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  1. Article

    Open Access

    An immune gene signature to predict prognosis and immunotherapeutic response in lung adenocarcinoma

    Lung adenocarcinoma is one of the most common malignant tumors worldwide. The purpose of this study was to construct a stable immune gene signature for prediction of prognosis (IGSPP) and response to immune ch...

    Hongquan Chen, Renxi Lin, Weibin Lin, Qing Chen, Dongjie Ye, **g Li… in Scientific Reports (2022)

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  2. Article

    Open Access

    The deubiquitinating enzyme OTUD1 antagonizes BH3-mimetic inhibitor induced cell death through regulating the stability of the MCL1 protein

    Myeloid cell leukaemia 1 (MCL1) is a pro-survival Bcl-2 family protein that plays important roles in cell survival, proliferation, differentiation and tumourigenesis. MCL1 is a fast-turnover protein that is de...

    Lanqin Wu, Yingying Lin, **an Feng, Yuanlin Qi, **nrui Wang… in Cancer Cell International (2019)

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  3. No Access

    Article

    Deficient PKR in RAX/PKR Association Ameliorates Ethanol-Induced Neurotoxicity in the Develo** Cerebellum

    Ethanol-induced neuronal loss is closely related to the pathogenesis of fetal alcohol spectrum disorders. The cerebellum is one of the brain areas that are most sensitive to ethanol. The mechanism underlying e...

    Hui Li, Jian Chen, Yuanlin Qi, Lu Dai, Mingfang Zhang… in The Cerebellum (2015)