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  1. No Access

    Article

    Prostate tumor-induced stromal reprogramming generates Tenascin C that promotes prostate cancer metastasis through YAP/TAZ inhibition

    Metastatic prostate cancer (PCa) in bone induces bone-forming lesions that enhance PCa progression. How tumor-induced bone formation enhances PCa progression is not known. We have previously shown that PCa-ind...

    Yu-Chen Lee, Song-Chang Lin, Guoyu Yu, Ming Zhu, Jian H. Song, Keith Rivera in Oncogene (2022)

  2. No Access

    Article

    Statins reduce castration-induced bone marrow adiposity and prostate cancer progression in bone

    A fraction of patients undergoing androgen deprivation therapy (ADT) for advanced prostate cancer (PCa) will develop recurrent castrate-resistant PCa (CRPC) in bone. Strategies to prevent CRPC relapse in bone ...

    Tianhong Pan, Song-Chang Lin, Yu-Chen Lee, Guoyu Yu, Jian H. Song, **g Pan in Oncogene (2021)

  3. Article

    Open Access

    Short-term effect of electroacupuncture on rehabilitation after arthroscopic triangular fibrocartilage complex repair: a randomised study

    Electroacupuncture (EA) alleviates chronic pain and acute postoperative pain after several surgical procedures. However, whether EA facilitates postoperative functional recovery after arthroscopic surgery has ...

    Chiu-Ming Chang, Cheng-En Hsu, Yu-Chen Lee in Journal of Orthopaedic Surgery and Research (2021)

  4. Article

    Open Access

    Acorus tatarinowii Schott extract reduces cerebral edema caused by ischemia–reperfusion injury in rats: involvement in regulation of astrocytic NKCC1/AQP4 and JNK/iNOS-mediated signaling

    This study aimed to evaluate the effects of the Acorus tatarinowii Schott [Shi Chang Pu (SCP)] extract administered at the start of 2 h of middle cerebral artery occlusion (MCAo), followed by 3 d of reperfusion, ...

    Yu-Chen Lee, Shung-Te Kao, Chin-Yi Cheng in BMC Complementary Medicine and Therapies (2020)

  5. Article

    Open Access

    Bone secreted factors induce cellular quiescence in prostate cancer cells

    Disseminated tumor cells (DTCs) undergo a dormant state in the distant metastatic site(s) before becoming overt metastatic diseases. In prostate cancer (PCa), bone metastasis can occur years after prostatectom...

    Li-Yuan Yu-Lee, Yu-Chen Lee, **g Pan, Song-Chang Lin, Tianhong Pan in Scientific Reports (2019)

  6. Article

    Open Access

    Trends in the utilization of acupuncture among children in Taiwan from 2002 to 2011: a nationwide population-based study

    In recent years, acupuncture has been increasingly integrated into pediatric care worldwide. However, recent epidemiological studies about pediatric users of acupuncture are lacking. The current study aimed to...

    Chieh Wang, Yu-Chen Lee, Mei-Yao Wu in BMC Complementary and Alternative Medicine (2019)

  7. Article

    Open Access

    Acupuncture decreased the risk of coronary heart disease in patients with rheumatoid arthritis in Taiwan: a Nationwide propensity score-matched study

    Patients with rheumatoid arthritis (RA) have a higher risk of coronary heart disease (CHD). Acupuncture, a commonly used treatment for patients with RA, has not been reported to prevent CHD in patients with RA...

    Mei-Yao Wu, Ming-Cheng Huang, Hou-Hsun Liao in BMC Complementary and Alternative Medicine (2018)

  8. No Access

    Article

    Effects of self-assembled sorbitol-derived compounds on the structures and properties of biodegradable poly(L-lactic acid) prepared by melt blending

    The microstructures and characteristics of biodegradable poly(L-lactic acid) (PLLA) with 1,3:2,4-dibenzylidene-D-sorbitol (DBS) prepared by melt blending were investigated in this study. DBS was added as a dil...

    Wei-Chi Lai, Yu-Chen Lee in Journal of Polymer Research (2018)

  9. No Access

    Article

    Systematic design an intelligent simulation training system: from learn-memorize perspective

    Intelligent manufacturing provides a wide range of benefits such as optimizing production system via the behavioral instructions of cyber-physical system (CPS). Yet successful intelligent manufacturing is conf...

