258 Result(s)
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Yuhui **n
Life Sciences
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Article
The Relationship Between Heavy Metals and Missed Abortion: Using Mediation of Serum Hormones
Accumulating evidence suggests that heavy metal exposure may have adverse effects on the fetal development. Furthermore, disruption of serum hormone homeostasis can result in the adverse pregnancy outcomes. Th...
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Open AccessIntegrating apaQTL and eQTL analysis identifies a potential causal variant associated with lung adenocarcinoma risk in the Chinese population
Alternative polyadenylation (APA) plays a crucial role in cancer biology. Here, we used data from the 3′aQTL-atlas, GTEx, and the China Nan**g Lung Cancer GWAS database to explore the association between apaQ...
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Open AccessA dual RNA-seq analyses revealed dynamic arms race during the invasion of walnut by Colletotrichum gloeosporioides
Walnut anthracnose caused by Colletotrichum gloeosporioides seriously endangers the yield and quality of walnut, and has now become a catastrophic disease in the walnut industry. Therefore, understanding both pat...
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Open AccessEvaluation of vaccine candidates against Rhodococcus equi in BALB/c mice infection model: cellular and humoral immune responses
Rhodococcus equi (R. equi) is a zoonotic opportunistic pathogen that mainly causes fatal lung and extrapulmonary abscesses in foals and immunocompromised individuals. To date, no commercial vaccine against R. equ...
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The LasmiR858-MYB111 module enhances the antioxidant capacity of green leaf lettuce by promoting flavonoid biosynthesis
Flavonoids are secondary metabolites found in plants that possess antioxidant properties. MicroRNAs are small non-coding RNAs that play a crucial role in regulating gene expression and are involved in both dev...
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Article
Open AccessGLUT1 promotes cell proliferation via binds and stabilizes phosphorylated EGFR in lung adenocarcinoma
While previous studies have primarily focused on Glucose transporter type 1 (GLUT1) related glucose metabolism signaling, we aim to discover if GLUT1 promotes tumor progression through a non-metabolic pathway.
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RNAi screens identify HES4 as a regulator of redox balance supporting pyrimidine synthesis and tumor growth
NADH/NAD+ redox balance is pivotal for cellular metabolism. Systematic identification of NAD(H) redox regulators, although currently lacking, would help uncover unknown effectors critically implicated in the coor...
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Effects of the invasive red swamp crayfish (Procambarus clarkii) on eelgrass-dominated clearwater lakes: the role of bioturbation
The invasive red swamp crayfish Procambarus clarkii (Girard, 1852) can affect freshwater ecosystems, their macrophyte communities in various ways. To examine the effects of red swamp crayfish on clearwater macrop...
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Elucidation of genes enhancing natural product biosynthesis through co-evolution analysis
Streptomyces has the largest repertoire of natural product biosynthetic gene clusters (BGCs), yet develo** a universal engineering strategy for each Streptomyces species is challenging. Given that some Streptom...
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Article
Effects of Exogenous 2,4-Dichlorophenoxyacetic Acid, Glutathione, and L-Buthionine Sulfoximine on Intracellular Redox State and Hormone Levels and Their Links with Proliferation in Picea pungens Somatic Embryogenesis
Cellular redox state and hormone levels have important regulatory roles in the process of somatic embryogenesis (SE), but experimental data on the topic are limited in conifer SE. This study investigated chang...
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Open AccessANKFY1 bridges ATG2A-mediated lipid transfer from endosomes to phagophores
Macroautophagy is a process that cells engulf cytosolic materials by autophagosomes and deliver them to lysosomes for degradation. The biogenesis of autophagosomes requires ATG2 as a lipid transfer protein to ...
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Article
QTL map** and candidate gene analysis reveal two major loci regulating green leaf color in non-heading Chinese cabbage
Two major-effect QTL GlcA07.1 and GlcA09.1 for green leaf color were fine mapped into 170.25 kb and 191.41 kb intervals on chromosomes A07 and A09, respectively, and were validated by transcriptome analysis.
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Open AccessIdentification of the GAox gene family in potato (Solanum tuberosum L.) and its expression analysis in response to drought stress
GAox is a key enzyme involved in GA biosynthesis pathway and plays an important role in regulating various processes in plant life cycle. However, it has not been systematic, studies have been conducted in pot...
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Article
A Multi-objective Apple Leaf Disease Detection Algorithm Based on Improved TPH-YOLOV5
To address the challenge of apple leaf disease target recognition in complex environments, we proposed an improved apple leaf disease detection algorithm based on TPH-YOLOV5. We filtered, supplemented, and enh...
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Article
Set7/9 aggravates ischemic brain injury via enhancing glutamine metabolism in a blocking Sirt5 manner
The aberrant expression of methyltransferase Set7/9 plays a role in various diseases. However, the contribution of Set7/9 in ischemic stroke remains unclear. Here, we show ischemic injury results in a rapid el...
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A Profile of Drug-Resistant Mutations in Mycobacterium tuberculosis Isolates from Guangdong Province, China
Guangdong Province, China’s largest economy, has a high incidence of tuberculosis (TB). At present, there are few reports on the distribution, transmission and drug resistance of Mycobacterium tuberculosis (Mtb) ...
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Article
IL-33 aggravates extranodal NK/T cell lymphoma aggressiveness and angiogenesis by activating the Wnt/β-catenin signaling pathway
Extranodal NK/T cell lymphoma (ENKTCL) is an extremely aggressive form of lymphoma and lacks of specific diagnostic markers. The study intended to unearth the role of interleukin-33 (IL-33) in ENKTCL. RT-qPCR ...
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Designing future peanut: the power of genomics-assisted breeding
Integrating GAB methods with high-throughput phenoty**, genome editing, and speed breeding hold great potential in designing future smart peanut cultivars to meet market and food supply demands.
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Identification of geographical origin and adulteration of Northeast China soybeans by mid-infrared spectroscopy and spectra augmentation
Mathematical models based on infrared spectroscopy and machine learning have been successfully used to trace the origin of soybeans. However, as previous research reported, it is necessary to employ spectra da...
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Levels of nutrient enrichment determine the emergence of zooplankton from resting egg banks
We studied the effects of varying levels of nitrogen (N), phosphorus (P), and nitrogen and phosphorus mixture (NP) enrichment on the hatching of resting eggs to determine whether nutrient enrichment levels aff...
