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Article
Open AccessTemporal turnover of viral biodiversity and functional potential in intertidal wetlands
As the central members of the microbiome networks, viruses regulate the composition of microbial communities and drive the nutrient cycles of ecosystems by lysing host cells. Therefore, uncovering the dynamic ...
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Article
RA-UNet: an improved network model for image denoising
Due to the rapid advancement of GPU computing, deep learning has lately been widely used in image denoising. Most deep learning methods require noise-free images as labels, which are often difficult or impossi...
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Article
Open AccessFacile Semiconductor p–n Homojunction Nanowires with Strategic p-Type Do** Engineering Combined with Surface Reconstruction for Biosensing Applications
A novel photoelectrochemical (PEC) photosensor composed of GaN nanowire-on-Si platform demonstrates record-high responsivity of 247.8 mA W−1 with ultra-stable operation charact...
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Article
QTL for plant structure type and their influence on seed-related traits in wheat
Plant structure type (PT) is an important complex and quantitative trait to regulating yield potential and stress tolerance in wheat (Triticum aestivum L.). In this study, a recombinant inbred line (RIL) populati...
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Article
Open AccessInfluence of subcutaneous adipose tissue index on prognosis in cirrhotic patients following endoscopic therapy: a retrospective cohort study
The relation of adipose tissue depletion with prognostic outcome of variceal bleeding among cirrhotic patients is still inconclusive. The present work explored whether adipose tissue, which was measured based ...
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Article
Esophagogastroscopic Abnormalities Potentially Guided Patients Younger than 50 Years Old to Undergo Colonoscopy Earlier: A Retrospective Cross-Sectional Study
The incidence of early-onset colorectal cancer (CRC) is continuously increasing worldwide. Current guidelines in China recommend average-risk individuals starting CRC screening at age 50.
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Article
Effect of aspirin, warfarin, and proton-pump inhibitors on performance of fecal immunochemical test in colorectal cancer screening: a systematic review and meta-analysis
This study aims to investigate the impact of antithrombotic agents and proton-pump inhibitors (PPIs) on fecal immunochemical test (FIT). PubMed, EMBASE, Web of Science, Cochrane Central, and Google Scholar wer...
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Article
Open AccessThe clinical characteristics of focal acute pancreatitis based on imaging diagnosis: comparison with non-localized acute pancreatitis- a preliminary result
Focal acute pancreatitis is a special type of acute pancreatitis, which diagnosis is based on image showing a focal mass formation in the pancreas. For acute pancreatitis with or without focal inflammatory enl...
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Article
Open AccessIdentification of a cholesterol metabolism-related prognostic signature for multiple myeloma
Multiple myeloma (MM) is a prevalent hematological malignancy that poses significant challenges for treatment. Dysregulated cholesterol metabolism has been linked to tumorigenesis, disease progression, and the...
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Article
Open AccessFirstborn children’s sex specific emotions and behaviors during mothers’ second pregnancy after implementation of the universal two-child policy in China
The present cross-sectional study aimed to identify sex-specific characteristics and other factors for firstborn children’s emotions and behaviors during their mothers’ second pregnancy after the implementatio...
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Article
Open AccessA multi-omics study to investigate the progression of the Correa pathway in gastric mucosa in the context of cirrhosis
Patients with liver cirrhosis (LC) are prone to gastric mucosa damage. We investigated the alterations of gastric mucosa in LC patients and their possible mechanisms through multi-omics.
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Article
Papillary fibroblast-recruiting injectable self-healing multifunctional hydrogels for wound regeneration
The recruitment of key cells to regeneration sites is a promising strategy to promote functional wound healing. Dermal fibroblasts exhibit a heterogeneous population of cells during homeostasis and in response...
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Article
Open AccessEffects of four disease-controlling agents (chlorothalonil, CuCl2, harpin, and melatonin) on postharvest jujube fruit quality
Postharvest senescence and disease development can reduce the nutritional value of fresh jujube fruit. Herein, four different disease-controlling agents (chlorothalonil, CuCl2, harpin and melatonin) were separate...
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Article
Open AccessRecombinant measles virus vaccine rMV-Hu191 exerts an oncolytic effect on esophageal squamous cell carcinoma via caspase-3/GSDME-mediated pyroptosis
Oncolytic viruses have recently been proven to be an effective and promising cancer therapeutic strategy, but there is rare data about oncolytic therapy in esophageal squamous cell carcinoma (ESCC), especially...
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Article
Open AccessA new generation Mpro inhibitor with potent activity against SARS-CoV-2 Omicron variants
Emerging SARS-CoV-2 variants, particularly the Omicron variant and its sublineages, continually threaten the global public health. Small molecule antivirals are an effective treatment strategy to fight against...
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Article
Towards green economy: Environmental performance of belt and road initiative in China
As a Chinese solution to build a community of human destiny, Belt and Road Initiative (BRI) has shown China’s international responsibility by promoting its green development. Based on the annual panel data of ...
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Article
Do pilot free trade zones improve the green total factor productivity? Evidence from a quasi-natural experiment in China
China’s pilot free trade zone (PFTZ) is an important national strategy to achieve high-quality development, so it is necessary to discuss the effect of PFTZ implementation on green total factor productivity (G...
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Article
Constructing the separation pathway for photo-generated carriers by diatomic sites decorated on MIL-53-NH2(Al) for enhanced photocatalytic performance
High yield production of phenol from hydroxylation of benzene with low energy consumption is of paramount importance, but still challenging. Herein, a new strategy, consisting of using diatomic synergistic mod...
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Article
Pharmacological Activation of GPR55 Improved Cognitive Impairment Induced by Lipopolysaccharide in Mice
Our previous research found that activation of GPR55 can alleviate cognitive impairment induced by amyloid-beta 1–42 (Aβ1-42) and streptozotocin in mice, but the role of GPR55 in the pathogenesis of cognitive imp...
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Article
Open AccessGenome-wide identification and expression analysis reveals spinach brassinosteroid-signaling kinase (BSK) gene family functions in temperature stress response
Brassinosteroid (BR)- signaling kinase (BSK) is a critical family of receptor-like cytoplasmic kinase for BR signal transduction, which plays important roles in plant development, immunity, and abiotic stress ...
