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Article
Nutritional Supplements and Periodontal Disease Prevention—Current Understanding
This review updates the current knowledge on nutrient supplements, which are reported as effective in maintaining the health of periodontal tissues or preventing diseases, as a complementary therapy to existin...
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Article
The ion channel TRPV1 regulates the activation and proinflammatory properties of CD4+ T cells
The membrane channel TRPV1 is well studied as a pain receptor, but its function beyond sensory neurons remains unclear. Raz and colleagues demonstrate that TRPV1 is also a non–store-operated calcium channel on...
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Article
The Role of Distinct T Cell Subsets in Periodontitis—Studies from Humans and Rodent Models
Periodontal disease results from an interaction between the host’s defense mechanisms and the microorganisms that constitute the dental plaque biofilm, and penetrate gingival tissue. Therefore, the progression...
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Article
Open AccessEffect of Porphyromonas gingivalis infection on post-transcriptional regulation of the low-density lipoprotein receptor in mice
Periodontal disease is suggested to increase the risk of atherothrombotic disease by inducing dyslipidemia. Recently, we demonstrated that proprotein convertase subtilisin/kexin type 9 (PCSK9), which is known ...