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Article
Spatial Organization of the Components of the Serotonergic System in the Early Mouse Development
Serotonin is a regulator of early embryonic development and has a complete functional system in preimplantation mammalian embryos. In the present work, the spatial distribution of serotonin, the vesicular mono...
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Article
The Serotonin System in Mammalian Oogenesis
Transmitters, particularly serotonin, not only have the classical function of transmitting nerve impulses, but also take part in a whole series of regulatory processes throughout ontogeny, including those occu...
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Article
On the Intracellular Transmitter Reception
The idea on the possibility of intracellular neurotransmitter receptor localization exists already more than half a century, however it remains disputable until now. The data on such neurotransmitter receptors...
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Article
Expression of Components of the Serotonergic System in Folliculogenesis and Preimplantation Development in Mice
The functions of serotonin include the growth and development regulation of female germ cells as well as early embryo development. RT-PCR analysis of mRNA expression of the genes of the enzymes for synthesis a...
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Article
Expression of transmitter receptor genes in early development of sea urchin Paracentrotus lividus
Neurotransmitters (including serotonin and acetylcholine) perform a number of prenervous functions in early sea urchin development. To detect the particular receptor components involved in these processes, we ...
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Article
A “micromere model” of cell-cell interactions in sea urchin early embryos
It has been shown that isolation of sea urchin blastomeres before the post-division adhesion leads mainly to the formation of equal blastomeres at the stage of 4th cleavage division, whereas isolation after ad...
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Article
Effect of local microapplication of serotonergic drugs on membrane currents of Paracentrotus lividus early embryos
It was shown that local application of agonists of the 3rd type receptors 5-HTQ and quipazine into the interblastomere cleft of Paracentrotus lividus embryos evoked specific membrane currents. At the same time, l...
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Article
Changes in the physiological roles of neurotransmitters during individual development
The classical neurotransmitters (acetylcholine and biogenic monoamines) are multifunctional substances involved in intra- and intercellular signaling at all stages of ontogenesis in multicellular animals. A cy...
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Article
Effect of cyclic nucleotides on sensitivity of early sea urchin embryos to cytotoxic neuropharmacological drugs
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Article
Possible role of “prenervous” neurotransmitters in cellular interactions of early embryogenesis: A hypothesis
Evidence is presented in support of the working hypothesis that “prenervous” neurotransmitters directly participate in cell-cell interactions occurring during the first several cleavage divisions of sea urchin...
