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  1. Article

    Open Access

    Deep phenoty** of post-infectious myalgic encephalomyelitis/chronic fatigue syndrome

    Post-infectious myalgic encephalomyelitis/chronic fatigue syndrome (PI-ME/CFS) is a disabling disorder, yet the clinical phenotype is poorly defined, the pathophysiology is unknown, and no disease-modifying tr...

    Brian Walitt, Komudi Singh, Samuel R. LaMunion, Mark Hallett in Nature Communications (2024)

  2. Article

    Open Access

    Immunovirological markers in HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP)

    Human T cell lymphotropic virus 1 (HTLV-1) is a human retrovirus and infects approximately 10–20 million people worldwide. While the majority of infected people are asymptomatic carriers of HTLV-1, only 4% of ...

    Yoshimi Enose-Akahata, Steven Jacobson in Retrovirology (2019)

  3. Article

    Open Access

    Viral antigens detectable in CSF exosomes from patients with retrovirus associated neurologic disease: functional role of exosomes

    HTLV-1 infects over 20 million people worldwide and causes a progressive neuroinflammatory disorder in a subset of infected individuals called HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP...

    Monique R. Anderson, Michelle L. Pleet in Clinical and Translational Medicine (2018)

  4. Article

    Open Access

    Development of neurologic diseases in a patient with primate T lymphotropic virus type 1 (PTLV-1)

    Virus transmission from various wild and domestic animals contributes to an increased risk of emerging infectious diseases in human populations. HTLV-1 is a human retrovirus associated with acute T-cell leukem...

    Yoshimi Enose-Akahata, Breanna Caruso, Benjamin Haner, Emily Charlip in Retrovirology (2016)

  5. Article

    Immunophenoty** of cerebrospinal fluid cells in virus-associated neurologic diseases

    Yoshimi Enose-Akahata, Raya Massoud, Breanna Caruso, Joan Ohayon in Retrovirology (2015)

  6. Article

    Development of HTLV-1 associated myelopathy/tropical spastic paraparesis in a patient with simian T-lymphotropic virus type 1-like infection.

    Yoshimi Enose-Akahata, Breanna Caruso, Benjamin Haner, Raya Massoud in Retrovirology (2015)

  7. No Access

    Article

    Epigenetic Modification of the FoxP3 TSDR in HAM/TSP Decreases the Functional Suppression of Tregs

    HTLV-1 is a human retrovirus that is associated with the neuroinflammatory disorder HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP). In these patients, HTLV-1 is primarily found in the CD4+CD2...

    Monique R. Anderson, Yoshimi Enose-Akahata in Journal of Neuroimmune Pharmacology (2014)

  8. Article

    Open Access

    Clinical trial of a humanized monoclonal anti-IL15Rβ (CD122), in HTLV-1 associated myelopathy/ tropical spastic paraparesis (HAM/TSP)

    Raya Massoud, Yoshimi Enose-Akahata, Giovanna S Brunetto, Joan Ohayon in Retrovirology (2014)

  9. Article

    Open Access

    Correlation of increased CXCL13 with intrathecal humoral immune responses to HTLV-1 in CSF of patients with HAM/TSP

    Yoshimi Enose-Akahata, Raya Massoud, Jussi O Virtanen, Steven Jacobson in Retrovirology (2014)

  10. Article

    Open Access

    Humoral immune response to HTLV-1 basic leucine zipper factor (HBZ) in HTLV-1-infected individuals

    Yoshimi Enose-Akahata, Anna Abrams, Raya Massoud, Izabela Bialuk in Retrovirology (2014)

  11. Article

    Open Access

    BNZ-gamma peptide, a potential therapeutic agent in HTLV-1 associated myelopathy

    Raya Massoud, Yoshimi Enose-Akahata, Yutaka Tagaya, Nazli Azimi in Retrovirology (2014)

  12. Article

    Open Access

    Humoral immune response to HTLV-1 basic leucine zipper factor (HBZ) in HTLV-1-infected individuals

    Human T cell lymphotropic virus type 1 (HTLV-1) infection can lead to development of adult T cell leukemia/lymphoma (ATL) or HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) in a subset of i...

    Yoshimi Enose-Akahata, Anna Abrams, Raya Massoud, Izabela Bialuk in Retrovirology (2013)

  13. Article

    Open Access

    Minocycline modulates antigen-specific CTL activity through inactivation of mononuclear phagocytes in patients with HTLV-I associated neurologic disease

    The activation of mononuclear phagocytes (MPs), including monocytes, macrophages and dendritic cells, contributes to central nervous system inflammation in various neurological diseases. In HTLV-I-associated m...

    Yoshimi Enose-Akahata, Eiji Matsuura, Yuetsu Tanaka, Unsong Oh in Retrovirology (2012)