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Article
Improving Granulosa Cell Function in Premature Ovarian Failure with Umbilical Cord Mesenchymal Stromal Cell Exosome-Derived hsa_circ_0002021
The therapeutic potential of exosomes from human umbilical cord mesenchymal stem cells (HUMSCs-Exo) for delivering specific circular RNAs (circRNAs) in treating premature ovarian failure (POF) is not well unde...
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Article
High-performance ultrathin Ag electrodes by chemical bond anchoring Ag atoms for stretchable organic light-emitting devices
The progress of stretchable organic light-emitting devices (OLEDs) has brought about new possibilities for highly functional wearable electronics. However, the efficiency and durability of stretchable OLEDs ha...
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Article
Open AccessSmall animal PET imaging with the 68Ga-labeled pH (low) insertion peptide-like peptide YJL-4 in a triple-negative breast cancer mouse model
The aim of this study was to prepare a novel 68Ga-labeled pH (low) insertion peptide (pHLIP)-like peptide, YJL-4, and determine its value for the early diagnosis of triple-negative breast cancer (TNBC) via in viv...
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Article
Open AccessMalaria epidemiological characteristics and control in Guangzhou, China, 1950–2022
Malaria was once widespread in Guangzhou, China. However, a series of control measures have succeeded in eliminating local malaria infections. Based on the analysis of the characteristics of malaria epidemics ...
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Article
Photochemical diversification of strong C(sp3)–H bonds enabled by allyl bromide and sodium fluoride
The development of practical approaches for the selective functionalization of strong, neutral C(sp3)–H bonds, such as those in petroleum-derived hydrocarbons, is of general interest but remains a remarkable chal...
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Article
Synthesis and Evaluation of Radioiodine-Labeled pH (Low) Insertion Peptide Variant 7-Like Peptide as a Noninvasive Tumor Microenvironment Imaging Agent in a Mouse MDA-MB-231 Triple-Negative Breast Cancer Model
The pH (low) insertion peptide (pHLIP) family can target the tumor microenvironment (TME). If pHLIP can be labeled with radioiodine, the imaging and treatment of tumors can be considered. However, tyrosine and...
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Article
Polypyrrole Hollow Nanotubes Loaded with Au and Fe3O4 Nanoparticles for Simultaneous Determination of Ascorbic Acid, Dopamine, and Uric Acid
An ultrasensitive electrochemical biosensor was fabricated for electroanalytical determination of ascorbic acid(AA), dopamine(DA) and uric acid(UA) individually and simultaneously based on polypyrrole hollow n...
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Article
Open AccessSpatiotemporal regulation of endogenous MSCs using a functional injectable hydrogel system for cartilage regeneration
Hydrogels have been extensively favored as drug and cell carriers for the repair of knee cartilage defects. Recruiting mesenchymal stem cells (MSCs) in situ to the defect region could reduce the risk of contam...
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Article
Knockdown of TRIM22 Relieves Oxygen–Glucose Deprivation/Reoxygenation-Induced Apoptosis and Inflammation Through Inhibition of NF-κB/NLRP3 Axis
Tripartite motif-containing 22 (TRIM22) has been documented to participate in numerous cellular activities during human diseases. However, whether TRIM22 is involved in the regulation of neuronal survival duri...
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Article
Copper stress-induced changes in biomass accumulation, antioxidant activity and flavonoid contents in Belamcanda chinensis calli
Here, the effects of copper stress (CS) on biomass accumulation, physiological parameters of oxidative stress and flavonoid production were investigated in Belamcanda chinensis calli. They were subjected to coppe...
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Article
Open AccesspHLIP(Var7)-P1AP suppresses tumor cell proliferation in MDA-MB-231 triple-negative breast cancer by targeting protease activated receptor 1
Protease-activated receptor 1 (PAR1) is a signaling protein ubiquitously present on the surface of tumor cells, and its homologous protein fragment, PAR1-activating peptide (P1AP), can inhibit protein signal t...
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Article
Open AccessMaternally inherited coronary heart disease is associated with a novel mitochondrial tRNA mutation
Coronary heart disease (CHD) is the most common cause of mortality globally, yet mitochondrial genetic mutations associated with CHD development remain incompletely understood.
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Article
PKM2 Involved in Neuronal Apoptosis on Hypoxic-ischemic Encephalopathy in Neonatal Rats
Pyruvate Kinase isozymes M2 (PKM2) is a glycolytic enzyme involved in glycolysis that decarboxylates phosphoenolpyruvate to pyruvate and generates ATP. PKM2 also plays a significant role in tumor growth, in ce...
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Article
Open AccessUsing low-risk factors to generate non-integrated human induced pluripotent stem cells from urine-derived cells
Because the lack of an induced pluripotent stem cell (iPSC) induction system with optimal safety and efficiency limits the application of these cells, development of such a system is important.
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Article
Open AccessFluorodeoxyglucose-positron emission tomography/computed tomography imaging features of colloid adenocarcinoma of the lung: a case report
Colloid adenocarcinoma of the lung is a rare subtype of variants of invasive adenocarcinomas. We report the appearance of this unusual entity on 18F-fluorodeoxyglucose positron emission tomography/computed tomogr...
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Chapter and Conference Paper
Identification of an Antifungal Bacillus Strain and Studies on Its Antifungal Active Ingredients
Strain NK-2 which has broad spectrum of antifungal activity against eight kinds of phytopathogenic fungi was identified as Bacillus amyloliquefaciens by analysis of partial 16S rDNA, gyrA gene, and rpoB gene sequ...
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Article
Nutrients and oxygen alter reservoir biochemical characters and enhance oil recovery during biostimulation
Biostimulation of petroleum reservoir to improve oil recovery has been conducted in a large number of oilfields. However, the roles and linkages of organic nutrients, inorganic salts and oxygen content during ...
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Article
Improving synchronous ability between complex networks
We investigate the synchronization ability between complex networks and propose a near optimal connection strategy based on one connection. Numerical simulations on scale-free, small-world and random network a...
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Article
Vibration characteristics and power transmission of coupled rectangular plates with elastic coupling edge and boundary restraints
Coupled-plate structures are widely used in the practical engineering such as aeronautical, civil and naval engineering etc. Limited works can be found on the vibration of the coupled-plate structure due to th...
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Article
Modeling dynamics of disaster spreading in community networks
In this paper, we investigate the dynamics of disaster spreading in community networks. Unlike the case in other kinds of complex networks, the transitions between the self-healing and spreading dynamics for c...
