28 Result(s)

Article

2022 World Hypertension League, Resolve To Save Lives and International Society of Hypertension dietary sodium (salt) global call to action

Norm R. C. Campbell, Paul K. Whelton, Marcelo Orias… in Journal of Human Hypertension (2023)

Article

Study design and baseline characteristics of a population-based prospective cohort study of dementia in Japan: the Japan Prospective Studies Collaboration for Aging and Dementia (JPSC-AD)

The burden of dementia is growing rapidly and has become a medical and social problem in Japan. Prospective cohort studies have been considered an effective methodology to clarify the risk factors and the etio...

Toshiharu Ninomiya, Shigeyuki Nakaji… in Environmental Health and Preventive Medici… (2020)

Article

Gene and environmental interactions according to the components of lifestyle modifications in hypertension guidelines

Risk factors for hypertension consist of lifestyle and genetic factors. Family history and twin studies have yielded heritability estimates of BP in the range of 34–67%. The most recent paper of BP GWAS has ex...

Yoshihiro Kokubo, Sandosh Padmanabhan… in Environmental Health and Preventive Medici… (2019)

Article

For making a declaration of countermeasures against the falling birth rate from the Japanese Society for Hygiene: summary of discussion in the working group on academic research strategy against an aging society with low birth rate

In 1952, the Japanese Society for Hygiene had once passed a resolution at its 22nd symposium on population control, recommending the suppression of population growth based on the idea of cultivating a healthie...

Kyoko Nomura, Kanae Karita, Atsuko Araki… in Environmental Health and Preventive Medici… (2019)

Article

A comprehensive policy for reducing sugar beverages for healthy life extension

The excessive consumption of sugar-sweetened beverages is a public health concern worldwide. Several clinical trials examining the effects of consuming sucrose or high-fructose corn syrup demonstrated the link...

Yoshihiro Kokubo, Aya Higashiyama… in Environmental Health and Preventive Medici… (2019)

Article

Impact of hypertension on the lifetime risk of coronary heart disease

The lifetime risk estimate conveys the probability of disease in the remaining lifetime for an index age. These estimates may be useful for general audience-targeted knowledge translation activities against hy...

Tanvir Chowdhury Turin, Tomonori Okamura, Arfan Raheen Afzal… in Hypertension Research (2016)

Article

Erratum: Alcohol consumption and cardiovascular disease incidence in men with and without hypertension: the Suita study

Correction to: Hypertension Research (2013) 36, 58–64; doi:10.1038/hr.2012.133; published online 30 August 2012 After the publication of this article, the authors noticed an error in the Abstract. The number o...

Aya Higashiyama, Tomonori Okamura, Makoto Watanabe… in Hypertension Research (2013)

Article

Alcohol consumption and cardiovascular disease incidence in men with and without hypertension: the Suita study

The relationship between alcohol consumption and the risk for cardiovascular disease (CVD) is U-shaped, whereas alcohol drinking is linearly associated with blood pressure, and the CVD risk also increases line...

Aya Higashiyama, Tomonori Okamura, Makoto Watanabe… in Hypertension Research (2013)

Article

Association of intima-media thickening of carotid artery with genetic polymorphisms of the regulator of G-protein signaling 2 gene in patients with hypertension and in the general population

Regulator of G-protein signaling 2 (RGS2) is a key molecule in signal pathways of vasoactive peptides, such as angiotensin II and endothelin 1, and is believed to have an important role in the pathophysiology ...

Kei Kamide, Yoshihiro Kokubo, ** Yang, Shin Takiuchi… in Hypertension Research (2011)

Article

The combined impact of blood pressure category and glucose abnormality on the incidence of cardiovascular diseases in a Japanese urban cohort: the Suita Study

Few prospective studies have examined the combined impact of blood pressure (BP) categories and glucose abnormalities on the incidence of cardiovascular disease (CVD) in the general Asian population. This stud...

Yoshihiro Kokubo, Tomonori Okamura, Makoto Watanabe… in Hypertension Research (2010)

Article

Impact of Metabolic Syndrome Components on the Incidence of Cardiovascular Disease in a General Urban Japanese Population: The Suita Study

Abdominal obesity is a prerequisite for some definitions of metabolic syndrome (MetS). We investigated the impact of MetS defined by two different criteria, which either did or did not require abdominal obesit...

Yoshihiro Kokubo, Tomonori Okamura, Yasunao Yoshimasa… in Hypertension Research (2008)

Article

Effects of the Y Chromosome on Cardiovascular Risk Factors in Japanese Men

Excess cardiovascular risk in men compared with women has been suggested to be partly explained by effects of the Y chromosome. However, inconsistent results have been reported on the Y chromosome's genetic in...

Yumiko Hiura, Yasue Fukushima, Yoshihiro Kokubo, Tomonori Okamura… in Hypertension Research (2008)

Article

Genetic Variations of CYP2C9 in 724 Japanese Individuals and Their Impact on the Antihypertensive Effects of Losartan

CYP2C9, a drug-metabolizing enzyme, converts the angiotensin II receptor blocker losartan to its active form, which is responsible for its antihypertensive effect. We resequenced CYP2C9 in 724 Japanese individ...

Tong Yin, Keiko Maekawa, Kei Kamide, Yoshiro Saito… in Hypertension Research (2008)

Article

Leptin Gene and Leptin Receptor Gene Polymorphisms Are Associated with Sweet Preference and Obesity

Leptin is an adipocyte-secreted hormone that regulates food intake and body weight, and that was recently reported to suppress sweet sensitivity in an animal model. We investigated the associations among sweet...

Einosuke Mizuta, Yoshihiro Kokubo, Itaru Yamanaka… in Hypertension Research (2008)

Article

Associations of Hypertension and Its Complications with Variations in the Xanthine Dehydrogenase Gene

Hyperuricemia and oxidative stress participate in the pathophysiology of hypertension and its complications. Xanthine dehydrogenase (XDH) produces urate and, in its oxidase isoform, reactive oxygen species. He...

** Yang, Kei Kamide, Yoshihiro Kokubo, Shin Takiuchi… in Hypertension Research (2008)