    Jung-Nan Yen, Hsiang-Chin Hung, Hsiang-Chen Hsu, Yu-Chen Lee in Microsystem Technologies (2018)

  10. No Access

    Chapter

    Experimental Study of Electroacupuncture Therapy in Diabetes Mellitus

    Aim and Background: Acupuncture and moxibustion was applied in the treatment of diabetes mellitus (DM), which was termed the **ao-Ke syndrome in traditional Chinese medicine (TCM). Also, the metabolic syndrome (M...

    Shih-Liang Chang, Yu-Chen Lee, Jaung-Geng Lin in Experimental Acupuncturology (2018)

  11. Article

    Open Access

    Complementary traditional Chinese medicine use in Children with cerebral palsy: a nationwide retrospective cohort study in Taiwan

    Complementary traditional Chinese medicine (TCM) has been used to treat patients with cerebral palsy (CP). However, large-scale surveys examining its use in the treatment of CP and associated disorders are lac...

    Hou-Hsun Liao, Hung-Rong Yen, Chih-Hsin Muo in BMC Complementary and Alternative Medicine (2017)

  12. Article

    Open Access

    Acupuncture decreased the risk of coronary heart disease in patients with fibromyalgia in Taiwan: a nationwide matched cohort study

    The aim of this study was to understand whether acupuncture can decrease the risk of coronary heart disease (CHD) in patients with fibromyalgia.

    Mei-Yao Wu, Ming-Cheng Huang, Jen-Huai Chiang, Mao-Feng Sun in Arthritis Research & Therapy (2017)

  13. Article

    Open Access

    The High-efficiency LED Driver for Visible Light Communication Applications

    This paper presents a LED driver for VLC. The main purpose is to solve the low data rate problem used to be in switching type LED driver. The GaN power device is proposed to replace the traditional silicon pow...

    Cihun-Siyong Alex Gong, Yu-Chen Lee, Jyun-Liang Lai, Chueh-Hao Yu in Scientific Reports (2016)

  14. Article

    Open Access

    Antipruritic effect of cold stimulation at the Quchi Acupoint (LI11) in Mice

    Acupuncture and moxibustion are used to treat pruritus and atopic dermatitis. However, whether cold stimulation (defined as that the temperature conducted under skin temperature) of acupoints affects itching i...

    Kao-Sung Tsai, Yung-Hsiang Chen, Huey-Yi Chen in BMC Complementary and Alternative Medicine (2014)

  15. Article

    Open Access

    Peroxisome proliferator-activated receptor activating hypoglycemic effect of Gardenia jasminoides Ellis aqueous extract and improvement of insulin sensitivity in steroid induced insulin resistant rats

    The active components of Gardenia (Gardenia jasminoides Ellis, GJ) exhibit a hypoglycemic effect by improving insulin secretion and lowering plasma lipids. In the present study, we fed a water extract of gardenia...

    Ying-I Chen, Yu-Wen Cheng, Chung-Yuh Tzeng in BMC Complementary and Alternative Medicine (2014)

  16. No Access

    Protocol

    Plasma Membrane Isolation Using Immobilized Concanavalin A Magnetic Beads

    Isolation of highly purified plasma membranes is the key step in constructing the plasma membrane proteome. Traditional plasma membrane isolation method takes advantage of the differential density of organelle...

    Yu-Chen Lee, Martina Srajer Gajdosik, Djuro Josic, Sue-Hwa Lin in Liver Proteomics (2012)

  17. Article

    Open Access

    Acute effect of electroacupuncture at the Zusanli acupoints on decreasing insulin resistance as shown by lowering plasma free fatty acid levels in steroid-background male rats

    Insulin sensitivity has been enhanced by electroacupuncture (EA) in rats, but the EA phenomenon in an insulin resistant state is still unclear. This study reports the use of a large dose of prednisolone to eva...

    Rong-Tsung Lin, Chung-Yuh Tzeng, Yu-Chen Lee in BMC Complementary and Alternative Medicine (2009)

  18. No Access

    Article

    Using Chitosan as a Coagulant in Recovery of Organic Matters from the Mash and Lauter Wastewater of Brewery

    Chitosan is a natural biopolymer which can be used to replace aluminum salts and chemical polymers as a coagulant to avoid the human health problems caused by the residual of aluminum and chemical polymers in ...

    Wen Po Cheng, Fung Hwa Chi, Ruey Fang Yu in Journal of Polymers and the Environment (2005)