delivery of C...
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Article
Open AccessDevelopment of detection method for novel fusion gene using GeneChip exon array
Fusion genes have been recognized to play key roles in oncogenesis. Though, many techniques have been developed for genome-wide analysis of fusion genes, a more efficient method is desired.