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Article
Open AccessSalvage surgery for pouch-related complication after ileal pouch–anal anastomosis: a report of two cases
Pouch-related complications (PRCs), such as pelvic abscesses and perianal complex fistulas, can occur after ileal pouch–anal anastomosis (IPAA) in ulcerative colitis (UC). They are often difficult to treat and...
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Article
Open AccessResection of anorectal fistula cancer associated with Crohn’s disease after preoperative chemoradiotherapy: a case report
Anorectal fistula cancer is often diagnosed in an advanced state, and radical resection is difficult when invasion of the pelvic wall is observed. In addition, there is currently no clear evidence for perioper...
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Article
A case of fulminant amoebic colitis during systemic chemotherapy for gastric cancer
Amoebiasis is a parasitic infection caused by the protozoan, Entamoeba histolytica. At times, amoebiasis is activated under immunosuppressive conditions such as chemotherapy. We report a case of fulminant amoe...
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Article
Open AccessTesticular metastasis 9 years after resection of primary descending colon cancer with simultaneous pulmonary metastasis: a case report
Metastatic testicular cancer is rare. In particular, primary colorectal cancer rarely metastasizes to the testes. This study reports a case of testicular metastasis recurrence 9 years after the resection of a ...
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Article
Open AccessCancer-specific tissue-resident memory T-cells express ZNF683 in colorectal cancer
Tissue-resident memory T (Trm) cells are associated with cytotoxicity not only in viral infection and autoimmune disease pathologies but also in many cancers. Tumour-infiltrating CD103+ Trm cells predominantly co...
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Article
Open AccessTumor-infiltrating T cells as a risk factor for lymph node metastasis in patients with submucosal colorectal cancer
Approximately 10% of patients with colorectal cancer with submucosal invasion have lymph node metastasis. Pathological risk factors for lymph node metastasis have varying sensitivities and specificities. To pr...
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Article
Open AccessLocally advanced rectal cancer receiving total neoadjuvant therapy combined with nivolumab: a case report and literature review
The standard treatment for locally advanced rectal cancer (LARC) is preoperative chemoradiotherapy (CRT) followed by surgery and adjuvant chemotherapy. However, it has been suggested that intensification of ne...
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Article
Predicting lateral pelvic lymph node metastasis based on magnetic resonance imaging before and after neoadjuvant chemotherapy for patients with locally advanced lower rectal cancer
We examined the association between pathological lateral pelvic lymph node (LPLN) metastasis and the LPLN diameter in patients with locally advanced rectal cancer (LARC) who received a neoadjuvant chemotherapy...
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Article
Open AccessSome Gammaproteobacteria are enriched within CD14+ macrophages from intestinal lamina propria of Crohn’s disease patients versus mucus
Crohn’s disease causes chronic inflammation in the gastrointestinal tract and its pathogenesis remains unclear. In the intestine of Crohn’s disease patients, CD14+CD11+CD163low macrophages contribute to inflammat...
