-
Article
Open AccessThe 50% and 95% effective dose of remimazolam tosilate for anaesthesia induction in sleep disorders patients undergoing laparoscopic cholecystectomy: an up-and-down sequential allocation trial
Previous reports argue that preoperative sleep conditions of patients can influence the dosage of general anaesthesia drugs. Therefore, we aimed to investigate the dose-effect relationship of preoperative slee...
-
Article
miR-511-5p Suppresses Cell Migration, Invasion and Epithelial–Mesenchymal Transition Through Targeting PAK2 in Gastric Cancer
As a malignant tumor, gastric cancer (GC) is closely related with gastric mucosa and has a high mortality in the world. Since microRNA (miRNA) has become more and more important in tumor research, we intend to...
-
Article
Substance P modulates BMSCs migration for tissue repair through NK-1R/CXCR4/p-Akt signal activation
The migration of bone marrow-derived mesenchymal stem cells (BMSCs) to the wound site played an important role in tissue repair. Substance P (SP) has been studied and reported to be involved in tissue repair b...
-
Chapter and Conference Paper
Hierarchical Memory Learning for Fine-Grained Scene Graph Generation
Regarding Scene Graph Generation (SGG), coarse and fine predicates mix in the dataset due to the crowd-sourced labeling, and the long-tail problem is also pronounced. Given this tricky situation, many existing...
-
Article
Clinical characteristics and predictors of permanent stoma in rectal cancer patients underwent anterior resections: the value of preoperative prognostic nutritional index
This study was aimed to investigate the correlation between preoperative prognostic nutritional index (PNI) and permanent stoma (PS) in patients with defunctioning stoma (DS) after anterior resections and, bas...
-
Article
Open AccessPhf8 histone demethylase deficiency causes cognitive impairments through the mTOR pathway
Epigenomic abnormalities caused by genetic mutation in epigenetic regulators can result in neurodevelopmental disorders, deficiency in neural plasticity and mental retardation. As a histone demethylase, plant ...
-
Article
Open AccessSystemic blockade of P2X7 receptor protects against sepsis-induced intestinal barrier disruption
Sepsis, during which the intestinal epithelial barrier is frequently disrupted, remains a challenging and life-threatening problem in clinical practice. The P2X7 receptor (P2X7R) is a non-selective adenosine t...
-
Article
Open AccessInjectable in situ cross-linking chitosan-hyaluronic acid based hydrogels for abdominal tissue regeneration
Abdominal wall defect caused by open abdomen (OA) or abdominal trauma is a serious issue since it induces several clinical problems. Although a variety of prosthetic materials are commonly employed, complicati...
