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Article
A Comprehensive Study on the Consequences of Gap-Graded Sands Considering the Loss of Fine Particles
Water and sand leakage disasters are likely to occur during construction in water-rich sand layer areas, resulting in ground collapse. The stress-strain action characteristics of discontinuous graded sand unde...
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Article
Open AccessJuglone induces ferroptosis in glioblastoma cells by inhibiting the Nrf2-GPX4 axis through the phosphorylation of p38MAPK
Ferroptosis, a non-apoptotic form of cell death induced by accumulation of free iron ions and lipid peroxidation, its importance for cancer treatment is gradually being recognized. Research on the anti-cancer ...
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Article
Toward designing highly effective and efficient consensus mechanisms for blockchain-based applications
Consensus mechanism (CM) is the heart and soul of blockchain, for it allows nodes in a blockchain network to reach an agreement on the state of system execution. Among the CMs, the right for constructing the n...
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Article
Open AccessAPOB is a potential prognostic biomarker in hepatocellular carcinoma
Hepatocellular carcinoma (HCC) is significantly associated with adverse prognostic outcomes. The development and progression of different types of human tumors are significantly influenced by APOB. Nevertheles...
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Article
Survivin degradation by bergenin overcomes pemetrexed resistance
Chemoresistance is a primary factor for treatment failure and tumor recurrence in non-small cell lung cancer (NSCLC) patients. The oncoprotein survivin is commonly upregulated in human malignancies and is asso...
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Article
High GLUT1 membrane expression and low PSMA membrane expression in Ductal Adenocarcinoma and Intraductal Carcinoma of the prostate
Both Ductal Adenocarcinoma (DAC) and Intraductal Carcinoma (IDC) of the prostate are generally associated with aggressive clinical behavior and poor prognosis, which were linked with discordant FDG positivity ...
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Article
Open AccessAutomated player identification and indexing using two-stage deep learning network
American football games attract significant worldwide attention every year. Identifying players from videos in each play is also essential for the indexing of player participation. Processing football game vid...
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Article
Asymptotic Estimations of Eigenvalues and Eigenfunctions for Nonlocal Boundary Value Problems with Eigenparameter-Dependent Boundary Conditions
The nonlocal boundary value problem with eigenparameter dependent boundary conditions is studied in this work. Firstly, we give the asymptotic expressions of the general solution for the equation corresponding...
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Article
A prospective comparative study of [68Ga]Ga-RM26 and [68Ga]Ga-PSMA-617 PET/CT imaging in suspicious prostate cancer
Prostate-specific membrane antigen (PSMA)–based PET/CT imaging has limitations in the diagnosis of prostate cancer (PCa). We recruited 207 participants with suspicious PCa to perform PET/CT imaging with radiol...
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Article
Exosomes loaded with circPARD3 promotes EBV-miR-BART4-induced stemness and cisplatin resistance in nasopharyngeal carcinoma side population cells through the miR-579-3p/SIRT1/SSRP1 axis
To explore the effects of exosomes loaded with circular RNA PARD3 on EBV-miR-BART4-induced stemness and resistance of cisplatin in nasopharyngeal carcinoma side population (NPC-SP) cells through the miR-579-3p...
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Article
Open AccessDifferent channels to transmit information in scattering media
A communication channel should be built to transmit information from one place to another. Imaging is 2 or higher dimensional information communication. Conventionally, an imaging channel comprises a lens with...
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Article
Open AccessTRAF4-mediated ubiquitination-dependent activation of JNK/Bcl-xL drives radioresistance
The E3 ligase TNF receptor-associated factor 4 (TRAF4) is upregulated and closely associated with tumorigenesis and the progression of multiple human malignancies. However, its effect on radiosensitivity in co...
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Article
Open AccessAuthor Correction: Butein promotes ubiquitination-mediated survivin degradation inhibits tumor growth and overcomes chemoresistance
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Article
Open AccessCorrection to: Stabilization of MCL-1 by E3 ligase TRAF4 confers radioresistance
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Chapter and Conference Paper
Feasibility Analysis of Pipeline In-Situ Break-and-Replace Method
At present, the more popular trenchless pipeline repair technology mainly adopts the method of strengthening the inner wall. However, in the case of serious pipeline damage or need to increase the water capaci...
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Chapter and Conference Paper
Analysis of Construction Technology and Soil Settlement Law for In-Situ Break-and-Replace of Pipelines
In order to solve the problem of renewing the whole structure of the old pipeline, this paper proposes a new construction method for mechanized non-excavation pipelines in-situ break-and-replace method (PBR). ...
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Article
Open AccessStabilization of MCL-1 by E3 ligase TRAF4 confers radioresistance
The E3 ligase TNF receptor-associated factor 4 (TRAF4) is frequently overexpressed and closely related to poor prognosis in human malignancies. However, its effect on carcinogenesis and radiosensitivity in ora...
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Article
Open AccessButein promotes ubiquitination-mediated survivin degradation inhibits tumor growth and overcomes chemoresistance
Overexpression of survivin is frequently observed in human malignancies and is associated with poor prognosis. The present study found that survivin is highly expressed in nasopharyngeal carcinoma (NPC) tumor ...
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Article
The efficacy of transarterial chemoembolization in downstaging unresectable hepatocellular carcinoma to curative therapy: a predicted regression model
Patients with hepatocellular carcinoma (HCC) outside Milan criteria (MC) may be candidates for curative therapy after successful downstaging. We aimed to identify the predictors of successful downstaging of un...
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Article
Characteristics of EPS from Pseudomonas aeruginosa and Alcaligenes faecalis under Cd(II) stress: changes in chemical components and adsorption performance
EPS (extracellular polymeric substance) production is a self-protection mechanism by which microorganisms slow or eliminate adverse effects in unfavorable environments. In this study, Pseudomonas aeruginosa and A...
