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Article
Open AccessSimultaneous targeted and discovery-driven clinical proteoty** using hybrid-PRM/DIA
Clinical samples are irreplaceable, and their transformation into searchable and reusable digital biobanks is critical for conducting statistically empowered retrospective and integrative research studies. Cur...
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Article
Open AccessUltra-fast label-free quantification and comprehensive proteome coverage with narrow-window data-independent acquisition
Mass spectrometry (MS)-based proteomics aims to characterize comprehensive proteomes in a fast and reproducible manner. Here we present the narrow-window data-independent acquisition (nDIA) strategy consisting...
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Article
Open AccessHybrid-DIA: intelligent data acquisition integrates targeted and discovery proteomics to analyze phospho-signaling in single spheroids
Achieving sufficient coverage of regulatory phosphorylation sites by mass spectrometry (MS)-based phosphoproteomics for signaling pathway reconstitution is challenging, especially when analyzing tiny sample am...
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Article
Open AccessDietary resistant starch ameliorating lipopolysaccharide-induced inflammation in meat ducks associated with the alteration in gut microbiome and glucagon-like peptide 1 signaling
Consumption of resistant starch (RS) has been associated with various intestinal and systemic health benefits, but knowledge of its effects on intestinal health and inflammatory response in stressed birds is l...
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Article
Precise regulation of acid pretreatment for red mud SCR catalyst: Targeting on optimizing the acidity and reducibility
Red mud (RM), as an alkaline waste, was recently proved to be a promising substitute for the SCR catalyst. Dealkalization could improve the acidity and reducibility of red mud, which were critical for SCR reac...
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Article
Open AccessEffect of organic acids on growth performance, intestinal morphology, and immunity of broiler chickens with and without coccidial challenge
A total of 360-day-old broiler chicks were allocated into six groups in 2 (Coccidial challenge or not) × 3 (dietary treatments) factorial design. Three dietary treatments including: basic diet, basic diet plus...
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Article
Arctic sea ice thickness variations from CryoSat-2 satellite altimetry data
Arctic sea ice plays an important role in Earth’s climate and environmental system. Sea ice thickness is one of the most important sea ice parameters. Accurately obtaining the sea ice thickness and its changes...
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Article
Effects of Dietary Iron Concentration on Manganese Utilization in Broilers Fed with Manganese-Lysine Chelate-Supplemented Diet
Dietary iron (Fe) influences manganese (Mn) utilization in chickens fed with inorganic Mn-supplemented diet. This study aimed to determine if dietary Fe levels affect Mn utilization in broilers fed with organi...
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Article
Open AccessStandardization and harmonization of distributed multi-center proteotype analysis supporting precision medicine studies
Cancer has no borders: Generation and analysis of molecular data across multiple centers worldwide is necessary to gain statistically significant clinical insights for the benefit of patients. Here we conceive...
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Article
Effects of Dietary Iron on Manganese Utilization in Broilers Fed with Corn-Soybean Meal Diet
To investigate the effects of dietary iron (Fe) levels on manganese (Mn) utilization, 900 8-day-old broilers were randomly assigned to 1 of 6 treatments in a 3 (Fe level) × 2 (Mn level) factorial arrangement a...
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Article
High Dietary Iron Differentially Influences the Iron Distribution in the Livers and the Spleens of Laying Hens After Salmonella Typhimurium Infection
Salmonella and the host battle for iron (Fe), due to its importance for fundamental cellular processes. To investigate Fe redistribution of Salmonella-infected hens and the effects of high dietary Fe on it, Salmo...
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Article
Open AccessGenome-wide DNA methylation analysis in jejunum of Sus scrofa with intrauterine growth restriction
Intrauterine growth restriction (IUGR) may elicit a series of postnatal body developmental and metabolic diseases due to their impaired growth and development in the mammalian embryo/fetus during pregnancy. In...
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Article
Effect of High Dietary Manganese on the Immune Responses of Broilers Following Oral Salmonella typhimurium Inoculation
Manganese (Mn) is an essential nutrient for both host and pathogen. Recent studies have demonstrated the nutritional immunity of Mn against Salmonella infection in mammals. To investigate the effect of high dieta...
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Article
Open AccessEffects of oil quality and antioxidant supplementation on sow performance, milk composition and oxidative status in serum and placenta
The aim of this study was to determine the effects of oil quality and antioxidant (AOX) supplementation on sow performance, milk composition and oxidative status.
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Article
Open AccessEffect of dietary canthaxanthin and 25-hydroxycholecalciferol supplementation on the performance of duck breeders under two different vitamin regimens
Dietary canthaxanthin (CX), 25-hydroxycholecalciferol (25-OH-D 3 ) and vitamins have been widely reported to be involved in productive and reprodu...
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Article
Multiplexed peptide analysis using data-independent acquisition and Skyline
Skyline is a targeted proteomics environment that can be used in the detection and quantitation of peptides. In this protocol the MS/MS peptide data is generated by data-independent acquisition on a Q-Exactive...
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Article
Open AccessEffects of a multi-enzyme complex on growth performance, nutrient utilization and bone mineralization of meat duck
Previous studies with broiler have shown dietary supplementation with multi-enzyme complex containing non-starch polysaccharides (NSP) degrading enzymes and phytase is efficient in releasing phosphorus (P), ca...
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The Role of Home-Literacy Environment in Learning to Read Chinese
The purpose of this study is to examine the relation between home-literacy environment and Chinese children’s reading development. Information about four parameters of home-literacy environment (literacy resou...
